Principal Scientist in Biologics Cell Line Development

Asimov builds tools for designing living systems, combining mammalian synthetic biology with software to support next-generation therapeutics. The Biologics Cell Line Development team in Boston, MA, is growing, and we're seeking a Principal Scientist to help lead our efforts in CHO-based cell line development for biologic therapeutics moving into clinical tr…

Asimov is seeking a highly skilled and experienced Senior Scientist/Principal Scientist in Biologics Cell Line Development to join our innovative team in Boston, MA. In this pivotal role, you will lead the development of high-yield mammalian cell lines for the production of biologics. You will collaborate closely with cross-functional teams to optimize production processes and ensure the successful translation of cell line development from research to clinical applications.

Join Cellular Intelligence as a Senior/Principal Machine Learning Researcher!At Cellular Intelligence, formerly known as Somite AI, we strive to revolutionize stem cell biology by creating AI foundational models that facilitate the development of innovative cell therapies on a large scale.Our comprehensive approach allows us to generate data at a cost efficiency of 1,000 times lower than traditional methods, while training large-scale models that possess unparalleled predictive capabilities. These models are pivotal in discovering, refining, and optimizing impactful applications in cell therapy.Our founding team boasts a wealth of experience, including AI entrepreneur Dr. Micha Breakstone, who successfully led Chorus.ai to a $575M acquisition, the Head of MIT's Fundamental AI Group, and a cadre of professors from Harvard Medical School and the University of Washington, comprising members of the National Academy of Sciences and Medicine. Based in Boston, we are excited to commence operations in January 2024 and have secured nearly $60 million in funding to date.

Axon Enterprise, Inc. develops devices and cloud-based software focused on public safety and justice. The company’s teams value collaboration, open communication, and diversity, aiming to create meaningful change while supporting employee growth and ownership. Role overview The Principal Data Scientist will join the Office of the Chief Accounting Officer in Boston. This position blends technical expertise with a strong understanding of finance and accounting. The main goal is to ensure Axon’s AI developers, process owners, decision-makers, and auditors have access to reliable, well-governed data that meets audit requirements. Main responsibilities Design and build data analytics tools and pipelines, dedicating about half of the workload to hands-on development. Apply AI to advance projects such as M&A integration, ERP rollouts, upstream data remediation, and SOX compliance. Work closely with teams in Controllership, Finance Operations, FP&A, Internal Audit, and Technology to support AI, automation, and audit readiness. Incorporate AI-driven development tools into daily tasks to improve productivity and outcomes. Location This position is based in Boston, Massachusetts, United States.

CarGurus, a leading online automotive marketplace, is seeking a Principal Data Scientist to join our innovative team in Boston, Massachusetts. As a Principal Data Scientist, you will leverage your expertise in data analysis, machine learning, and statistical modeling to drive insights that enhance our product offerings and improve user experiences. You will play a crucial role in shaping our data strategy and leading complex projects that impact the entire organization.

Join Formation Bio as a Principal Data Scientist, where you will play a pivotal role in shaping our data-driven strategies. We are seeking a highly skilled and innovative data scientist to lead complex projects and drive actionable insights from our data.In this position, you will collaborate with cross-functional teams, leveraging your expertise in statistical analysis, machine learning, and data visualization to inform decision-making and improve our products. Your contributions will directly impact our mission to harness data for groundbreaking advancements in biotechnology.

About Cellular IntelligenceCellular Intelligence, previously known as Somite AI, is an innovative venture-backed firm striving to redefine the realm of stem cell biology. We are on a mission to develop AI foundation models that will revolutionize human stem cell applications and promote scalable novel cell therapies.Our comprehensive approach involves generating data at unprecedentedly low costs, training large-scale models with unparalleled predictive capabilities, and employing these models to discover, refine, and optimize impactful applications in cell therapy.Our exceptional founding team includes seasoned AI entrepreneur Dr. Micha Breakstone (Chorus.ai, acquired for $575M), the Head of the Fundamental AI Group at MIT, who has pioneered foundational research on scaling laws, alongside three esteemed Harvard Medical School professors and members of the National Academy of Sciences/Medicine, including the Chair of the Genetics Department at HMS. Based in Boston and set to commence operations in January 2024, Cellular Intelligence has successfully raised nearly $60M to date.Core Values of Cellular Intelligence:Accountability: We show up fully, taking responsibility and committing to our goals.Urgency: We act swiftly and decisively, maintaining a proactive approach.Collaboration: We support one another with empathy and teamwork.Location: Boston, MA (onsite, full-time)About the Role:In the capacity of Senior Computational Biologist, you will be instrumental in developing pipelines, models, and conducting research on extensive single-cell datasets. This role is tailored for individuals passionate about large-scale transcriptomic data that will contribute to pioneering cell replacement technologies. You will operate at the intersection of developmental biological research, data science, and software development, aiding in single-cell and spatial transcriptomics analysis while translating scientific breakthroughs into advanced cell replacement therapies.

