Director of Research at Calico | South San Francisco

Join AbbVie as an Associate Director in our R&D Information Research IT team, where you will play a pivotal role in driving innovation and supporting our research initiatives. In this hybrid position, you will collaborate with cross-functional teams to enhance our information systems and contribute to the advancement of groundbreaking therapies.

Join Our Vision at insitroinsitro is on the hunt for a dynamic Senior Director of External Research & Development to spearhead all facets of our external R&D portfolio. This pivotal leadership role is accountable for crafting and executing the company’s external R&D strategy, defining and optimizing our collaborations with preclinical and research contract research organizations (CROs).In this strategic capacity, you will work closely with senior leaders across diverse functions, including Research, Drug Discovery, Technical Operations, Corporate Development & Strategy, Finance, and Project Management, ensuring a seamless approach to alliance and outsourcing management.Reporting directly to the Chief Technical Operations Officer, this position welcomes both remote and local candidates, offering flexibility to work onsite (3 days per week) at our South San Francisco office or a hybrid model (~1 week per month) with some travel (up to 25%) to oversee partnerships both domestically and internationally.Key ResponsibilitiesExternal R&D Strategy: Drive a comprehensive external research strategy, aligning with corporate objectives and supporting the research portfolio. Represent insitro in senior-level partnership discussions and negotiations, ensuring effective management of business partnerships.Partner Network Management: Cultivate and oversee innovative relationships with a strategic network of high-quality CROs and external partners, maintaining the highest scientific and ethical standards.Project Execution & Oversight: Ensure the successful planning, monitoring, and execution of externally sourced projects across the vendor network, adhering to project goals, budgets, and timelines. Foster strong communication and partnership with internal stakeholders.Governance & Compliance: Develop effective governance models and collaborate with Legal and Procurement on partner selection, negotiations, and agreement execution.Process & Team Leadership: Lead a team to implement industry-leading processes in vendor management, ensuring compliance with contractual obligations and standard operating procedures (SOPs).Operational Review & Improvement: Regularly assess the overall scope of outsourced services to ensure resource efficiency and effectiveness.

Join Spirair Inc., a pioneering company dedicated to advancing medical technologies, as a Senior R&D Engineer. In this role, you will leverage your expertise to drive the development of innovative medical devices, collaborating with a multidisciplinary team to ensure compliance with regulatory standards and enhance patient outcomes.

At Alumis Inc., we are dedicated to revolutionizing the lives of patients suffering from autoimmune diseases through precision medicine. Despite recent treatment advancements, many individuals continue to endure challenges related to immunologic conditions. Our mission is to fundamentally improve patient outcomes.We are in search of a proactive and skilled leader to join our IT team as a Senior Manager, IT, R&D Applications (Contractor). In this pivotal role, you will support essential business applications that cater to the corporate needs of our Development and Research teams, including Quality Assurance, Clinical Operations, Biometrics, Medical Affairs, and Regulatory functions. Additionally, you will play a crucial role in enterprise-level initiatives. Working closely with various stakeholders, you will manage the implementation, maintenance, and ongoing support of SaaS technologies that enhance operational efficiency and drive business success. The ideal candidate should possess a robust technical background, demonstrate excellent organizational skills, work independently, and embody a positive, solution-oriented mindset. This position reports directly to the Director of R&D Business Partner.

Role overview Calico Labs is hiring a Director or Associate Director of Toxicology to lead research into the safety profiles of compounds under development. This leadership role shapes the approach to evaluating toxicological effects and plays a key part in decisions that guide the direction of health research at Calico Labs. Key responsibilities Direct research initiatives to assess the toxicological impacts of compounds in the development pipeline Guide safety and efficacy evaluations at each stage of the development process Work closely with scientific teams to inform study design and interpret results Apply toxicology expertise to advance Calico Labs' mission in health innovation Location This position is based in South San Francisco, CA.

Join Veracyte, a pioneering leader in genomic diagnostics, as a Clinical Research Associate. In this dynamic role, you will be integral to the design, execution, and management of clinical trials. Your expertise will help drive the development of innovative tests that enhance patient care.

Calico Labs seeks an Associate Director or Director of In Vivo Physiology to join its team in South San Francisco, CA. This leadership role centers on research aimed at understanding and addressing diseases linked to aging. Role overview The Associate Director or Director will shape the scientific direction for in vivo physiology studies. This position supports Calico’s mission to advance health through research focused on age-related conditions. Key responsibilities Guide research projects that investigate the biology of aging and related diseases Direct scientific strategy and help set priorities for the in vivo physiology group Support Calico’s broader goals by fostering collaboration and scientific excellence Location This position is based in South San Francisco, CA.

Join AbbVie as an Associate Director of Innovation, where you will play a crucial role in driving the future of our research and development initiatives. This dynamic position allows you to collaborate with cross-functional teams to identify and implement innovative solutions that enhance our product offerings.

