Senior Medical Science Liaison - Western Region

Join Oric Pharmaceuticals as a Senior Medical Science Liaison in the Western Region, where you will play a pivotal role in advancing our mission to innovate cancer therapies. As a key member of our Medical Affairs team, you will collaborate with healthcare professionals and stakeholders to communicate the scientific value of our products.

Join Oric Pharmaceuticals as a Senior Medical Science Liaison for the Eastern Region, where you will play a pivotal role in advancing our medical initiatives and fostering relationships with key opinion leaders. In this dynamic position, you will leverage your expertise to communicate scientific information and provide support to our clinical programs. Ideal candidates will have a robust background in medical affairs and a passion for making a difference in patient care.

Join Oric Pharmaceuticals as a Senior Medical Science Liaison in the Central Region, where you will play a pivotal role in advancing our mission to develop innovative medicines for patients. In this key position, you will engage with healthcare professionals, providing critical scientific information and fostering collaborative relationships that enhance our clinical and research initiatives.

About Us: Calico Life Sciences LLC, a pioneering research and development entity backed by Alphabet, is dedicated to advancing the understanding of human aging through innovative technologies and modeling systems. Our mission is to leverage this knowledge to develop interventions that enhance health span, enabling individuals to live longer, healthier lives. With a commitment to curiosity-driven scientific discovery and collaborative partnerships in drug development, Calico offers an inspiring environment to foster significant medical breakthroughs. Position Overview: As a Medical Director/Senior Medical Director at Calico, you will report directly to the Head of Clinical Sciences. Your primary focus will be on providing strategic insights into the translational and clinical development of projects aimed at enhancing human health span through a better understanding of aging and age-related diseases, with a specific emphasis on neurologic and neuropsychiatric conditions. Key Responsibilities: Lead cross-functional teams to translate preclinical mechanistic data to clinical applications and develop translational biomarkers for innovative targets in neurologic and neuropsychiatric fields. Collaborate with research and drug development leaders both within and outside Calico to refine disease indication strategies for new targets. Utilize clinical expertise to guide the creation and application of preclinical models in partnership with discovery and biomarker scientists. Work closely with various drug development teams to shape new clinical programs throughout their lifecycle, particularly focusing on translational and early clinical development phases (Phase 0 through Phase 2). Design and implement experimental medicine studies to validate the mechanism of action for novel targets in neuropsychiatric disorders. Formulate and execute early clinical development strategies to establish proof of concept across various neuropsychiatric indications. Contribute scientific and medical knowledge for protocols, Investigator Brochures, Clinical Study reports, regulatory submissions, and other vital documents.

Lead the analytical development and product characterization activities for our diverse drug development portfolios independently. Oversee, provide technical guidance, and direct analytical method development, transfer, validation, release, and stability testing activities at contract development and manufacturing organizations (CDMOs). Serve as a subject matter expert for comprehensive physical and chemical characterization of new chemical entities (NCEs) at contract research organizations (CROs).Independently design, conceptualize, and execute experiments while interpreting and presenting data and conclusions to a variety of audiences, including senior leadership. Tackle complex problems utilizing traditional and innovative analytical techniques. Ensure accurate and timely lab records in compliance with good documentation practices and all applicable laboratory, safety, quality, and regulatory standards.Develop and implement strategic project plans for internal and external projects, ensuring that product requirements are accurately designed and delivered on schedule for all stakeholders throughout the drug development continuum—from discovery through preclinical, clinical, and commercial stages. Provide technical support during investigations at CDMOs and CROs in collaboration with quality teams.Author and review technical reports, data packages, and relevant sections for health authority submissions including INDs, NDAs, and annual reports, while supporting due diligence and partnership efforts.Exhibit excellent communication skills in project management, including budget planning, overseeing progress and periodic accruals, and coordinating contracts, purchase orders, and invoices with finance; ensure follow-ups and maintain project timelines to meet high-quality deliverables.