Cellular Intelligence (CI) is a pioneering AI-driven TechBio firm dedicated to constructing a universal foundation model of cell signaling. Our goal is to comprehend, forecast, and ultimately manipulate cellular behavior, thereby revolutionizing biology from a trial-and-error approach into a precise engineering discipline. With a full-stack methodology, we produce perturbation data at over 1,000 times the efficacy of traditional methods, capturing millions of time-resolved treatment combinations in each experiment. Our large-scale models are designed to generalize across various contexts, facilitating rational protocol design for regenerative medicine, specific drug effect prediction, and systematic disease modeling. The founding team includes notable AI entrepreneur Dr. Micha Breakstone, former Head of the Fundamental AI Group at MIT, and four esteemed professors from Harvard Medical School and the University of Washington, including the Chair of Genetics at Harvard, collectively holding five National Academy memberships. Based in Boston, CI has successfully raised over $60 million from investors such as Khosla Ventures, CZI, SciFi VC, and AMD Ventures, and is rapidly expanding its exceptional team.Core Values of Cellular IntelligenceAccountability - We show up fully accountable, committed, and ready to do whatever it takes.Urgency - We act swiftly, decisively, and proactively.Collaboration - We support each other through teamwork, helpfulness, and empathy.

The Principal Applications Developer serves as a senior technical leader, charged with the innovative design, effective delivery, and ongoing evolution of subsystem capabilities or cross-team initiatives. This pivotal role demands the ability to make informed technical decisions that integrate diverse perspectives while guiding teams toward robust, standards-compliant solutions. A strong focus is placed on maintaining architectural integrity, shaping technical strategies, and managing risks across multiple teams and functional areas.Key ResponsibilitiesSteer the end-to-end design and implementation of sophisticated subsystems or solution capabilities.Convert high-level objectives into actionable technical strategies that align with solution direction and business goals.Assess, select, and recommend appropriate technologies, tools, and frameworks, facilitating their integration.Analyze solution methodologies by weighing effort, risk, quality, operability, and sustainability.Independently or collaboratively deliver software projects of substantial scope and complexity.Proactively identify and manage cross-system dependencies and architectural risks.Provide expert technical leadership throughout planning, execution, and resolution of critical challenges.Mentor developers throughout the software delivery lifecycle, guiding thoughtful technical decisions.Articulate technical perspectives in discussions with senior stakeholders, both internal and external.Contribute independently to engagement with customers and industry-related initiatives.

The Single Cell Core (SCC) at Harvard Medical School is on the lookout for a Research Core Scientist to enhance our team. The ideal candidate will partner closely with the SCC Director to master single-cell RNA-sequencing and spatial transcriptomics techniques. This role involves executing experiments, working collaboratively with researchers to maximize the utility of valuable data derived from rare samples, and optimizing and validating novel technologies across a diverse range of genomics workflows. We seek an innovative, detail-oriented individual with strong analytical skills and exceptional communication abilities, capable of presenting findings in group lab meetings and regional scientific conferences. This position offers a unique opportunity to engage with cutting-edge methodologies at the forefront of next-generation sequencing and spatial transcriptomics, while also providing valuable experience in project management and leadership.Key Responsibilities:Independently conduct intricate single-cell and spatial transcriptomics experiments using various technologies. Manage library preparation and quality control processes. Regularly update and report on experimental progress to users, collaborating with the Director to troubleshoot errors and enhance workflows.Work alongside researchers to design and implement complex experiments utilizing rare samples. As a leading expert in single-cell and spatial transcriptomics at HMS, assist in validating and refining experimental protocols to establish efficient custom workflows, while offering expertise during data analysis and interpretation.Provide training to faculty, trainees, and other staff members on single-cell and spatial transcriptomics instrumentation.Organize and lead promotional and outreach initiatives, including workshops and user group meetings.Oversee core maintenance tasks, including supply procurement, equipment upkeep, and database management. Perform additional duties as necessary, such as billing and administrative tasks.Physical Requirements: Must be able to lift up to 25 lbs.

