Senior Safety Scientist

Revolution Medicines develops targeted therapies for patients with RAS-addicted cancers. The company’s pipeline includes several RAS(ON) inhibitors currently in clinical development, such as Daraxonrasib (RMC-6236), Elironrasib (RMC-6291), Zoldonrasib (RMC-9805), and RMC-5127. The team is dedicated to advancing treatments for cancers driven by mutations in t…

Revolution Medicines, Inc. seeks a Safety Scientist based in Redwood City, California. This role centers on supporting the safety and effectiveness of therapies under development. The Safety Scientist works with colleagues from various disciplines to review safety data, conduct evaluations, and assist with regulatory filings. What you will do Work with internal teams to assess and monitor safety profiles of therapies in development. Analyze safety data from both clinical and preclinical studies. Help prepare documents needed for regulatory submissions. Role impact This position plays a part in shaping new therapies and influencing the future of medicine by ensuring careful safety evaluation and strong collaboration across teams.

Role overview The Senior Manager, Global Patient Safety Operations at Revolution Medicines plays a central role in protecting patient health and ensuring compliance with regulatory requirements. Based in Redwood City, California, this position leads efforts to monitor and improve patient safety practices across international operations. The Senior Manager guides a team focused on upholding safety standards and supporting the company’s mission to deliver safe therapies. What you will do Lead and mentor a team dedicated to patient safety operations on a global scale. Oversee processes that monitor patient safety and maintain compliance with regulatory standards. Collaborate with other departments to advance initiatives that safeguard patients and promote better outcomes. Requirements Experience leading teams in patient safety or related operations. Understanding of regulatory requirements in the biopharmaceutical sector. Strong cross-functional collaboration skills.

Join our innovative team at Adverum Biotechnologies, Inc. as a Clinical Scientist/Senior on a contract basis. You will play a pivotal role in designing and implementing clinical trials, analyzing data, and collaborating with cross-functional teams to advance our gene therapy products. Your expertise will contribute to impactful research that aims to transform patient care and improve outcomes.

Join Revolution Medicines as a Senior Scientist I in Computational Chemistry, where you will play a pivotal role in advancing our drug discovery efforts. As part of our dynamic and innovative team, you will leverage your expertise in computational approaches to support the design and optimization of small molecules. Collaborate with cross-functional teams to drive projects from concept through to preclinical development, contributing to our mission of transforming the lives of patients with cancer.

We are seeking an experienced and driven Senior Scientist in Downstream Process Development to join our dynamic team on a contract basis. In this role, you will be responsible for developing and optimizing downstream processes for biologics production, focusing on purification and formulation. Your expertise will play a crucial role in advancing our innovative therapies to improve patient outcomes.

Join Revolution Medicines as a Senior Scientist I in Analytical Development, where you will play a pivotal role in advancing our innovative therapeutics. This position offers an exciting opportunity to contribute to the development of cutting-edge analytical methods and techniques that are crucial for our drug development pipeline. You will collaborate with cross-functional teams to ensure the successful delivery of high-quality data and analytical support.

Revolution Medicines is seeking a highly motivated and experienced Senior Scientist I for our Clinical Biomarker Development team. In this pivotal role, you will be responsible for the design, execution, and interpretation of biomarker studies aimed at supporting clinical trials. You will work closely with cross-functional teams to advance our innovative therapies and contribute to our mission of transforming the lives of patients with cancer.

Revolution Medicines is seeking a talented and motivated Senior Scientist I to join our Clinical Biomarker Development team. In this role, you will contribute to the advancement of innovative therapies by developing and validating biomarkers that support clinical decision-making. You will have the opportunity to work in a collaborative environment, leveraging cutting-edge technologies and methodologies to drive impactful results.