About Us: Calico Life Sciences LLC, founded by Alphabet, is at the forefront of research and development, dedicated to unraveling the complexities of human aging through cutting-edge technologies and innovative model systems. Our mission is to leverage this understanding to create interventions that empower individuals to enjoy longer and healthier lives. With a dynamic drug-development pipeline, fueled by curiosity-driven discovery science and collaboration with academic and industry partners, Calico is a vibrant hub for catalyzing medical breakthroughs. Role Overview: We are looking for an experienced Associate Director of Medical Writing who will lead and oversee the creation and review of high-quality clinical and regulatory documents, ensuring compliance with relevant guidelines and regulations. The ideal candidate will excel in cross-functional collaboration, engaging effectively with various stakeholders while fostering a positive team dynamic. This role demands strong project management and technical leadership skills, accompanied by a focus on scientific excellence. Key Responsibilities: Document Leadership and Authoring: Lead medical writing efforts for clinical programs. Serve as a subject matter expert in medical writing, collaborating with the Clinical Science team to produce essential clinical documents such as study protocols, informed consent forms, clinical study reports, and regulatory submissions. Work closely with the regulatory team to ensure timely and high-quality completion of regulatory documents required for submissions, including health authority meeting requests and briefing packages. Vendor Management: Guide external writers in prioritizing tasks, developing content, and managing timelines to support clinical and regulatory activities. Process Improvement: Establish best practices for medical writing, including standard timelines and templates. Collaborate with the Quality Assurance team to create and update Standard Operating Procedures for medical writing processes to ensure compliance with ICH requirements.

Alumis Inc. is at the forefront of precision medicine, dedicated to revolutionizing the lives of individuals suffering from autoimmune diseases. Despite advancements in treatment over the past two decades, many patients with immunological disorders continue to endure challenges—our mission is to fundamentally improve their outcomes.We are in search of a seasoned Senior Medical Director of Clinical Development to oversee a broad spectrum of rheumatology and autoimmune clinical drug development, ranging from discovery research to first-in-human, proof-of-concept, and Phase 3 studies. This pivotal role will lead multiple studies within our portfolio and collaborate closely with the cross-functional asset team to leverage comprehensive clinical expertise and successfully enhance clinical programs and overall asset strategies.Key Responsibilities:Act as the physician lead for LUMUS, a Phase 2b clinical trial with 388 patients aimed at assessing the efficacy, safety, and pharmacokinetics of ESK-001 in adults with moderately to severely active, autoantibody-positive systemic lupus erythematosus (SLE).Lead in-stream data reviews and reconciliation processes.Author critical clinical documents, including Protocol Amendments and Regulatory Submissions.Oversee the LUMUS medical monitor and engage in external scientific collaborations, including peer interactions with physicians.Represent Alumis broadly as a leader, driving corporate initiatives across the rheumatology domain.Inspire, manage, and coach team members to achieve their objectives through a focused and collaborative approach.Uphold the highest standards of integrity and scientific inquiry in drug development.Initial Goals:Establish trust and respect with key internal and external stakeholders, building a reputation as a strategic and productive partner.Deliver hands-on leadership, contributing expertise, and collaborating effectively with the operations team to ensure the success of LUMUS.Enhance and maintain the quality of study data, particularly regarding the main efficacy endpoints.

The RoleThe Clinical Development team at Maze Therapeutics is in search of a dynamic and experienced Senior Director of Safety Science. In this pivotal position, you will spearhead the establishment and scaling of safety science and pharmacovigilance (PV) practices within our organization. As the inaugural internal leader for Safety Science, you will be responsible for building the safety function from the ground up, while also providing strategic leadership across our diverse clinical portfolio.This highly visible and hands-on leadership role requires you to define and own the safety strategy for our clinical programs, which encompass both common and rare diseases in nephrology and cardiometabolic indications.Your end-to-end responsibilities will include safety surveillance, adverse event reporting, risk management, and PV governance. You will collaborate closely with teams in Clinical Development, Regulatory Affairs, Biostatistics, and Clinical Operations. As Maze progresses from early to late-stage program development, you will play a critical role in shaping our safety strategy.

