Director of Drug Product Development

JOB SUMMARYIambic Therapeutics is actively seeking a Director of Drug Product Development to spearhead formulation and process development for small molecule programs, guiding them from late discovery/IND-enabling stages through clinical phases, with a clear trajectory towards later-stage development, global registrations, and commercialization. This pivotal…

Role Overview Iambic Therapeutics is seeking an Associate Director or Director of Biology to advance oncology drug discovery efforts at our San Diego headquarters. This leader will shape scientific strategy and guide teams through every stage, from hit identification to IND submission. The position requires a strong record of leading oncology drug discovery programs and experience collaborating across disciplines, including Chemistry, DMPK, Safety, and Computational teams. Impact and Scope Work directly with computational and machine learning scientists to apply AI/ML tools that support data interpretation, hypothesis generation, and decision-making in biology workflows. This role plays a central part in steering portfolio strategy and advancing key programs. Key Responsibilities Program Leadership: Design and oversee biology strategies that align with medicinal chemistry and translational goals across all discovery phases, including hit-to-lead, lead optimization, candidate selection, and IND-enabling studies. Cross-Functional Integration: Lead or co-chair initiatives that coordinate assay design with SAR hypotheses, DMPK/PD needs, and safety or translational biomarker requirements. Collaboration Leadership: Drive major scientific partnerships, both internal and external, ensuring effective data sharing and strategic alignment. Assay Strategy and Data Integrity: Develop, validate, and supervise in vitro and ex vivo assays (such as signaling, binding, trafficking, imaging, and mechanism of action) to evaluate potency, selectivity, and efficacy. Establish acceptance criteria, controls, and quality standards. External Execution: Oversee and mentor CROs and partners, define statements of work, manage timelines and budgets, and ensure adherence to internal SOPs and GLP-adjacent practices. People Leadership and Development: Build and support a team of scientists and associates by setting goals, offering feedback, and fostering professional growth. Decision-Making: Lead stage-gate reviews, maintain risk registers, develop mitigation plans, and prepare decision memos for leadership and governance bodies.

Join Iambic Therapeutics as the Associate Director of Drug Metabolism and Pharmacokinetics (DMPK), where you will drive innovative DMPK strategies throughout our discovery and preclinical development programs. Your expertise will be pivotal in designing and implementing integrated ADME/PK strategies that facilitate program advancement and inform critical decision-making for IND submissions.In this role, you will represent DMPK on cross-functional teams, collaborating closely with our internal scientists and external CRO partners to plan, execute, and interpret studies. This position is based at our San Diego Headquarters, where you will be at the forefront of advancing therapeutic candidates. KEY RESPONSIBILITIESDesign and implement DMPK strategies to propel discovery and development initiatives.Plan, execute, and interpret DMPK studies to support the progression of therapeutic candidates during discovery and early development stages.Collaborate with diverse teams including medicinal chemistry, biology, CMC, and clinical to provide DMPK insights that inform project decisions.Utilize AI-driven tools and computational methods to enhance DMPK strategy, facilitate predictive ADME/PK assessments, and expedite data-driven decision-making.Address ADME/PK-related challenges during lead optimization.Oversee external ADME/PK and PK/PD studies, coordinating with CROs and reviewing data.Prepare DMPK summaries and regulatory submission documentation (e.g., IND, IB).Interpret ADME/PK data, communicating findings and recommendations effectively to project teams.Stay abreast of advancements in DMPK, PBPK, PK/PD, and regulatory guidelines.Ensure that all studies comply with relevant regulatory and quality standards.

Join Sobi as a pivotal leader in our Manufacturing Science and Technology team. As the Drug Product Lead, you will spearhead the development and implementation of innovative drug manufacturing processes, ensuring high-quality standards and compliance with regulatory requirements. This role is integral to advancing our product pipeline and enhancing operational efficiencies.