About Us Kardigan is a pioneering heart health company dedicated to transforming cardiovascular disease into a preventable, treatable condition, aiming to eliminate it as the leading cause of death globally.Our mission is to develop a diverse range of targeted treatments concurrently that will lead to the cures our patients with cardiovascular diseases deserve. Founded by industry leaders Tassos Giannakakos, Jay Edelberg, M.D., Ph.D., and Bob McDowell, Ph.D., Kardigan’s founders have reunited following their success at MyoKardia, where they facilitated the discovery and development of mavacamten, the first cardiac myosin inhibitor, culminating in the acquisition by Bristol Myers Squibb in 2020. We boast a cutting-edge discovery and translational research platform, a pipeline full of late-stage candidates, and an exceptional team devoted to enhancing patient lives. At Kardigan, our values drive our work, interactions, and achievements. We are patient-centered, fiercely committed to improving lives and prioritizing patient needs. We believe in authenticity, fostering an environment of acceptance through honest leadership. With a curiosity-driven mindset, we encourage innovative thinking and adaptability. We strive for team success, supporting one another in our collective mission with urgency and excellence. Finally, we aim to enable the impossible, taking calculated risks to inspire innovation and advance scientific breakthroughs. Our core values empower us daily to make a significant impact. Position Title: Associate Director (AD), BiostatisticsDepartment: Development - Data ScienceReports To: Director, BiostatisticsLocation: South San Francisco, CA or Princeton, NJ

Location: South San Francisco, CA, United StatesJob Identification: 2223Job Schedule: Full timeResponsibilitiesAssist in conducting research experiments under the guidance of a Scientist.Perform laboratory experiments to support the development and optimization of products, services, and technologies, from feasibility studies to application testing and stability assessments.Develop methodologies and prepare Standard Operating Procedures (SOPs) as necessary.Acquire chemicals, materials, and reagents for experiments.Handle and prepare chemicals and biochemical reagents for experimental procedures.Ensure proper disposal of chemical and biological waste, maintaining accurate records as required.Calibrate and maintain scientific instruments and laboratory equipment.Keep organized, detailed, and precise records of all experimental processes and data.Conduct data analysis using tools such as Excel, Tableau, flow cytometry, and image analysis.Deliver project status updates and reports.Review relevant literature and apply advanced knowledge to enhance research outcomes.QualificationsBachelor's degree or higher in Biology, Chemistry, or a related scientific field, with 0-10 years of experience in a research setting (preferably at least 3 years).Experience in conducting experiments involving Next Generation Sequencing (NGS), RT-qPCR, fluorescence spectroscopy, biomolecule conjugation, immunoassays, data analysis, and image analysis.Proven ability to effectively plan, execute, analyze, and document research experiments.Skilled in the operation and maintenance of instruments for chemical and spectroscopic analysis, including fluorescence spectroscopy, flow cytometry, and UV-VIS.Highly organized, adaptable, and capable of multitasking in a fast-paced environment with strict timelines.Excellent attention to detail in making experimental observations.Proficient pipetting skills are required.Familiarity with liquid handling systems is preferred, but not mandatory.Strong verbal and written communication skills are essential, as the role requires frequent updates, reports, technical meetings, and presentations.#LI-LP1About UsMyriad Genetics Inc. is a pioneering company in personalized medicine, committed to transforming patient lives globally through innovative molecular diagnostics. We discover and commercialize tests that assess disease risk, diagnose conditions, evaluate disease progression, and inform treatment decisions across six key medical specialties. Our strategic focus is on maintaining leadership in molecular diagnostics while improving patient care and reducing healthcare costs.

At Alumis Inc., we are passionate about revolutionizing the treatment landscape for individuals suffering from autoimmune diseases. Our commitment to precision medicine drives us to innovate treatments that significantly enhance patient outcomes, addressing the unmet needs of those living with immunologic conditions.We are currently in search of an experienced Associate Director of Biostatistics to lend their statistical acumen and operational support to both early-stage and late-stage clinical programs. This pivotal role will see you acting as the lead statistician for various studies, collaborating with multidisciplinary teams to facilitate clinical development and informed decision-making through data analysis. You will play an active role in critical deliverables, oversee CRO activities, and mentor junior team members, fostering a culture of excellence within our statistical team.

Join Xaira Therapeutics as a Senior Research Associate Scientist specializing in Display Technologies. In this pivotal role, you will be at the forefront of groundbreaking research and development initiatives that are shaping the future of therapeutic solutions. Your expertise will directly contribute to the innovation of our display technology, enhancing our product offerings and impacting the lives of patients worldwide.

Calico Labs is hiring an Associate Director of External Communications based in South San Francisco, CA. This leadership role focuses on shaping and executing external communication strategies to strengthen the company’s public profile. Role overview The Associate Director will oversee how Calico Labs communicates its mission, research, and advancements to the public. The position involves working closely with teams across the organization to craft clear, compelling narratives that highlight the company’s work in biotechnology. What you will do Lead the development and execution of external communication strategies Enhance brand visibility through effective storytelling and media outreach Manage media relations to ensure accurate and broad coverage of company initiatives Collaborate with cross-functional teams to align messaging Build partnerships and engage with key stakeholders Requirements Proven experience in public relations and strategic communication Strong background in managing media relations Ability to develop and deliver clear, engaging narratives Experience collaborating with multiple teams This position offers the chance to play a central role in how Calico Labs shares its vision and progress with the world.