Revolution Medicines, based in Redwood City, California, develops targeted therapies for patients with RAS-addicted cancers. The company’s pipeline includes several RAS(ON) inhibitors, each designed to address specific oncogenic RAS protein variants. Clinical candidates such as daraxonrasib (RMC-6236), elironrasib (RMC-6291), zoldonrasib (RMC-9805), and RMC-5127 are in development, all focused on improving outcomes for patients with RAS pathway mutations. Role overview The Senior Director of Global Patient Safety Science leads safety science and pharmacovigilance across all products in the Revolution Medicines portfolio. This position shapes safety oversight and sets strategic direction for both early and late-stage development. The role sits within the Global Patient Safety team and may include direct reports, depending on program assignments. The Senior Director guides multiple or complex development programs and works closely with cross-functional teams to deliver thorough safety assessments and risk management plans. What you will do Oversee safety surveillance and risk management activities, including medical review of Individual Case Safety Reports (ICSRs), routine safety data evaluations, and scientific literature reviews. Contribute to safety signal assessments and address inquiries from regulatory authorities. Provide medical safety expertise for the design and execution of pharmacoepidemiology and observational studies. Plan and interpret safety data, preparing and presenting comprehensive summaries to internal and external stakeholders. Develop in-depth knowledge of assigned products’ safety profiles, considering disease context, competitor data, and mechanisms of action. Remain accountable for benefit-risk safety profiles throughout the product lifecycle.

Join us in creating a safer world, one incident at a time.At Ambient.ai, we are pioneering a state-of-the-art AI-driven physical security platform that empowers leading enterprises to minimize risk, enhance operational efficiency, and extract vital insights. Our innovative solutions are trusted by seven of the top 10 U.S. technology companies and numerous Fortune 500 organizations to modernize their security infrastructure.Our advanced AI and computer vision technology seamlessly integrates with existing camera and sensor systems, facilitating real-time monitoring and proactive threat detection. By reducing false alarms by more than 95%, we enable security teams to concentrate on genuine threats and take preventive measures before incidents occur.Founded in 2017 and supported by industry leaders such as Andreessen Horowitz, Y Combinator, and Allegion Ventures, Ambient.ai is a Series B company committed to making every security incident preventable.Eager to learn more? Connect with us on LinkedIn and YouTubeAbout the Role:We are seeking a Senior Applied Research Scientist to develop the next generation of foundation models tailored for computer vision. You will be part of a dynamic team responsible for creating multimodal models that achieve state-of-the-art performance on real-world vision benchmarks. This role requires ownership over the entire model development lifecycle, from pre-training and fine-tuning on image-language datasets to implementing distillation and compression techniques for deployment. This hands-on, cross-functional position will significantly contribute to our mission of preventing security incidents.Key Responsibilities:Develop & Optimize Vision-Language Models: Design and refine transformer-based models to interpret images, videos, and text, ensuring real-time inference performance.Pre-training & Fine-tuning: Manage the complete training pipeline, from pre-training on image-text data to fine-tuning for Ambient.ai’s specific security needs.Model Compression & Optimization: Utilize techniques such as distillation, quantization, and pruning to enhance model efficiency and reduce deployment latency.Innovate with Open-Source: Leverage and extend cutting-edge open-source models. Prototype new architectures and training methodologies to propel Ambient.ai’s multimodal AI advancements.

Revolution Medicines, Inc. is hiring a Senior Manager of Global Patient Safety Operations to join the team in Redwood City, California. This leadership role centers on guiding patient safety operations and maintaining regulatory compliance across the organization’s global activities. What you will do Direct patient safety operations on a global scale, ensuring all processes meet regulatory requirements. Champion initiatives that strengthen a culture of safety and vigilance throughout the company. Collaborate with cross-functional teams to support and enhance patient outcomes. Location This role is based in Redwood City, California, United States.

Join Adverum Biotechnologies, Inc. as a Senior Scientist specializing in Drug Product development. In this pivotal role, you will leverage your expertise in pharmaceutical sciences to contribute to our mission of advancing innovative gene therapies. You will collaborate closely with cross-functional teams to drive the formulation and development of high-quality drug products, ensuring compliance with regulatory standards and industry best practices.

Join Poshmark, a leading social commerce platform, as a Staff Data Scientist. In this pivotal role, you will leverage your expertise in data analysis and machine learning to drive insights and innovations that enhance our platform and user experience. You'll work collaboratively with cross-functional teams to develop robust models, implement data-driven strategies, and contribute to the evolution of our analytics capabilities.

