Senior Scientist, Process Development (I, II, III)

Position SummaryCellares is on the lookout for a dynamic and driven Senior Scientist with a strong background in cell therapy manufacturing to become a vital member of our Process Development team. This role offers a unique opportunity to collaborate with various departments and make substantial contributions to the advancement of our innovative cell therapy…

Join Veracyte, Inc., a leading biotechnology company dedicated to advancing diagnostic solutions for patients worldwide. We are seeking a talented Scientist III to contribute to our Diagnostic Product Development team on a contract basis. In this role, you will leverage your expertise in assay development and validation to drive innovative solutions that enhance patient care.

About Xaira TherapeuticsXaira Therapeutics is a pioneering biotech startup dedicated to harnessing the power of artificial intelligence to revolutionize drug discovery and development. Our company is at the forefront of creating generative AI models that design innovative protein and antibody therapeutics, aiming to produce medicines that target historically challenging molecular entities. We are also advancing foundational models for biology and disease, which facilitate better target identification and patient stratification. Our technologies collectively strive to continually unveil novel therapies and enhance success rates in drug development. Headquartered in the vibrant San Francisco Bay Area, with additional offices in Seattle and London, Xaira is shaping the future of medicine.About the RoleWe are on the lookout for a passionate Scientist with robust hands-on molecular biology expertise and a creative, analytical, and innovative approach. This position emphasizes aiding in the design, construction, and refinement of cutting-edge screening platforms and experimental workflows that drive biological discoveries at scale.The ideal candidate is a proactive individual who thrives in uncertain problem spaces, meticulously considers experimental design, and takes initiative in transforming initial concepts into dependable, reproducible systems. You will engage collaboratively with various teams, including automation, engineering, and computation, to invent new methodologies for generating high-quality biological data.

Join Veracyte, where we are dedicated to revolutionizing cancer care for patients globally. Our team offers a dynamic workplace where you can make a significant difference in patients' lives while growing your skills in a mission-driven environment. This embodies the Veracyte way—collaborating with shared values to provide clinicians with critical insights that lead to impactful patient decisions.Our Core Values:We Seek A Better Way: We innovate courageously, learn from challenges, and remain resilient in transforming cancer care.We Make It Happen: We act swiftly, uphold quality, and incorporate enjoyment into our hard work.We Are Stronger Together: We foster open collaboration, strive for understanding, and celebrate our successes.We Care Deeply: We appreciate our differences, uphold integrity, and support one another.The Position:We are seeking a driven individual to join our Assay Development group as a Scientist I. This laboratory-based role will focus on assay development for high-throughput operations, significantly contributing to Veracyte’s innovative diagnostic products. You will play a key role in study design and documentation, executing bench studies while adhering to rigorous design control requirements.

Join Alumis Inc., a pioneering precision medicines company dedicated to transforming the lives of patients suffering from autoimmune diseases. Despite significant advancements in treatment over the past two decades, many individuals with immunologic conditions still struggle; our mission is to fundamentally improve their outcomes.The CMC team at Alumis is on the lookout for a driven and highly skilled Senior Scientist I in Analytical Development. In this role, you will contribute significantly to our research efforts, utilizing your expertise to develop and validate analytical methods, ensuring the quality and efficacy of our innovative therapeutics.

Join our dynamic team as a Scientist I and contribute to groundbreaking research that drives innovation in the field. You will be an integral part of our scientific community, focusing on developing solutions that enhance our understanding of complex biological systems.

Join our dynamic team at LanceSoft, Inc. as an Assistant Scientist I/II in Preclinical Development. In this role, you will support innovative research initiatives that play a crucial role in the early stages of drug development. Your contributions will directly impact the quality of our preclinical studies, ensuring compliance with regulatory standards and enhancing our scientific results.

Join AbbVie as a Senior Scientist I in our Machine Learning team dedicated to advancing Biologics Drug Substance Development and Cell Culture Development. In this key role, you will leverage your expertise in machine learning to drive innovations that enhance our drug development processes.

