Executive Director of Discovery

Join Veracyte, a trailblazing company dedicated to revolutionizing cancer care for patients globally. At Veracyte, our employees contribute significantly to patient outcomes while thriving in a mission-driven culture. We embody the Veracyte way—a collaborative approach rooted in our values to empower clinicians with crucial insights for transformative patien…

Role Overview Iambic Therapeutics is seeking an Associate Director or Director of Biology to advance oncology drug discovery efforts at our San Diego headquarters. This leader will shape scientific strategy and guide teams through every stage, from hit identification to IND submission. The position requires a strong record of leading oncology drug discovery programs and experience collaborating across disciplines, including Chemistry, DMPK, Safety, and Computational teams. Impact and Scope Work directly with computational and machine learning scientists to apply AI/ML tools that support data interpretation, hypothesis generation, and decision-making in biology workflows. This role plays a central part in steering portfolio strategy and advancing key programs. Key Responsibilities Program Leadership: Design and oversee biology strategies that align with medicinal chemistry and translational goals across all discovery phases, including hit-to-lead, lead optimization, candidate selection, and IND-enabling studies. Cross-Functional Integration: Lead or co-chair initiatives that coordinate assay design with SAR hypotheses, DMPK/PD needs, and safety or translational biomarker requirements. Collaboration Leadership: Drive major scientific partnerships, both internal and external, ensuring effective data sharing and strategic alignment. Assay Strategy and Data Integrity: Develop, validate, and supervise in vitro and ex vivo assays (such as signaling, binding, trafficking, imaging, and mechanism of action) to evaluate potency, selectivity, and efficacy. Establish acceptance criteria, controls, and quality standards. External Execution: Oversee and mentor CROs and partners, define statements of work, manage timelines and budgets, and ensure adherence to internal SOPs and GLP-adjacent practices. People Leadership and Development: Build and support a team of scientists and associates by setting goals, offering feedback, and fostering professional growth. Decision-Making: Lead stage-gate reviews, maintain risk registers, develop mitigation plans, and prepare decision memos for leadership and governance bodies.

At Genesis Molecular AI, we are creating an elite team of experts in computational chemistry to transform the landscape of drug discovery through advanced machine learning and biophysical simulations. We invite a Senior Computational Aided Drug Discovery (CADD) Scientist to join us in our mission, collaborating closely with scientists in our advanced wet lab and our distributed teams in computational chemistry across the United States.Key ResponsibilitiesEmploy a mix of industry-standard and proprietary AI-driven CADD tools to steer small molecule drug discovery initiatives across a diverse array of targets, including innovative targets with limited chemical history.Utilize techniques such as virtual screening, molecular simulations, and ADMET prediction to facilitate critical decision-making during drug discovery.Work closely with medicinal chemists on molecular design and the creation of tailored computational methodologies for specific projects.Serve as a liaison across teams, effectively bridging communication between our computational and medicinal chemistry departments to ensure smooth information exchange and collaborative strategies.Thrive in a fast-paced environment that encourages innovation and rapid iteration.QualificationsPhD in Computational Chemistry, Structural Biology, or a related discipline. Candidates with a PhD in organic or medicinal chemistry and substantial laboratory experience transitioning into industry roles in CADD are also encouraged to apply.Extensive knowledge of structure-based drug design and protein-ligand interactions.Expertise in using industry-standard CADD tools, including MOE, PyMOL, and Schrodinger Suite.A minimum of 2 years of experience in the pharmaceutical or biotech industry as a CADD scientist, with practical involvement in active drug discovery projects.While onsite presence at our San Diego lab is preferred for collaboration, we are open to considering remote team members as well.What We OfferAttractive SalaryComprehensive Health Care Plans (Medical, Dental, and Vision fully covered for employees)An opportunity to work in a pioneering environment with the latest technologies in drug discovery.