At Alumis Inc., we are committed to revolutionizing the lives of individuals suffering from autoimmune diseases through precision medicine. Despite significant advancements in treatments over the past twenty years, many patients with immunologic conditions still face challenges. Our mission is to fundamentally improve patient outcomes.We are currently on the lookout for a seasoned Director of Thought Leader Liaison (TLL) with extensive expertise in Dermatology. This pivotal, field-based leadership role will be instrumental in guiding a team of TLLs to develop and implement Key Opinion Leader (KOL) engagement strategies for the U.S. launch of envudeucitinib, targeting Psoriasis.The chosen candidate will play a crucial role within our brand marketing team, collaborating with various stakeholders at the intersection of marketing, medical affairs, and field execution. This position carries accountability for team leadership, KOL strategy and execution, as well as generating strategic insights to inform brand strategy. A comprehensive understanding of medical science, outstanding leadership skills, and the ability to foster cross-functional team success are essential for this role.

Kardigan is dedicated to transforming heart health by developing treatments aimed at preventing and curing cardiovascular disease. The company’s mission is to end cardiovascular disease as the world’s leading cause of death. Multiple targeted therapies are in development, with a focus on delivering effective solutions for people affected by cardiovascular conditions. Kardigan’s leadership includes Tassos Gianakakos, Jay Edelberg, M.D., Ph.D., and Bob McDowell, Ph.D. This team previously led MyoKardia, where their work resulted in the discovery of mavacamten, the first cardiac myosin inhibitor, and culminated in MyoKardia’s acquisition by Bristol Myers Squibb in 2020. With a modern research platform and a strong pipeline of late-stage candidates, Kardigan is positioned to improve outcomes for patients living with heart disease. Values Patient-centric: Every decision prioritizes patients and their families. Authenticity: The culture encourages acceptance and values each individual. Curiosity: Ongoing learning and openness to new perspectives are encouraged. Team success: Collaboration, urgency, and shared achievement are essential for results. Enable the impossible: Innovation and thoughtful risk-taking drive scientific advancement. These values shape daily work and support Kardigan’s efforts to make a lasting difference in heart health.

At Alumis Inc., we are dedicated to revolutionizing the lives of patients afflicted with autoimmune diseases through precision medicine. Despite advancements in treatment over the last 20 years, a significant number of individuals with immunologic conditions continue to endure hardships; our mission is to fundamentally alter these patients' outcomes.We are in search of a highly skilled Senior Clinical Development Medical Director to lead various aspects of our dermatology and autoimmune clinical drug development initiatives, encompassing discovery research, first-in-human trials, proof of concept, and Phase 3 studies. This role will include overseeing one or more studies within our portfolio and collaborating with all cross-functional team members to leverage comprehensive clinical knowledge in successfully advancing clinical programs and the overall asset strategy.

We are seeking a dedicated and skilled Medical Technologist to join our team in South San Francisco. In this role, you will play a vital part in the healthcare process, utilizing your expertise to perform laboratory tests and analyses that aid in patient diagnosis and treatment.The ideal candidate will have a strong attention to detail, excellent problem-solving skills, and the ability to work effectively in a fast-paced environment. If you are passionate about making a difference in healthcare, we would love to hear from you.

Join AbbVie as a Scientific Director / Medical Director in the field of Medical Affairs focusing on Oncology, specifically targeting Ovarian Solid Tumor. In this pivotal role, you will lead strategic initiatives and research efforts aimed at improving patient outcomes through innovative therapies. Collaborate with cross-functional teams to develop and implement comprehensive medical strategies that align with our commitment to advancing oncology care.