At Retro, we are pioneering innovative therapies that target age-related diseases. Our focus is on cellular reprogramming and autophagy to restore cell and tissue vitality, aiming to add a decade to the healthy human lifespan.We are assembling a passionate, mission-driven team of talented individuals who thrive in our dynamic startup environment characterized by rapid innovation, transparency, and adaptability.We are on the lookout for an ambitious Scientist specializing in Genomics to develop and optimize platforms that facilitate the discovery of therapies aimed at rejuvenating cellular and tissue functions. You will manage sequencing workflows from start to finish, collaborating closely with automation and computational scientists to scale your innovations and generate crucial data for our advanced models.

Join our dynamic team as a Senior Research Scientist where your expertise in bioanalytical assays will be pivotal in supporting our discovery biologics portfolio. You will be responsible for the design and development of bioanalytical assays and conducting thorough sample analyses for various study samples. Utilizing cutting-edge platforms such as Gyrolab, MSD, and ELISA, you will play a crucial role in pharmacokinetic (PK) studies focused on large molecule projects.Your role will require you to independently execute complex experiments while maintaining meticulous attention to detail and comprehensive documentation. Strong written and verbal communication skills are essential to effectively convey findings and collaborate with team members.

Join Revolution Medicines as a Senior Machine Learning Scientist specializing in Drug Discovery Analytics. In this pivotal role, you will leverage advanced machine learning techniques to enhance our drug discovery processes, collaborating closely with cross-functional teams to drive innovative solutions in biotechnology.

About the RoleCharacter.AI is seeking a passionate and innovative Software Engineer to join our Safety Engineering team! In this pivotal role, you will collaborate closely with Product, Design, and Trust and Safety operations teams to develop tools and product features that promote a safe, transparent, and engaging user experience. You'll be instrumental in crafting groundbreaking solutions to the unique challenges associated with human-to-AI interaction, applying your technical skills to help shape industry best practices in this evolving field.Key ResponsibilitiesDesign and implement the user interface for our Trust and Safety systems, balancing risk reduction, user experience enhancement, and platform reliability across various features to deliver an exceptional user experience.Gain a deep understanding of our users and their behaviors to create innovative technical solutions that encourage positive interactions on our platform.Partner with other product teams to co-create modular and scalable safety design systems that ensure all product features can be launched safely while maintaining a high launch velocity.Work collaboratively with the Trust & Safety team to understand moderation workflows and develop tools that enhance their decision-making capabilities. Evaluate and integrate third-party solutions when necessary.Collaborate with engineers and Trust & Safety stakeholders to design interfaces and interaction models that incorporate AI-assisted moderation, facilitating effective human-AI collaboration.Utilize user data and insights to enhance our core LLM and other models. Develop frontend systems that visualize the feedback loops between moderation actions and AI training, ensuring that critical data insights are surfaced to support safe and positive user experiences across the platform.

About DexterityAt Dexterity, we are passionate about the transformational potential of robotics. Our innovative technology empowers individuals to engage in creative and complex problem-solving tasks, allowing robots to take on repetitive and physically demanding work. We are initially focusing on warehouse automation, where the demand for smarter and more resilient supply chains significantly impacts millions of lives and businesses globally.Dexterity’s advanced robotics systems are designed to pick, move, pack, and collaborate with a level of skill, awareness, and learning akin to humans. Our solutions are software-focused and hardware-independent, having already processed over 15 million items in production. Our customer-centric approach drives every decision we make, ensuring that we empower our clients to achieve more with our robotic solutions than they ever imagined possible.As one of the fastest-growing firms in the robotics sector, Dexterity is proudly supported by prestigious investors including Kleiner Perkins, Lightspeed Venture Partners, and Obvious Ventures. Our diverse and multidisciplinary team thrives on a culture of passion, trust, and commitment. Join us at Dexterity and contribute to turning intelligent robots into a reality!About the RoleIn the capacity of a Senior Functional Safety Engineer, you will spearhead the design and verification of functional safety in our robotic systems while ensuring compliance with regulations in North America, Europe, and Japan. We are seeking a candidate with a comprehensive understanding of relevant industry standards, who can harmonize innovative engineering practices with established design and safety principles in this burgeoning field. Your contributions will be pivotal to Dexterity’s growth and global reach, as you design and implement safe and compliant solutions.

Join us at Retro, a pioneering leader in the field of regenerative medicine, as we seek a dedicated Scientist specializing in iPSC Differentiation with a focus on Hematopoiesis. In this role, you will harness your expertise to drive innovative research and contribute to our mission of advancing human health through cutting-edge science.