About Us: Calico Life Sciences LLC, a pioneering research and development company founded by Alphabet, is dedicated to exploring advanced technologies and biological systems that enhance our understanding of human aging. Our mission is to utilize this knowledge to develop interventions that promote longer, healthier lives. With cutting-edge technology labs and a vibrant pipeline of drug development in collaboration with esteemed academic and industry partners, Calico stands as an inspiring environment for catalyzing medical breakthroughs. Position Overview: We are on the lookout for a seasoned Process Chemist to become a vital member of our laboratory-based chemical development team. The ideal candidate will possess extensive hands-on experience in process research, route scouting, and the scale-up of organic molecules. In this role, you will be responsible for designing, optimizing, and executing synthetic processes that facilitate the efficient, safe, and scalable manufacturing of small-molecule intermediates and active pharmaceutical ingredients (APIs). This position is laboratory-focused and requires strong experimental skills, a profound understanding of organic chemistry, and the ability to convert laboratory discoveries into reliable processes. Key Responsibilities: Develop, optimize, and troubleshoot synthetic routes for intermediates and drug substance candidates. Conduct laboratory experiments aimed at enhancing yields, selectivity, throughput, and impurity management. Perform detailed reaction analysis utilizing HPLC, GC, LC-MS, and other analytical methodologies. Execute impurity identification and synthesis. Identify and mitigate process risks concerning safety, scalability, and robustness. Collaborate with cross-functional teams, including analytical chemistry, formulations, and quality assurance. Prepare concise, data-driven reports and present experimental findings to project teams. Facilitate technology transfer to contract manufacturing organizations, including review of master batch records and process descriptions. Maintain precise laboratory documentation and comply with all safety and regulatory standards.

Join Veracyte, a pioneering company in genomic diagnostics, as a Scientist I for a 9-month contract. In this role, you will contribute to groundbreaking research and development initiatives aimed at enhancing diagnostic accuracy and patient care. Collaborate with a dynamic team of scientists and professionals while leveraging cutting-edge technologies in a fast-paced environment.

Join Artech Information Systems LLC as an Associate Scientist II in Product Assurance, where you will play a pivotal role in ensuring the quality and reliability of our innovative products. You will collaborate with a dynamic team to perform testing and validation, contributing to the development of cutting-edge technologies.

At Veracyte, we are thrilled to invite talented individuals to join our innovative team dedicated to revolutionizing cancer care for patients worldwide. Being part of Veracyte empowers our employees to make a profound impact on patient lives while fostering personal and professional growth in a mission-driven environment. This embodies the Veracyte way: a collaborative approach guided by our core values, enabling clinicians with insights to help patients make transformative decisions.Our Values:We Seek A Better Way: We boldly innovate, learn from setbacks, and remain resilient in our mission to transform cancer care.We Make It Happen: We act swiftly, uphold quality, and infuse enjoyment into our hard work.We Are Stronger Together: We foster open collaboration, strive for understanding, and celebrate our achievements.We Care Deeply: We embrace diversity, act ethically, and support one another. The Position:We are seeking an enthusiastic and driven individual to become a vital member of our Product Development team as a Senior Scientist. This role is focused on the development of assays for high-throughput operations, contributing to Veracyte's groundbreaking diagnostic products. You will play a key role in study design and documentation, executing bench studies while adhering to rigorous design control standards.

Join AbbVie as a Senior Scientist I in our Quality Control team focused on Biologics Analytical Research & Development. In this pivotal role, you will leverage your expertise in analytical methods to ensure the quality and compliance of our biologic products. Collaborate with cross-functional teams to drive innovative solutions and contribute to the advancement of our research initiatives.

insitro blends AI, large-scale biology, and drug discovery into a unified process. Predictive models guide laboratory experiments, while experimental results feed back to improve those models. This feedback loop aims to create a more efficient path from data to discovery. Role overview The Scientist I/II in Integrated Technology and Exploration designs and executes cell-based experiments, using both manual and automated workflows. The work focuses on generating key datasets that support and improve insitro’s predictive models. AI-generated predictions serve as hypotheses, which are tested at the bench. When results diverge from predictions, the scientist investigates whether the issue lies in the model, the experimental design, or the broader framework. Each experiment helps the system learn and become more accurate over time. What success looks like Consistent, high-quality execution of experiments that inform and refine predictive models Evidence-based contributions that improve the accuracy, calibration, and usefulness of the overall system Requirements Strong background in cell biology Comfort working at the intersection of experimental biology and computational modeling Curiosity and motivation to develop systems that improve through real-world data Work location and reporting This position is based onsite at insitro’s South San Francisco headquarters. Presence is required five days a week to maintain rapid feedback between experiments, automation, and AI analysis. The Scientist I/II reports to the Director of Integrated Technology Exploration.

AbbVie is seeking a dedicated Senior Scientist II specializing in Occupational and Environmental Toxicology to join our innovative team in South San Francisco. In this pivotal role, you will leverage your expertise to assess and mitigate the risks associated with chemical exposure in various environments, ensuring the safety and health of populations.