Join Formlabs as a Materials Scientist specializing in photopolymer development, where you will play a critical role in advancing our innovative 3D printing technology. You will be responsible for researching, developing, and optimizing photopolymer materials to enhance product performance and application versatility. Collaborate with cross-functional teams to translate material science insights into practical solutions that drive product excellence.

Senior Coordinator, Biologics Commercial Planning9 MonthsBoston, MA - HybridThis role focuses primarily on Biologics Planning. We are seeking a skilled professional to manage and execute critical supply chain activities for a late-stage biologic program. Join us in expanding our portfolio and commercializing a pipeline of innovative therapies.The Senior Coordinator will be responsible for coordinating monthly biologics supply planning efforts, supporting the Sales & Operations Planning (S&OP) process, and establishing effective planning and execution systems while conducting various supply planning and inventory management tasks.The global supply chain activities include delivering a comprehensive monthly supply plan and collaborating with External Manufacturing to align materials and capacity needs for timely execution. Additionally, this role will oversee the testing and integration of processes and systems to optimize our supply chain efficiency.This position reports to the Senior Director of Biologics Commercial Supply Chain within the Supply Chain Management organization and the Biopharmaceutical Sciences and Manufacturing Operations (BSMO) division, located at our corporate headquarters in Boston, MA.

We are seeking a passionate and detail-oriented Associate Scientist / Bench Scientist to join our dynamic team in Boston. In this role, you will be responsible for conducting experiments, analyzing data, and contributing to innovative research projects that advance our scientific knowledge and product development.

At IonQ, we are pioneering the development of the world's most advanced full-stack quantum computer utilizing trapped-ion technology. Our mission is to transcend the limitations of classical physics and current supercomputing capabilities, ushering in a transformative era of computing. The potential of quantum computing to enhance every aspect of human life is immense, and IonQ's innovations are set to revolutionize fields including medicine, materials science, finance, artificial intelligence, machine learning, cryptography, and beyond. Join us at the forefront of this technological evolution.We are seeking a Senior Research Scientist specializing in quantum memory development. In this pivotal role, you will spearhead a cross-functional team dedicated to advancing IonQ's mission to construct the preeminent quantum computers capable of tackling the world's most intricate challenges.Your work will involve groundbreaking research in quantum memories tailored for extensive quantum networks and modular quantum computing architectures. Collaborating with a prestigious team of scientists and engineers, you will develop systems designed for rapid processing and storage of quantum information derived from photons, ultimately leading to the creation of scalable quantum computing solutions. Your contributions will range from innovative system design to operationalizing and expanding quantum memory systems that will serve as the foundation for the largest quantum computers globally.

Role Overview Harvard University seeks a Research Assistant III with experience in cell culture and blood clotting-on-chip technologies. This position supports research at the intersection of biomedical engineering and regenerative medicine.

Motional is on the lookout for a highly skilled Principal Engineer to join our Planning team. In this pivotal role, you will be responsible for designing innovative motion planning and control systems that ensure the safe, efficient, and comfortable operation of our autonomous fleet in intricate environments. We seek an individual with a strong background in advanced algorithm development and robust software engineering, committed to shaping production-ready autonomous vehicles. If you are passionate about autonomous driving and enjoy tackling real-world challenges in a dynamic field, we welcome your application.Key Responsibilities:Lead the research and development of groundbreaking algorithms and subsystems for motion planning within autonomous driving, enhancing the Operational Design Domain. This encompasses advanced search-based and geometry-driven methods, alongside decision-making under uncertainty, with a focus on probabilistic techniques.Oversee cross-functional initiatives to create or enhance interfaces aimed at solving complex problems.Continuously monitor system performance to pinpoint areas for enhancement and formulate technical strategies to address shortcomings.Guide cross-functional project teams to deliver comprehensive solutions, showcasing the ability to think beyond the planning system's limitations.Architect and integrate sophisticated motion planning and prediction algorithms, leading their assessment and optimization for real-world applications.Design and develop a resilient, scalable, and high-performance codebase that enables rapid exploration, prototyping, and thorough evaluation of new motion planning methodologies and algorithms.Facilitate technical collaboration and ensure seamless integration with upstream perception and prediction components, as well as downstream trajectory optimization, tracking, and control systems, guaranteeing optimal end-to-end system performance.Utilize your extensive software development and research expertise to mentor others in best software practices, fostering a culture of technical excellence.Mentor junior and senior team members, promoting a culture of product-focused engineering, rigorous research, and advanced development.