Join a thriving start-up environment! As a key member of our dynamic team, you'll have the chance to diversify your skills and enjoy significant opportunities for financial and professional advancement.What makes us unique? We are targeting some of the most pressing challenges in biology today, assembling an exceptional team of engineers, scientists, and problem solvers dedicated to innovating the next generation of technologies that will decode the complexities of biological systems.Embrace this exceptional opportunity to contribute to a promising start-up while collaborating with talented, down-to-earth individuals.Reporting to the Head of Operations & Corporate/Business Development, the Director of Corporate & Business Development will spearhead our strategic initiatives and partnership efforts within the Cell & Gene Therapy and Drug Discovery sectors. This pivotal role will influence how Cellanome's technologies and products are marketed and sold to BioPharma clients, including CDMOs. The ideal candidate will blend in-depth technical knowledge with a proven track record in business development to identify, evaluate, and finalize strategic deals that propel our growth. Key responsibilities include:Sourcing, evaluating, and negotiating development deals, licensing agreements, and strategic partnerships with pharmaceutical, biotech, and CDMO firms in the Cell & Gene Therapy and Drug Discovery sectors.Building and managing consortiums to promote collaborative research initiatives and multi-partner programs utilizing Cellanome's technology.Collaborating with internal teams to refine product offerings that leverage Cellanome's technology platform to meet evolving market demands.Establishing and maintaining a strong pipeline of qualified opportunities and driving deals to successful closure.Gathering market intelligence and competitive insights to guide product strategy and positioning.Representing Cellanome at industry conferences and client meetings.

At Art of Problem Solving, we are revolutionizing the educational journey for families and students, transforming the fragmented experiences of discovery and long-term learning into a seamless, unified adventure. As the Director of Product Design, you will spearhead this transformation, enhancing both the customer journey and the learning experience. You will influence how families discover and choose AoPS, as well as how students interact with and progress through our comprehensive curriculum. Additionally, you will play a crucial role in integrating our dynamic brand identity into our products, ensuring it resonates not just visually, but is fundamentally woven into the functionality and feel of our learning tools. This leadership position is designed for an experienced player-coach who can define strategic directions, elevate design standards, and actively participate in team design efforts through constructive critique, mentorship, design workshops, and the exploration of innovative tools and technologies that enhance our building processes. Key Responsibilities: Establish and drive a cohesive design vision across discovery, enrollment, and learning, harmonizing fragmented products and journeys into an integrated system. Translate AoPS's evolving brand identity into engaging product experiences, ensuring our products effectively support the learning process. Cultivate collaboration between Product, Design, and Engineering teams by enhancing workflows and adopting contemporary tools (including AI) to boost efficiency, quality, and teamwork. Collaborate closely with academic teams to ensure pedagogical insights significantly inform the design of learning experiences. Develop and implement design systems, standards, and practices to promote consistency, quality, and productivity across teams. Lead and nurture a robust design team by recruiting, mentoring, and developing designers, fostering a culture of thoughtful critique and high standards.

At Genesis Molecular AI, we are creating an elite team of experts in computational chemistry to transform the landscape of drug discovery through advanced machine learning and biophysical simulations. We invite a Senior Computational Aided Drug Discovery (CADD) Scientist to join us in our mission, collaborating closely with scientists in our advanced wet lab and our distributed teams in computational chemistry across the United States.Key ResponsibilitiesEmploy a mix of industry-standard and proprietary AI-driven CADD tools to steer small molecule drug discovery initiatives across a diverse array of targets, including innovative targets with limited chemical history.Utilize techniques such as virtual screening, molecular simulations, and ADMET prediction to facilitate critical decision-making during drug discovery.Work closely with medicinal chemists on molecular design and the creation of tailored computational methodologies for specific projects.Serve as a liaison across teams, effectively bridging communication between our computational and medicinal chemistry departments to ensure smooth information exchange and collaborative strategies.Thrive in a fast-paced environment that encourages innovation and rapid iteration.QualificationsPhD in Computational Chemistry, Structural Biology, or a related discipline. Candidates with a PhD in organic or medicinal chemistry and substantial laboratory experience transitioning into industry roles in CADD are also encouraged to apply.Extensive knowledge of structure-based drug design and protein-ligand interactions.Expertise in using industry-standard CADD tools, including MOE, PyMOL, and Schrodinger Suite.A minimum of 2 years of experience in the pharmaceutical or biotech industry as a CADD scientist, with practical involvement in active drug discovery projects.While onsite presence at our San Diego lab is preferred for collaboration, we are open to considering remote team members as well.What We OfferAttractive SalaryComprehensive Health Care Plans (Medical, Dental, and Vision fully covered for employees)An opportunity to work in a pioneering environment with the latest technologies in drug discovery.

