Analytical Scientist

Join our dynamic team as an Analytical Scientist where you will play a pivotal role in driving scientific innovations. In this contract position, you will leverage your analytical expertise to conduct experiments, analyze data, and contribute to cutting-edge projects that impact our future.

Lead the analytical development and product characterization activities for our diverse drug development portfolios independently. Oversee, provide technical guidance, and direct analytical method development, transfer, validation, release, and stability testing activities at contract development and manufacturing organizations (CDMOs). Serve as a subject matter expert for comprehensive physical and chemical characterization of new chemical entities (NCEs) at contract research organizations (CROs).Independently design, conceptualize, and execute experiments while interpreting and presenting data and conclusions to a variety of audiences, including senior leadership. Tackle complex problems utilizing traditional and innovative analytical techniques. Ensure accurate and timely lab records in compliance with good documentation practices and all applicable laboratory, safety, quality, and regulatory standards.Develop and implement strategic project plans for internal and external projects, ensuring that product requirements are accurately designed and delivered on schedule for all stakeholders throughout the drug development continuum—from discovery through preclinical, clinical, and commercial stages. Provide technical support during investigations at CDMOs and CROs in collaboration with quality teams.Author and review technical reports, data packages, and relevant sections for health authority submissions including INDs, NDAs, and annual reports, while supporting due diligence and partnership efforts.Exhibit excellent communication skills in project management, including budget planning, overseeing progress and periodic accruals, and coordinating contracts, purchase orders, and invoices with finance; ensure follow-ups and maintain project timelines to meet high-quality deliverables.

Join Alumis Inc., a pioneering precision medicines company dedicated to transforming the lives of patients suffering from autoimmune diseases. Despite significant advancements in treatment over the past two decades, many individuals with immunologic conditions still struggle; our mission is to fundamentally improve their outcomes.The CMC team at Alumis is on the lookout for a driven and highly skilled Senior Scientist I in Analytical Development. In this role, you will contribute significantly to our research efforts, utilizing your expertise to develop and validate analytical methods, ensuring the quality and efficacy of our innovative therapeutics.

About Us: Calico Life Sciences LLC, a cutting-edge research and development firm founded by Alphabet, is dedicated to unraveling the complexities of human aging through advanced technologies and innovative model systems. Our mission is to leverage this understanding to create interventions that promote longer, healthier lives. With state-of-the-art technology labs, a culture of curiosity-driven discovery, and a robust pipeline of drug development in collaboration with both academic and industry partners, Calico is an inspiring environment for catalyzing medical breakthroughs. Job Overview: We are on the lookout for a dynamic and passionate Scientist/Senior Scientist in Aging Biology to become a pivotal member of our Translational Medicine team. In this vital role, you will investigate the mechanisms of action (MOA) of therapeutic targets within our aging biology pipeline. The successful candidate will define the molecular and cellular pathways integral to our research programs, translating novel in vivo findings into a profound mechanistic understanding that will guide clinical development. The ideal candidate will possess substantial expertise in cell biology, MOA studies, and complex signaling pathways. Key Responsibilities: Design and implement experimental strategies to elucidate the molecular and cellular mechanisms of action for aging-related targets and biomarkers, providing insights that steer program direction. Execute in vitro and ex vivo studies to explore target biology in significant aging-related processes, such as stem cell function, tissue repair, and signaling or transcriptional regulation. Analyze acute and chronic pathway modulation in tissue injury and aging models to comprehend the evolution of stress responses and repair mechanisms in aging. Investigate the molecular drivers of in vivo phenotypes in preclinical aging models to identify biomarkers and translatable mechanisms for clinical development. Collaborate with in vivo pharmacology and biomarker teams to select optimal preclinical models that effectively probe target biology. Engage with cross-functional teams (e.g., Biomarkers, Genomics, Protein Sciences) to integrate multi-omic datasets and construct a comprehensive mechanistic framework. Analyze, interpret, and present complex data along with strategic recommendations to internal project teams and senior leadership. Maintain rigorous experimental documentation and contribute to internal reports, publications, and regulatory submissions.