About Acadia Pharmaceuticals Acadia Pharmaceuticals focuses on turning scientific discoveries into meaningful treatments for underserved communities affected by neurological and rare diseases. The company’s commercial portfolio includes the first and only FDA-approved therapies for Parkinson’s disease psychosis and Rett syndrome. Acadia continues to advance a diverse pipeline, with mid- and late-stage programs for Alzheimer’s disease psychosis and Lewy body dementia psychosis, as well as early-stage efforts aimed at additional unmet needs. The team is committed to making a real difference in patients’ lives. Location and Work Model This position may be based in San Diego, CA, San Francisco, CA, or Princeton, NJ. Acadia offers a hybrid work model. Role Overview The Executive Director of Translational Sciences leads the design and execution of disease and drug mechanism of action (MoA) studies that advance therapeutics through clinical development. This position requires deep expertise in translational sciences and hands-on experience in rare diseases. Strong leadership and mentoring skills are essential, as well as a thorough understanding of clinical biomarker development and the full drug development process from discovery through late-stage clinical trials. Success in this role depends on the ability to translate complex biological concepts and data into clear, actionable insights. The Executive Director must also demonstrate a record of effective cross-functional collaboration throughout the drug development process.

We are seeking a highly skilled Senior Director of Medicinal Chemistry to join our innovative team at Genesis Molecular AI. In this pivotal role, you will leverage our cutting-edge platform to spearhead medicinal chemistry initiatives that drive drug discovery from Hit Identification to candidate nomination. You will be a key collaborator and leader in multidisciplinary drug discovery projects, shaping the medicinal chemistry strategy for each project. As a recognized leader in medicinal chemistry, you will possess exceptional communication skills, facilitating collaboration with both internal teams and external partners.Key ResponsibilitiesDevelop and implement medicinal chemistry strategies utilizing the Genesis platform to effectively manage drug discovery programs from Hit ID through to candidate nomination.Apply Structure-Based Drug Design (SBDD) principles, optimize physicochemical properties, and interpret in vitro and in vivo ADME/PK/Toxicology data to advance projects.Employ data visualization software and metrics-driven analysis to formulate medicinal chemistry hypotheses and prioritize project strategies.Engage and collaborate with industry partners on various drug discovery projects.Work closely with other drug discovery disciplines, including biology, DMPK, software engineering, and computational chemistry, to foster hypothesis-driven decisions and enhance platform capabilities.Maintain regular communication and engagement with project teams and management to ensure alignment and progress.Mentor and guide internal chemists and other scientific professionals on medicinal chemistry best practices.

We are on the lookout for exceptional scientists to join our Discovery Machine Learning team at Iambic Therapeutics. This position will play a pivotal role in utilizing cutting-edge machine learning techniques to enhance our drug discovery initiatives. You will collaborate with drug discovery teams focused on developing innovative therapeutics for a variety of conditions. Your work will center around our leading machine learning models, such as Enchant, our multimodal transformer model designed for predicting drug-target interactions and molecular properties. This opportunity is based at our headquarters in San Diego.

Role Overview iambic therapeutics seeks a Director or Senior Director of Medicinal Chemistry to guide drug discovery efforts from our San Diego headquarters. This leadership role calls for deep experience in medicinal chemistry and a strong record of moving drug discovery programs forward. The position sits at the center of scientific strategy and team leadership within a multidisciplinary setting. What You Will Do Oversee drug discovery projects from early-stage concepts through key milestones Lead, mentor, and develop a team of medicinal chemists Coordinate resources across internal teams and external partners Work closely with groups specializing in automated experimentation, machine learning-based molecular design, property prediction, and bioassay data analysis Location This role is based onsite at our San Diego headquarters.

Genesis Therapeutics is seeking an innovative and experienced Associate Director/Director of Medicinal Chemistry to join our dynamic team in San Diego, CA. In this leadership role, you will spearhead the design and optimization of novel therapeutic compounds, driving the discovery process from initial concept through to clinical candidates.The ideal candidate will have a robust background in medicinal chemistry and a proven track record of leading successful drug discovery projects. You will collaborate closely with cross-functional teams, fostering an environment of creativity and scientific excellence.

Join Genesis Molecular AI as an Associate Director/Director of Medicinal Chemistry, where you will play a pivotal role in utilizing our cutting-edge AI platform to spearhead drug discovery initiatives, guiding projects from Hit Identification through to candidate nomination. Collaborate with multidisciplinary teams to shape the medicinal chemistry vision and drive innovative solutions in drug development.Key Responsibilities:Develop and implement medicinal chemistry strategies using the Genesis platform for drug discovery from Hit ID through to candidate nomination.Apply Structure-Based Drug Design (SBDD) methodologies, optimize physicochemical properties, and analyze in vitro and in vivo ADME/PK/Toxicology data to advance programs.Leverage data visualization tools and metrics to formulate medicinal chemistry hypotheses and prioritize approaches effectively.Foster communication and collaboration with industry partners on drug discovery initiatives.Engage with diverse drug discovery teams (biology, DMPK, software engineers, computational chemists) to drive data-driven decisions, enhance platform capabilities, and uphold scientific excellence.Maintain regular communication with project team members and management to ensure alignment and progress.