Alumis Inc. is a pioneering company in precision medicine, committed to transforming the lives of patients grappling with autoimmune diseases. Despite significant treatment advancements over the past two decades, countless individuals with immunologic conditions continue to endure hardships. Our mission is to fundamentally enhance the outcomes for these patients.We have recently finalized our pivotal trials for envudeucitinib, a next-generation TYK2 inhibitor targeting moderate to severe plaque psoriasis, and we anticipate results from a potentially pivotal Phase 2b trial in systemic lupus erythematosus (SLE) by the third quarter of 2026.As an integral member of the Alumis team, you will spearhead the Medical Affairs function, overseeing Medical Affairs, Field Medical Liaisons, and publication initiatives. This role requires close collaboration with clinicians conducting Alumis’ clinical studies and our commercial team. We seek a proactive leader capable of devising strategies and driving cross-functional collaboration. This Vice President of Medical Affairs will report directly to the Chief Medical Officer.

About Us: Calico Life Sciences LLC, founded by Alphabet, is a pioneering research and development organization dedicated to leveraging cutting-edge technologies and innovative model systems. Our goal is to deepen our understanding of the biological processes governing human aging. By harnessing this knowledge, we aim to create interventions that empower individuals to enjoy longer, healthier lives. With our state-of-the-art technology labs and a dedicated commitment to curiosity-driven scientific exploration, alongside vibrant collaborations with academic and industry partners, we are at the forefront of groundbreaking medical advancements. Position Overview: The Associate Director of Clinical Science will play a crucial role in the strategic planning and implementation of translational and clinical development protocols across multiple therapeutic areas, aligning with Calico's mission to enhance human healthspan by exploring aging and age-related conditions. The ideal candidate will lead the development of innovative clinical strategies for designated programs, fostering a positive and collaborative team atmosphere. Key Responsibilities: Collaborate with the Head of Clinical Science and Medical Directors to lead or represent the Clinical Science function in cross-functional teams focused on executing clinical development plans that translate preclinical data into human studies targeting novel aging-related therapies. Draft and refine clinical sections of protocols from Phase 0 to Phase 2, working closely with interdisciplinary teams including Research, Biomarkers, Clinical Operations, Regulatory Affairs, Clinical Pharmacology, Biometrics, Pharmacovigilance, Toxicology, and Medical Writing. Contribute to the design and execution of experimental medicine studies aimed at demonstrating proof-of-mechanism for innovative targets in aging and related diseases. Engage with academic investigators to support the execution of Investigator-initiated trials. Review and contribute to critical study documents, such as Investigational Brochures, Clinical Study Reports, Statistical Analysis Plans, and IND/CTAs. Provide training to CROs and study site personnel on assigned protocols, addressing queries as they arise. Participate in the assessment and selection of CROs and study vendors.

Join Spirair Inc., a pioneering company dedicated to advancing medical technologies, as a Senior R&D Engineer. In this role, you will leverage your expertise to drive the development of innovative medical devices, collaborating with a multidisciplinary team to ensure compliance with regulatory standards and enhance patient outcomes.

Vilya is at the forefront of computational biotechnology, developing an innovative class of medicines designed to precisely target disease biology. We are committed to integrating computational strategies as a core aspect of drug discovery and development. Our advanced platform is founded on pioneering research and explores uncharted chemical spaces to create new molecular structures that do not exist in nature.We are leveraging our platform's capabilities to tackle previously unattainable targets across a wide range of medical indications. Vilya’s ultimate ambition is to address some of the most significant unmet medical needs of our time.Our Vision: To revolutionize technology and biology for the enhancement of human health.Our Mission: To establish an independent, leading biotech company grounded in intelligent drug design, aiming to cure the incurable.We are looking for a driven and enthusiastic Summer Intern to join our Structural Biology and Biology teams in South San Francisco for a 12-week internship in the summer of 2026. Reporting to the Director of Structural Biology, this in-office position will be vital in advancing our platform technology and facilitating the transition of orally available macrocycles into clinical settings.