Join AbbVie as a Senior Scientist I in our Quality Control team focused on Biologics Analytical Research & Development. In this pivotal role, you will leverage your expertise in analytical methods to ensure the quality and compliance of our biologic products. Collaborate with cross-functional teams to drive innovative solutions and contribute to the advancement of our research initiatives.

Join our dynamic team at Mindlance as an Associate Scientist. In this pivotal role, you will contribute to groundbreaking research initiatives and assist in the development of innovative solutions within the scientific community. Your expertise and analytical skills will help drive forward our mission to advance scientific knowledge and technology.

Join Artech Information Systems LLC as a Visual Analytics Associate in South San Francisco. In this role, you will leverage your analytical skills to transform complex data into visually engaging reports and dashboards. Collaborate with cross-functional teams to drive insights and enhance decision-making processes.

Overview:We are in search of a proactive and results-driven individual who takes personal ownership of their work and thrives in a fast-paced environment. Join our innovative team dedicated to the development and characterization of clinical-scale manufacturing processes for Chimeric Antigen Receptor T cell (CART) therapies. The ideal candidate will play a key role in developing and qualifying analytical methods essential for the characterization, release, and stability testing of CART products.Responsibilities:- Provide analytical support for clinical-scale non-GMP/GMP IND-enabling manufacturing operations, focusing on the qualification of in-process and release methods, as well as technology transfer internally and externally to support the manufacturing and release of clinical materials.- Contribute significantly to the successful development and execution of advanced analytical methods for the characterization of CART manufacturing processes and products.- Collaborate effectively with team members and stakeholders to understand process/product relationships, enhance product characterization, and identify critical cellular quality attributes.- Demonstrate accountability, strong interpersonal skills, and effective communication with leadership and peers to foster productive interactions and contribute to project technical teams.- Utilize exceptional organizational skills and scientific expertise to establish high-quality laboratory practices, ensuring consistent and accurate test data.- Maintain timely documentation in electronic laboratory notebooks and author or contribute to technical reports related to regulatory filings as necessary.- Regularly present data and strategies to scientists and management in both internal and external venues, as well as publish findings in peer-reviewed journals when appropriate.

About Us:Calico Life Sciences LLC, founded by Alphabet, is a pioneering research and development entity dedicated to advancing our understanding of human aging through cutting-edge technologies and model systems. Our mission is to leverage this knowledge to develop interventions that promote longer, healthier lives. At Calico, we foster a culture of curiosity-driven science, supported by a robust drug-development pipeline in collaboration with leading academic and industry partners, making us a dynamic environment for medical innovation.Position Overview:We are on the lookout for a seasoned Scientist to join our mass spectrometry proteomics team. The ideal candidate will exhibit enthusiasm, attention to detail, and exceptional organizational skills while tackling complex scientific challenges. This role focuses on employing chemoproteomics techniques via mass spectrometry to facilitate drug discovery, involving extensive sample handling and optimization of proteomics methodologies to propel our drug discovery initiatives forward.