Join a thriving start-up environment! As a key member of our dynamic team, you'll have the chance to diversify your skills and enjoy significant opportunities for financial and professional advancement.What makes us unique? We are targeting some of the most pressing challenges in biology today, assembling an exceptional team of engineers, scientists, and problem solvers dedicated to innovating the next generation of technologies that will decode the complexities of biological systems.Embrace this exceptional opportunity to contribute to a promising start-up while collaborating with talented, down-to-earth individuals.Reporting to the Head of Operations & Corporate/Business Development, the Director of Corporate & Business Development will spearhead our strategic initiatives and partnership efforts within the Cell & Gene Therapy and Drug Discovery sectors. This pivotal role will influence how Cellanome's technologies and products are marketed and sold to BioPharma clients, including CDMOs. The ideal candidate will blend in-depth technical knowledge with a proven track record in business development to identify, evaluate, and finalize strategic deals that propel our growth. Key responsibilities include:Sourcing, evaluating, and negotiating development deals, licensing agreements, and strategic partnerships with pharmaceutical, biotech, and CDMO firms in the Cell & Gene Therapy and Drug Discovery sectors.Building and managing consortiums to promote collaborative research initiatives and multi-partner programs utilizing Cellanome's technology.Collaborating with internal teams to refine product offerings that leverage Cellanome's technology platform to meet evolving market demands.Establishing and maintaining a strong pipeline of qualified opportunities and driving deals to successful closure.Gathering market intelligence and competitive insights to guide product strategy and positioning.Representing Cellanome at industry conferences and client meetings.

Job Title: Creative Art DirectorDepartment: CreativeReports To: Associate Creative Director, ArtPosition Summary:As a Creative Art Director at Fishawack Communications, you will play a pivotal role in the conception and design of integrated advertising campaigns. Your leadership will guide the creative process, ensuring that all work aligns with strategic objectives while being completed punctually and within budget constraints.Your responsibilities will include developing innovative designs, layouts, and concepts that enhance brand visibility across all agency projects. Collaborating closely with a copy partner, you will generate unique ideas and concepts in response to creative briefs. This role requires a passion for selling ideas to peers and clients, alongside supporting senior creative staff and collaborating with teammates.At Fishawack, our ambition is to elevate our clients' businesses and brands through exceptional ideas. We believe that creativity can spark from anywhere, and we value a culture defined by curiosity, collaboration, integrity, and resourcefulness.Key Creative Department Attitudes:Curiosity: Be open-minded to ideas from all sources; adaptable individuals often embrace change.Collaboration: Exhibit self-confidence without arrogance; work effectively with diverse teams.Integrity: Uphold honesty and respect in all interactions.Resourcefulness: Find innovative solutions to meet the needs of clients and colleagues.Basic Responsibilities:Independently conceptualize, develop, and design content aligned with strategic direction.Collaborate with senior art staff and copywriters on concepts and layouts for client, in-house, and new business initiatives.Enhance your conceptual abilities in partnership with senior art team members.Prepare detailed layouts and storyboards.Ensure timely completion of assignments.Coordinate with in-house art departments and external suppliers for project fulfillment.