Join ServiceNow as a Product Marketing Director in beautiful San Diego. In this pivotal leadership role, you will be responsible for crafting and executing product marketing strategies that resonate with our customers and drive business growth. You will collaborate closely with cross-functional teams to ensure alignment between product development and market needs, leveraging your deep understanding of the industry to position our solutions effectively.Your innovative mindset and strategic vision will guide our marketing initiatives, ensuring they are data-driven and customer-focused. You will also lead a talented team, fostering a culture of creativity and excellence.

Location Requirement:This position may be based on either the U.S. West Coast (ideally near San Diego, CA) or the East Coast (ideally near Raleigh, NC or Boston, MA). The role requires periodic travel between both locations to support cross-site collaboration and business needs.The CMC & Manufacturing, Science and Technology Drug Substance Lead will be tasked with:Serving as an experienced subject matter expert (SME) and process owner for the synthesis of small molecules utilized in oral dosage forms.Leading technical workstreams for manufacturing process transfers from development to commercial sites, overseeing scale-up activities, process validations, and managing the manufacturing of Drug Substance small molecules at external manufacturers for clinical and commercial projects.Collaborating effectively with external manufacturing partners and managing all technical aspects of drug substance synthesis (GMP and non-GMP).Overseeing internal activities related to external manufacturing, including process change assessments, major/critical deviations, risk assessments, and CAPAs.Reviewing and supervising the design, execution, and documentation of DS-related technical studies, as well as process and equipment qualifications and validations.Writing and reviewing pertinent sections in registration files, variations, and market expansions.Issuing, reviewing, and approving internal and external SOPs, ensuring compliance with external manufacturer instructions.Contributing to the establishment of new analytical specifications and stability programs, and reviewing modifications thereof.Assisting in the evaluation of new Drug Substance small molecules and oral dosage form contract manufacturers, participating in the development of supply and quality agreements.Staying informed about modern synthetic organic chemistry methodologies, understanding advancements, and introducing new technologies for process innovation and improvements in cost or yield.

As the Director of Product, Customer Experience at Art of Problem Solving, you will lead our initiatives to enhance customer satisfaction and engagement through innovative product solutions. Your strategic vision will drive the development and optimization of user experience across all platforms.You will collaborate with cross-functional teams, including marketing, sales, and customer support, to ensure our products meet the evolving needs of our users. This role requires a deep understanding of customer behavior, analytics, and product management.

We are seeking a highly skilled Senior Director of Medicinal Chemistry to join our innovative team at Genesis Molecular AI. In this pivotal role, you will leverage our cutting-edge platform to spearhead medicinal chemistry initiatives that drive drug discovery from Hit Identification to candidate nomination. You will be a key collaborator and leader in multidisciplinary drug discovery projects, shaping the medicinal chemistry strategy for each project. As a recognized leader in medicinal chemistry, you will possess exceptional communication skills, facilitating collaboration with both internal teams and external partners.Key ResponsibilitiesDevelop and implement medicinal chemistry strategies utilizing the Genesis platform to effectively manage drug discovery programs from Hit ID through to candidate nomination.Apply Structure-Based Drug Design (SBDD) principles, optimize physicochemical properties, and interpret in vitro and in vivo ADME/PK/Toxicology data to advance projects.Employ data visualization software and metrics-driven analysis to formulate medicinal chemistry hypotheses and prioritize project strategies.Engage and collaborate with industry partners on various drug discovery projects.Work closely with other drug discovery disciplines, including biology, DMPK, software engineering, and computational chemistry, to foster hypothesis-driven decisions and enhance platform capabilities.Maintain regular communication and engagement with project teams and management to ensure alignment and progress.Mentor and guide internal chemists and other scientific professionals on medicinal chemistry best practices.