Join AbbVie as an Associate Director of AI Transformation, where you will play a pivotal role in driving our AI initiatives to enhance patient outcomes and operational efficiency. This leadership position requires a blend of strategic vision and technical expertise, ensuring our AI solutions align with our organizational goals.In this role, you will lead a cross-functional team, collaborate with stakeholders, and leverage cutting-edge AI technologies. Your contributions will directly impact our commitment to innovation and excellence in healthcare.

Role Overview Oric Pharmaceuticals is seeking an Associate Director of Process Chemistry based in South San Francisco. This position shapes the direction of drug development by designing and refining synthetic routes for new therapeutic candidates. The work emphasizes both operational efficiency and scalability. What You Will Do Lead a team of chemists focused on process chemistry projects Guide the design and optimization of synthetic methods for new drug candidates Develop processes that meet standards for safety, compliance, and scientific rigor Promote collaboration and support a culture of innovation within the team Growth and Development Oric Pharmaceuticals offers opportunities for ongoing learning and professional advancement as part of a growing biotechnology company.

About Us: Calico Life Sciences LLC, a pioneering research and development entity backed by Alphabet, is dedicated to advancing the understanding of human aging through innovative technologies and modeling systems. Our mission is to leverage this knowledge to develop interventions that enhance health span, enabling individuals to live longer, healthier lives. With a commitment to curiosity-driven scientific discovery and collaborative partnerships in drug development, Calico offers an inspiring environment to foster significant medical breakthroughs. Position Overview: As a Medical Director/Senior Medical Director at Calico, you will report directly to the Head of Clinical Sciences. Your primary focus will be on providing strategic insights into the translational and clinical development of projects aimed at enhancing human health span through a better understanding of aging and age-related diseases, with a specific emphasis on neurologic and neuropsychiatric conditions. Key Responsibilities: Lead cross-functional teams to translate preclinical mechanistic data to clinical applications and develop translational biomarkers for innovative targets in neurologic and neuropsychiatric fields. Collaborate with research and drug development leaders both within and outside Calico to refine disease indication strategies for new targets. Utilize clinical expertise to guide the creation and application of preclinical models in partnership with discovery and biomarker scientists. Work closely with various drug development teams to shape new clinical programs throughout their lifecycle, particularly focusing on translational and early clinical development phases (Phase 0 through Phase 2). Design and implement experimental medicine studies to validate the mechanism of action for novel targets in neuropsychiatric disorders. Formulate and execute early clinical development strategies to establish proof of concept across various neuropsychiatric indications. Contribute scientific and medical knowledge for protocols, Investigator Brochures, Clinical Study reports, regulatory submissions, and other vital documents.

Join Artech Information Systems LLC as a Scientist. We are looking for a dedicated and innovative professional to contribute to our research and development team. In this role, you will engage in scientific research, drive experiments, and analyze data to support ongoing projects.

Cellares is on the lookout for an innovative and dynamic Information Security Lead to become the cornerstone of our Information Security program. As the inaugural security hire, you will play a pivotal role in shaping our InfoSec strategy while also engaging in hands-on technical execution. Your primary responsibility will be to enhance and strengthen our security posture, lead a diverse team across various locations, and ensure compliance with essential regulatory standards, including 21 CFR Part 11, SOC 2, and ISO 27001. This multidisciplinary role requires collaboration with multiple departments to drive policy and governance initiatives. Ideal candidates thrive in a fast-paced, mission-driven environment and are ready to embrace a variety of challenges as Cellares expands.

About Xaira Therapeutics Xaira Therapeutics is a biotech startup focused on using AI to transform drug discovery and development. The team builds generative AI models to design new protein and antibody therapeutics, especially for molecular targets that have been hard to address in the past. Xaira also develops foundation models for biological and disease understanding, which support better target identification and patient stratification. The company operates from the San Francisco Bay Area, Seattle, and London. Role Overview: Vice President of Information Technology Xaira is committed to becoming a fully AI-integrated biotech company. The Vice President of Information Technology will serve as the senior IT leader, responsible for driving the adoption and integration of AI across the organization. This role shapes the technology vision, oversees IT strategy, and ensures the infrastructure supports both scientific and operational goals. The VP will lead the IT team and manage all aspects of technology, from security and operations to long-term planning. Key Responsibilities Develop and execute IT strategy aligned with Xaira’s mission to accelerate drug discovery using AI Oversee IT infrastructure, security, and operations across multiple locations Lead and grow a high-performing IT team Champion the integration of AI tools and technologies throughout the company Ensure IT enables scientific teams to work efficiently and securely Foster accountability and measurable outcomes within the IT function Who Will Thrive in This Role This position suits an experienced technology leader who understands the central role IT plays in biotech. Success requires a strong vision for how IT can accelerate scientific progress and a hands-on approach to integrating AI into daily operations. The VP will help build the foundation that allows Xaira’s scientists and teams to deliver new medicines faster. Location Based in South San Francisco, California, United States.