At Art of Problem Solving, we are revolutionizing the educational journey for families and students, transforming the fragmented experiences of discovery and long-term learning into a seamless, unified adventure. As the Director of Product Design, you will spearhead this transformation, enhancing both the customer journey and the learning experience. You will influence how families discover and choose AoPS, as well as how students interact with and progress through our comprehensive curriculum. Additionally, you will play a crucial role in integrating our dynamic brand identity into our products, ensuring it resonates not just visually, but is fundamentally woven into the functionality and feel of our learning tools. This leadership position is designed for an experienced player-coach who can define strategic directions, elevate design standards, and actively participate in team design efforts through constructive critique, mentorship, design workshops, and the exploration of innovative tools and technologies that enhance our building processes. Key Responsibilities: Establish and drive a cohesive design vision across discovery, enrollment, and learning, harmonizing fragmented products and journeys into an integrated system. Translate AoPS's evolving brand identity into engaging product experiences, ensuring our products effectively support the learning process. Cultivate collaboration between Product, Design, and Engineering teams by enhancing workflows and adopting contemporary tools (including AI) to boost efficiency, quality, and teamwork. Collaborate closely with academic teams to ensure pedagogical insights significantly inform the design of learning experiences. Develop and implement design systems, standards, and practices to promote consistency, quality, and productivity across teams. Lead and nurture a robust design team by recruiting, mentoring, and developing designers, fostering a culture of thoughtful critique and high standards.

Access Your Potential.Join us in crafting dynamic and unforgettable experiences that ignite inspiration, foster connections, and unleash creativity—while enjoying the process.We’re on the lookout for a Director of Events in San Diego, CA!Become a pivotal part of our mission to design and execute memorable experiences that motivate individuals and lead a top-tier Events team throughout the West territory. At Access, you will engage in collaboration, innovation, and operational excellence while nurturing a culture rooted in creativity, accountability, and outstanding client service.This impactful leadership position is tasked with directing a team of event experts who orchestrate intricate corporate meetings, incentive programs, and large-scale events across the region.Position OverviewAs the Director of Events (DOE), you will define the strategic vision and oversee the comprehensive management of the Events team, ensuring operational excellence across all initiatives within the West territory.You will guide a team dedicated to delivering sophisticated corporate meetings, incentive programs, and large-scale events, guaranteeing that all projects adhere to Access's standards for quality, profitability, and client satisfaction.Your responsibilities will include managing team dynamics, performance metrics, and project assignments while ensuring exceptional client delivery, robust financial results, and seamless interdepartmental collaboration. The DOE will work closely with Sales, Creative, and executive leadership to drive innovation, support territorial expansion, and foster a strong, solution-oriented team environment.This role is crucial in guaranteeing that programs are executed to the highest standards while achieving revenue, profitability, and client satisfaction targets.Key ResponsibilitiesTeam Leadership & DevelopmentProvide leadership and mentorship to Senior Managers, Event Managers, and Event Associates, encouraging professional growth and long-term engagement.Promote a culture of creative excellence, accountability, and continuous learning through coaching and regular team alignment.Collaborate with Talent Operations and executive leadership to recruit, onboard, and nurture a diverse pipeline of future leaders.Utilize KPIs and analytics to enhance team performance and program outcomes.

Join Acadia Pharmaceuticals as the Director of Manufacturing, where you will lead our manufacturing initiatives in both Princeton, NJ and San Diego, CA. This pivotal role involves overseeing production processes, ensuring compliance with industry standards, and managing teams to achieve operational excellence.

Join the 9amHealth TeamAt 9amHealth, we are pioneering a new standard of care in cardiometabolic health. Our innovative, comprehensive approach addresses obesity, diabetes, hypertension, and cholesterol management through personalized care plans, medication prescriptions, and expert guidance. Our mission is to empower our members to achieve healthier lifestyles every day.Founded in San Diego, California, we are backed by prominent investors, including 7Wire Ventures, Human Capital, Founders Fund, Define Ventures, Speedinvest, iSeed Ventures, and StartUp Health, with a total funding of $25 million. Our team, comprised of experts from the successful diabetes management app mySugr, acquired by Roche in 2017, is dedicated to transforming the landscape of cardiometabolic health.Role OverviewThe Enterprise Account Executive at 9amHealth is a pivotal role focused on driving new business opportunities by offering digital health solutions to leading employer clients. This strategic position involves securing commercial sales, fostering partnerships with health plans and pharmacy benefit managers (PBMs), and developing scalable strategies for employer adoption. Reporting to the Chief Commercial Officer, you will play a crucial role in expanding 9amHealth's footprint in the employer benefits sector and enhancing access to our innovative care solutions.This position is primarily focused on the Western regions of the U.S., making it ideal for candidates based in the Pacific Time Zone.