At Alumis Inc., we are dedicated to revolutionizing the treatment of autoimmune diseases through precision medicine. Despite advancements in treatment over the past two decades, many patients with immunologic conditions still experience significant challenges. Our mission is to fundamentally improve outcomes for these patients.Position SummaryWe are actively seeking a highly qualified Senior or Executive Medical Director to spearhead the clinical development strategy for Phase 1 and Phase 2 trials assessing envudeucitinib and A-005, targeting new indications for the expansion of our innovative pipeline. This pivotal role will not only shape our clinical development portfolio from indication selection to proof-of-concept studies but will also establish you as a vital scientific leader collaborating with internal teams, regulatory bodies, and the broader medical community.

About Us: Calico Life Sciences LLC, a cutting-edge research and development firm founded by Alphabet, is dedicated to unraveling the complexities of human aging through advanced technologies and innovative model systems. Our mission is to leverage this understanding to create interventions that promote longer, healthier lives. With state-of-the-art technology labs, a culture of curiosity-driven discovery, and a robust pipeline of drug development in collaboration with both academic and industry partners, Calico is an inspiring environment for catalyzing medical breakthroughs. Job Overview: We are on the lookout for a dynamic and passionate Scientist/Senior Scientist in Aging Biology to become a pivotal member of our Translational Medicine team. In this vital role, you will investigate the mechanisms of action (MOA) of therapeutic targets within our aging biology pipeline. The successful candidate will define the molecular and cellular pathways integral to our research programs, translating novel in vivo findings into a profound mechanistic understanding that will guide clinical development. The ideal candidate will possess substantial expertise in cell biology, MOA studies, and complex signaling pathways. Key Responsibilities: Design and implement experimental strategies to elucidate the molecular and cellular mechanisms of action for aging-related targets and biomarkers, providing insights that steer program direction. Execute in vitro and ex vivo studies to explore target biology in significant aging-related processes, such as stem cell function, tissue repair, and signaling or transcriptional regulation. Analyze acute and chronic pathway modulation in tissue injury and aging models to comprehend the evolution of stress responses and repair mechanisms in aging. Investigate the molecular drivers of in vivo phenotypes in preclinical aging models to identify biomarkers and translatable mechanisms for clinical development. Collaborate with in vivo pharmacology and biomarker teams to select optimal preclinical models that effectively probe target biology. Engage with cross-functional teams (e.g., Biomarkers, Genomics, Protein Sciences) to integrate multi-omic datasets and construct a comprehensive mechanistic framework. Analyze, interpret, and present complex data along with strategic recommendations to internal project teams and senior leadership. Maintain rigorous experimental documentation and contribute to internal reports, publications, and regulatory submissions.

At Spirair, Inc., a dynamic medical device firm backed by venture capital, we are driven by innovation and a commitment to enhancing patient care and accessibility. Co-founded by two distinguished Stanford Biodesign and Innovation fellows, our mission is to revolutionize the treatment landscape with minimally invasive solutions that significantly improve patient outcomes. Our team collaborates with leading ENT specialists and industry experts to develop cutting-edge technologies that reshape healthcare experiences.We are seeking a proactive and creative Marketing Communications (Marcom) Manager who will partner closely with our Vice President of Marketing. This role involves strategizing and implementing customer and patient-centric marketing initiatives that align with Spirair's commercial goals. The ideal candidate will manage a diverse range of marketing communication activities, including the creation of engaging marketing materials, multimedia content, and social media strategies. If you thrive in a fast-paced startup culture and enjoy cross-functional collaboration, we want to hear from you!Main ResponsibilitiesCollaborate with marketing and sales leaders to design and refine compelling marketing strategies and messaging, proactively contributing innovative ideas.Ensure brand integrity and consistency across all marketing channels and materials.Oversee the production of marketing and sales collateral, including brochures, presentations, animations, and digital content.Manage relationships with external vendors and design agencies to efficiently meet corporate and sales needs.Coordinate logistics for sales training, customer events, and conferences, ensuring smooth execution and support.Enhance and maintain the corporate website by developing and updating content in collaboration with our web agency.Curate content and manage the company’s LinkedIn and other social media platforms, including post scheduling and internal approvals.Support the sales team in their marketing efforts and engage with healthcare professionals and patients regarding promotional initiatives.Perform additional tasks as required.