About Us: Calico Life Sciences LLC, founded by Alphabet, is a pioneering research and development entity dedicated to advancing our understanding of the biological mechanisms of human aging. Our mission is to leverage cutting-edge technologies and innovative model systems to create interventions that promote longer, healthier lives. With our state-of-the-art laboratories, commitment to curiosity-driven discovery, collaborative partnerships across academia and industry, and a dynamic drug development pipeline, Calico is an inspiring environment for driving impactful medical breakthroughs. Position Overview: The Cellular Models and Assay Technologies (CMAT) laboratory and the Microscopy group at Calico are in search of a highly skilled and driven bench Scientist to join our innovative teams. This position is at the forefront of spatial biology, concentrating on the intricate mapping of molecular environments involving proteins and protein complexes within both live and fixed cells and tissues. The ideal candidate will spearhead the creation and application of Laser Capture Microdissection (LCM) workflows integrated with various proximity biotinylation techniques to achieve exceptional resolution in multiomics experiments specific to cells and tissues. As a crucial member of our drug discovery and fundamental research initiatives, the successful applicant will play a significant role in identifying and validating novel therapeutic targets and biomarkers. This hands-on position necessitates a profound understanding of cell and tissue biology, biochemistry, microscopy, and image analysis, along with the capability to develop or adapt novel methodologies as required. We seek an independent, adaptable, and proactive scientist with outstanding communication skills who can effectively manage complex studies in a fast-paced environment.

Join our dynamic team at Artech Information Systems LLC as a Bench Scientist. This entry-level role offers an exciting opportunity to work in a laboratory environment, contributing to innovative scientific research and experiments.

About Xaira TherapeuticsXaira Therapeutics is a pioneering biotech startup dedicated to revolutionizing drug discovery and development through the power of artificial intelligence (AI). Our mission is to lead the advancement of generative AI models designed specifically for creating innovative protein and antibody therapeutics. This allows us to tackle previously challenging molecular targets and develop effective medicines. We are also at the forefront of developing foundational models for biology and disease, facilitating improved target identification and patient stratification. Through our cutting-edge technologies, we aim to consistently discover novel therapies and enhance the success rates of drug development. Xaira has its headquarters in the vibrant San Francisco Bay Area, Seattle, and London.Position OverviewWe are on the lookout for dynamic and passionate candidates to join our innovative team as an AI Scientist! In this role, you will leverage your experience in developing and implementing advanced deep learning methodologies, showcasing a proven record of AI innovation through publications in the fields of Artificial Intelligence or Machine Learning, or through significant interdisciplinary projects. As a vital member of our core AI team, composed of exceptionally talented and creative individuals, you will spearhead exciting projects aimed at advancing state-of-the-art AI models in biology that influence drug discovery and clinical development. This role also provides the opportunity to collaborate with interdisciplinary experts in world-class biology, drug discovery, and clinical domains. Xaira values diversity and encourages candidates from all backgrounds and experiences to apply, as we believe that teams thrive when varied perspectives are included.The position is available in the following locations: San Francisco Bay Area, Seattle, and London.

About Us: Calico Life Sciences LLC, founded by Alphabet, is a pioneering research and development firm with the mission to leverage cutting-edge technologies and experimental systems to deepen our understanding of the biology behind human aging. Our goal is to translate this knowledge into innovative interventions that enhance the quality and longevity of life. With a vibrant drug-development pipeline and a commitment to curiosity-driven scientific exploration, Calico offers a dynamic environment where medical breakthroughs are catalyzed and realized. Position Overview: We are on the lookout for a dedicated in vivo scientist to propel our neurodegenerative disease research forward, specifically targeting Parkinson's disease. This role is vital for designing, executing, and interpreting experiments utilizing rodent models to explore neurological and aging disorders while evaluating potential therapeutic interventions. The successful candidate will enhance our Translational Neuroscience team's capacity for in vivo research, establish sophisticated models for thorough investigation, and assess novel drug mechanisms of action. Additionally, the scientist will contribute to modeling innovative aspects of neurodegenerative diseases, integrate insights from human cohorts, and develop mechanistic models for hypothesis testing stemming from new target discoveries. Key Responsibilities: Develop and characterize novel in vivo models related to neurodegeneration and age-associated biology. Design and implement in vivo functional experiments for target validation and mechanistic biology studies. Conduct comprehensive animal behavioral assessments to delineate neurological phenotypes. Analyze, interpret, and effectively communicate data and results to the team. Maintain meticulous records of experiments, data, and findings in compliance with Calico guidelines. Participate in experimental design, data interpretation, and results presentation. Foster collaboration across multiple functional teams. Ensure adherence to all animal welfare regulations and institutional guidelines.