Genesis Molecular AI is on a mission to transform drug discovery through innovative computational chemistry solutions. We are building a premier team of experts in computational chemistry, and we invite you to join us as a Senior CADD Scientist. In this pivotal role, you will collaborate closely with our cutting-edge wet lab scientists and work alongside our distributed computational chemistry and CADD science teams throughout the United States.Key Responsibilities:Employ a blend of industry-standard and proprietary AI-driven CADD tools to steer small molecule drug discovery initiatives across a varied target landscape, including innovative targets with limited chemical precedents.Implement methodologies such as virtual screening, molecular simulation, and potency and ADMET prediction to facilitate critical decision-making processes in drug discovery.Work collaboratively with medicinal chemists to design molecules and develop tailored computational strategies for specific projects.Serve as a bridge among teams, effectively communicating between our computational chemistry and medicinal chemistry groups to promote seamless information exchange and collaborative decision-making.Thrive in a dynamic environment that encourages innovation and rapid iteration.

At Genesis Molecular AI, we are assembling a premier computational chemistry team dedicated to transforming drug discovery through state-of-the-art machine learning and biophysical simulations. We invite applications for the role of Principal CADD Scientist, who will collaborate closely with our scientists in the advanced wet lab and our distributed computational chemistry and CADD teams located across the United States.Key ResponsibilitiesEmploy a mix of industry-leading and proprietary AI-driven CADD tools to steer small molecule drug discovery projects across a wide array of targets, including innovative targets with limited chemical precedents.Implement methodologies such as virtual screening, molecular simulation, and ADMET prediction to facilitate critical decision-making during the drug discovery process.Work in tandem with medicinal chemists in molecular design and the formulation of project-specific computational strategies.Serve as an effective liaison among the computational and medicinal chemistry teams, ensuring smooth communication and collaborative decision-making.Thrive in a fast-paced environment that champions innovation and rapid iteration.QualificationsPh.D. in Computational Chemistry, Structural Biology, or a closely related discipline. Candidates with a Ph.D. in organic or medicinal chemistry and substantial laboratory experience transitioning to industry roles in CADD may also be considered.Comprehensive understanding of structure-based drug design and protein-ligand interactions.Expertise in industry-standard CADD software such as MOE, PyMOL, and Schrödinger Suite.A minimum of 5 years of experience as a CADD scientist in the pharmaceutical or biotechnology sector, with direct involvement in active drug discovery projects.While onsite collaboration in our San Diego lab is preferred, we are open to accommodating remote team members.What We OfferCompetitive salary and benefitsComprehensive health care plans, including medical, dental, and vision insurance fully covered for employeesEligibility for stock options

Join our team as a Design Director, where you will lead innovative design projects and inspire creativity within our talented team.PLEASE NOTE: This position is part of Lever's testing environment and is not open for applications.At Lever, we are revolutionizing the hiring process. Established a decade ago, we help organizations like Netflix, Yelp, Cirque du Soleil, Shopify, and Spotify attract and hire exceptional talent. Our cutting-edge hiring software is trusted by top companies, and we pride ourselves on being recognized as the #1 workplace in San Francisco and among the best in the United States. We value our team members, or 'Leveroos', and are committed to fostering a people-first culture as we continue to grow.

Join Our Team as the Director of Pricing! Berkshire Hathaway Homestate Companies is actively seeking a strategic and analytical Director of Pricing to enhance our Actuarial team. This pivotal role involves leveraging industry insights and company performance metrics to craft and execute comprehensive pricing strategies tailored to our Workers Compensation sector across different regions and markets. Moreover, you will play a crucial role in providing technical support for optimizing our pricing models and analytical tools. In this position, you will foster collaborative relationships with both internal teams and external clients, including data analytics, actuaries, underwriting, and marketing departments. Your ability to distill complex data into actionable insights will be essential for guiding sound decision-making within the organization. Presenting your findings clearly and effectively to business stakeholders, while articulating underlying assumptions and validations, will be a key aspect of your success.

Join Samsara as a Commercial Account Executive, where you will play a pivotal role in driving our sales efforts and establishing strong relationships with clients. You will be responsible for identifying new business opportunities, nurturing client relationships, and ultimately driving revenue growth in a fast-paced environment.In this role, you will leverage your expertise to understand client needs, present tailored solutions, and ensure client satisfaction. Your ability to communicate effectively and build rapport will be key to your success.