Join a dynamic team at Recorded Future, the world's leading and largest intelligence company, with over 1,000 intelligence professionals serving more than 1,900 clients globally!We are on the lookout for a Principal Software Engineer who will be instrumental in enhancing our Engineering team. You will be responsible for designing and scaling the data pipelines that fuel our Security Intelligence Graph. As a Principal Software Engineer, your role will involve working on both application code and infrastructure to efficiently collect, transform, and deliver structured threat data, which includes tracking malware infrastructure, phishing campaigns, spam networks, command-and-control systems, and more. You will be a key contributor in driving architectural improvements and ensuring our platform's scalability as it evolves.

COMPANY DESCRIPTION Abiologics, Inc. is an innovative, privately held biotechnology company dedicated to transforming biology through advanced therapeutic modalities. We are leading the charge in developing Synteins™, a groundbreaking class of macromolecular medicines propelled by cutting-edge synthetic and computational technologies. We are on the lookout for outstanding scientists who are fervent about pioneering therapeutic modality innovations within the biotechnology landscape. Founded within Flagship Pioneering’s venture creation engine, Abiologics has its roots alongside remarkable companies such as Moderna Therapeutics (NASDAQ: MRNA) and Generate Biomedicines. Since its inception in 2000, Flagship has nurtured over 100 scientific ventures, producing more than 500 patents and facilitating over 50 clinical trials for novel therapeutic agents. THE ROLE We invite applications for an experienced and driven Senior Scientist in Medicinal Chemistry, with a specialization in miniprotein and peptide drugs. The ideal candidate will be instrumental in the design, synthesis, and optimization of innovative miniprotein therapeutics known as Synteins™. This role provides a distinctive opportunity to guide a new drug modality from early-stage research all the way through clinical development. KEY RESPONSIBILITIES Independently plan, execute, interpret, and enhance Syntein structure-activity campaigns through hands-on laboratory engagement. Utilize modern peptide chemistry and conjugation techniques to expedite the optimization of miniprotein drug development. Collaborate with interdisciplinary teams, including computational chemistry, biology, and pharmacology, to ensure project success. Champion innovation at the bench-side, ensuring a seamless transition from concept to execution. Mentor and lead junior scientists, promoting a collaborative and dynamic laboratory environment. Contribute to patent applications and scientific publications, highlighting laboratory advancements.

Join the culinary team at Eataly Boston as a Line Cook, where you'll have the opportunity to create authentic Italian dishes using the finest ingredients. As a Line Cook, you will be responsible for the preparation, cooking, and presentation of a variety of menu items, ensuring the highest standards of quality and taste. This is a fantastic opportunity for anyone passionate about food and eager to learn in a vibrant and dynamic kitchen environment.

About the RoleJoin Parallel Fluidics as we innovate the infrastructure powering the future of life science tools. As the Principal Mechanical Engineer, you will spearhead our most vital engineering initiatives, establish benchmarks for technical excellence, and influence the processes that guide our product development and manufacturing. We seek an experienced engineering leader with extensive knowledge in electromechanical system design, design for manufacturing, and automation. If you are passionate about making a significant impact by transforming groundbreaking products from concept to production in a fast-paced startup environment, we encourage you to apply.Key ResponsibilitiesEngineering LeadershipAct as the principal architect of the engineering processes at Parallel Fluidics.Lead critical engineering projects that align with our mission.Serve as a technical expert for various internal projects.Identify and implement improvements to our engineering systems and tools.Mentor junior and senior engineers across various disciplines.Provide progress reports and insights to company leadership.Product DevelopmentOversee the transition of Parallel’s next-generation hardware products from concept to scalable production.Identify and evaluate potential high-volume manufacturing partners.Facilitate the transfer of high-volume products from in-house production to third-party manufacturers.Manufacturing SystemsIdentify opportunities to enhance our in-house designed manufacturing equipment.Design experiments and testing methods to optimize manufacturing processes.Collaborate with the manufacturing team to pinpoint gaps and explore improvement opportunities.