Join our dynamic team as a Scientist I and contribute to groundbreaking research that drives innovation in the field. You will be an integral part of our scientific community, focusing on developing solutions that enhance our understanding of complex biological systems.

Join Veracyte, a trailblazing organization dedicated to revolutionizing cancer care for patients worldwide. At Veracyte, our team members have the opportunity to make a significant difference in patients' lives while thriving in a mission-driven environment. We embrace the Veracyte way, which emphasizes collaboration, guided by our core values, to equip clinicians with the insights necessary for transformative patient care.Our Core Values:Innovative Mindset: We boldly pursue innovation, learn from challenges, and remain steadfast in our commitment to enhancing cancer care.Action-Oriented: We prioritize urgency, uphold quality standards, and infuse enjoyment into our dedicated efforts.Collaborative Spirit: We engage in open dialogue, strive for understanding, and celebrate our collective achievements.Deep Care: We honor our diversity, uphold ethical standards, and support each other.Position Overview:We are in search of an accomplished and passionate Bioinformatics Scientist to become a key member of our Bioinformatics and Data Science Team, focused on the creation of regulated diagnostic products. The ideal candidate will possess extensive knowledge of NGS technologies and a robust understanding of regulatory frameworks such as CAP/CLIA and IVD product development. This role is pivotal in the design, development, and optimization of our next generation of genomic assays. A unique combination of bioinformatics expertise, assay optimization experience, analytical validation skills, and a strong foundation in molecular biology is essential, along with a commitment to transforming complex biological data into actionable insights.

Join Veracyte as a Senior Computational Development Scientist, where you will play a pivotal role in our mission to transform patient care through innovative genomics. In this remote position, you will leverage cutting-edge computational techniques to analyze complex genomic data, contributing to groundbreaking discoveries in cancer diagnostics.

We are seeking a dedicated and detail-oriented Bench Scientist to join our innovative team located in South San Francisco. As a Bench Scientist, you will be responsible for conducting experiments, analyzing results, and contributing to our research projects. This is an excellent opportunity for individuals who are passionate about scientific discovery and wish to advance their careers in a dynamic environment.

About Xaira TherapeuticsXaira Therapeutics is a cutting-edge biotechnology startup that harnesses the power of artificial intelligence to revolutionize drug discovery and development. Our mission is to pioneer generative AI models that design innovative protein and antibody therapeutics, targeting previously challenging molecular entities. We are also creating foundational models to enhance biological and disease understanding, facilitating improved target identification and patient stratification. Our technologies aim to consistently identify breakthrough therapies and elevate success rates in drug development. Xaira is proudly headquartered in the San Francisco Bay Area, with additional locations in Seattle and London.About the RoleWe are seeking a passionate and detail-oriented protein biochemist who excels in hands-on laboratory execution. Your enthusiasm for display technology and drug discovery will drive you as you work towards developing transformative treatments for patients. You thrive in collaborative and fast-paced settings, continuously seeking to push the frontiers of scientific innovation.

We are seeking a dedicated and innovative CART Scientist to join our dynamic team in South San Francisco. As a vital member of our research team, you will contribute to cutting-edge advancements in CAR T-cell therapy, focusing on enhancing the efficacy and safety of treatments for various hematologic malignancies.

Join Integrated Resources Inc. as a Bench Scientist, where you will play a pivotal role in advancing our scientific research initiatives. In this position, you will be responsible for conducting experiments, analyzing data, and collaborating with cross-functional teams to develop innovative solutions. Your keen analytical skills and attention to detail will be crucial in ensuring the accuracy and integrity of our scientific findings.We are looking for a passionate individual with a strong background in laboratory techniques and a commitment to excellence. If you thrive in a fast-paced environment and are eager to contribute to groundbreaking research, we want to hear from you!