Who We AreAt Stealth Fintech, we are on a transformative journey to reshape B2B payments. As a well-funded, innovative startup operating in stealth mode, we are dedicated to crafting advanced solutions that will redefine the financial landscape for businesses. If you are passionate about addressing significant challenges and making a substantial impact from the outset, we would love to connect with you.Role OverviewWe are seeking an experienced Senior Director of Product and Growth Marketing to join our dynamic Sales and Marketing team. In this pivotal role, you will lead product marketing efforts and drive demand generation. This is a unique opportunity to shape the go-to-market strategy of our fintech platform at a critical juncture, reporting directly to the Chief Sales Officer.Your ResponsibilitiesDevelop and execute a comprehensive integrated marketing strategy that aligns with our business goals, encompassing brand, product marketing, and demand generation.Implement initial priorities within the first year to establish our core value proposition, messaging, high-impact content assets, and a website that resonates with our target audience, aiming to generate $5 million in pipeline within the first year.Manage the marketing budget and performance metrics; intelligently allocate resources to optimize return and pipeline results.Lead demand generation initiatives, including events, while continuously refining strategies based on data analysis.Oversee hands-on execution of marketing materials, external communications, and web presence.Ideal Qualifications7+ years of experience in B2B marketing with demonstrated success in product marketing and demand generation.In-depth knowledge of demand generation strategies, performance marketing, account-based marketing (ABM), and funnel analytics.Proven ability to create compelling product narratives for executive-level audiences.Exceptional verbal and written communication skills, capable of thriving in a fast-paced, collaborative environment.

Join Janux Therapeutics as the Senior Executive Director of Clinical Pharmacology, where you will play a pivotal role in shaping our clinical development programs. We are looking for a proactive, data-driven leader who excels in the design, analysis, and interpretation of clinical pharmacology strategies. This position is perfect for a scientific innovator who enjoys working closely with data to ensure exemplary pharmacokinetic (PK) analyses and facilitates informed decision-making regarding dosage selection and regulatory submissions.In this role, you will prioritize executional excellence and strategic alignment within the team, ensuring that all deliverables meet the highest standards of scientific rigor.

Positive Development seeks a Child Development Specialist in San Diego, CA to support children’s growth and learning. This position centers on building strong relationships with families and educators, working together to create environments where children can thrive both academically and emotionally. Role overview The Child Development Specialist will contribute expertise to shape and carry out programs tailored to each child’s needs. Collaboration is key: expect to partner with others to develop strategies that encourage healthy development and positive learning experiences. What you will do Work directly with children, families, and educators to support learning and emotional well-being Help design and implement individualized programs for child development Create supportive, inclusive environments that respond to each child’s strengths and challenges

Role Overview iambic therapeutics seeks a Director or Senior Director of Medicinal Chemistry to guide drug discovery efforts from our San Diego headquarters. This leadership role calls for deep experience in medicinal chemistry and a strong record of moving drug discovery programs forward. The position sits at the center of scientific strategy and team leadership within a multidisciplinary setting. What You Will Do Oversee drug discovery projects from early-stage concepts through key milestones Lead, mentor, and develop a team of medicinal chemists Coordinate resources across internal teams and external partners Work closely with groups specializing in automated experimentation, machine learning-based molecular design, property prediction, and bioassay data analysis Location This role is based onsite at our San Diego headquarters.

Quantum-Si is actively looking for a results-driven Director of Business Development and Strategic Alliances who will play a pivotal role in establishing and operationalizing partnerships that broaden our ecosystem. This position is crucial for unlocking new workflows and applications, thereby accelerating the commercial uptake of our cutting-edge proteomics platform. The incumbent will oversee the entire partnership lifecycle—from scoping and initiation to cross-functional execution, governance, and value delivery. The ideal candidate is a proactive operator, adept at managing complex internal and external projects, delivering quantifiable results, and ready to take on greater leadership responsibilities as they evolve within the organization.

Genesis Therapeutics is seeking an innovative and experienced Associate Director/Director of Medicinal Chemistry to join our dynamic team in San Diego, CA. In this leadership role, you will spearhead the design and optimization of novel therapeutic compounds, driving the discovery process from initial concept through to clinical candidates.The ideal candidate will have a robust background in medicinal chemistry and a proven track record of leading successful drug discovery projects. You will collaborate closely with cross-functional teams, fostering an environment of creativity and scientific excellence.

About UsAt Metropolis, we are leading the way in transforming how the real world interacts with technology. Our mission is to leverage artificial intelligence to create a responsive environment, pioneering the Recognition Economy where familiarity enhances accessibility, comfort, and a sense of belonging. We are reshaping everyday experiences, from parking to retail and hospitality, making them seamless and intuitive. Join us in building a future that feels both magical and instinctive.Your RoleWe are on the lookout for a strategic and energetic Director of Business Development to join our rapidly expanding team. In this pivotal role, you will take ownership of a regional territory, focusing on generating new business opportunities and negotiating impactful deals. This is a remarkable chance to contribute to Metropolis’s growth as we disrupt the parking industry and beyond, utilizing cutting-edge AI and computer vision technology. Your relationship-building expertise and network will be crucial in driving our mission forward.Your ResponsibilitiesManage the complete sales process in your designated territory (San Diego), from prospecting to negotiation and closing.Identify and cultivate new business opportunities through various lead generation strategies, including cold outreach and networking events.Employ a consultative approach to identify client pain points and develop tailored, solution-oriented proposals.Lead client presentations, including discovery sessions and proposal discussions.Establish and nurture relationships across key stakeholder groups.Collaborate cross-functionally with teams on underwriting and financial modeling.Work together with marketing, operations, and legal teams to align efforts with overarching business objectives.Track and manage pipeline development and sales performance metrics in CRM for continual improvement.Stay informed about industry trends and emerging technologies to shape business development strategies.Travel within the region to support clients and pursue new business opportunities as necessary.

Join Janux Therapeutics as the Senior Director of Business Development and Alliance Management, where you will spearhead strategic initiatives to discover, assess, and secure partnerships that enhance Janux's pipeline and platform capabilities. This pivotal role merges business development acumen with alliance management to influence corporate strategy and uphold a competitive advantage in the dynamic biotech sector.

Millennium Health LLC is a highly regarded specialty laboratory with over a decade of expertise in medication monitoring and drug testing services. We empower healthcare professionals to effectively monitor both the use and misuse of prescription medications and illicit substances. Our testing solutions provide clinicians with objective insights into patients' recent drug usage, enhancing the effectiveness of treatment plans.We are seeking a Clinical Scientist who will take the lead in developing clinical LC-MS/MS assays. This role involves independently conducting original scientific research and creating innovative analytical technologies while managing project resources and timelines effectively.The responsibilities of this position include, but are not limited to: Acting as a technical leader to design, develop, and validate high-quality LC-MS/MS assays/products/technologies within established timelines. Providing formal and informal scientific mentoring to team members. Leveraging technical expertise to design experiments and independently contribute to multiple projects concurrently. Serving as a critical technical and scientific resource within the organization. Drafting, reviewing, and finalizing technical documentation essential for various stages of product development. Maintaining meticulous experimental records in compliance with company SOPs. Ensuring adherence to HIPAA, confidentiality, and compliance policies, procedures, and standards. Upholding administrative, physical, and technical cybersecurity controls. Consistent and reliable attendance is a must.