About Us: Calico Life Sciences LLC, a cutting-edge research and development firm founded by Alphabet, is dedicated to unraveling the complexities of human aging through advanced technologies and innovative model systems. Our mission is to leverage this understanding to create interventions that promote longer, healthier lives. With state-of-the-art technology labs, a culture of curiosity-driven discovery, and a robust pipeline of drug development in collaboration with both academic and industry partners, Calico is an inspiring environment for catalyzing medical breakthroughs. Job Overview: We are on the lookout for a dynamic and passionate Scientist/Senior Scientist in Aging Biology to become a pivotal member of our Translational Medicine team. In this vital role, you will investigate the mechanisms of action (MOA) of therapeutic targets within our aging biology pipeline. The successful candidate will define the molecular and cellular pathways integral to our research programs, translating novel in vivo findings into a profound mechanistic understanding that will guide clinical development. The ideal candidate will possess substantial expertise in cell biology, MOA studies, and complex signaling pathways. Key Responsibilities: Design and implement experimental strategies to elucidate the molecular and cellular mechanisms of action for aging-related targets and biomarkers, providing insights that steer program direction. Execute in vitro and ex vivo studies to explore target biology in significant aging-related processes, such as stem cell function, tissue repair, and signaling or transcriptional regulation. Analyze acute and chronic pathway modulation in tissue injury and aging models to comprehend the evolution of stress responses and repair mechanisms in aging. Investigate the molecular drivers of in vivo phenotypes in preclinical aging models to identify biomarkers and translatable mechanisms for clinical development. Collaborate with in vivo pharmacology and biomarker teams to select optimal preclinical models that effectively probe target biology. Engage with cross-functional teams (e.g., Biomarkers, Genomics, Protein Sciences) to integrate multi-omic datasets and construct a comprehensive mechanistic framework. Analyze, interpret, and present complex data along with strategic recommendations to internal project teams and senior leadership. Maintain rigorous experimental documentation and contribute to internal reports, publications, and regulatory submissions.

Lead the analytical development and product characterization activities for our diverse drug development portfolios independently. Oversee, provide technical guidance, and direct analytical method development, transfer, validation, release, and stability testing activities at contract development and manufacturing organizations (CDMOs). Serve as a subject matter expert for comprehensive physical and chemical characterization of new chemical entities (NCEs) at contract research organizations (CROs).Independently design, conceptualize, and execute experiments while interpreting and presenting data and conclusions to a variety of audiences, including senior leadership. Tackle complex problems utilizing traditional and innovative analytical techniques. Ensure accurate and timely lab records in compliance with good documentation practices and all applicable laboratory, safety, quality, and regulatory standards.Develop and implement strategic project plans for internal and external projects, ensuring that product requirements are accurately designed and delivered on schedule for all stakeholders throughout the drug development continuum—from discovery through preclinical, clinical, and commercial stages. Provide technical support during investigations at CDMOs and CROs in collaboration with quality teams.Author and review technical reports, data packages, and relevant sections for health authority submissions including INDs, NDAs, and annual reports, while supporting due diligence and partnership efforts.Exhibit excellent communication skills in project management, including budget planning, overseeing progress and periodic accruals, and coordinating contracts, purchase orders, and invoices with finance; ensure follow-ups and maintain project timelines to meet high-quality deliverables.

At Alumis Inc., we are dedicated to revolutionizing the treatment landscape for patients suffering from autoimmune diseases. Our mission is to make a significant impact on the lives of those who have not benefited from recent medical advancements. We invite you to join us on this crucial journey.We are in search of a highly skilled and driven Senior Scientist to join our Drug Product Development team. This role will thrive in a collaborative and dynamic setting, focusing on critical activities in the development of our innovative molecules. Your key responsibilities will include creating pre-formulation packages, selecting formulations, and developing manufacturing processes. Initially, this role will prioritize solid oral dosage form development, with potential for involvement in other dosage forms as we expand.

Cellares is on the lookout for a dedicated Senior Electrical Engineer who is enthusiastic about electrical design and automation. This key role will play a crucial part in advancing our cutting-edge cell therapy manufacturing platform.Your primary focus will be on the electrical systems integrated within cell therapy manufacturing equipment. This includes the design, documentation, and validation of control panels, PCBAs, and interconnecting cabling. You will collaborate with various departments to develop innovative products that make a significant impact in the cell and gene therapy sector. This position offers an exciting opportunity for career growth under the guidance of a highly skilled, cross-functional engineering team.We are seeking candidates who thrive in a dynamic, mission-oriented environment and are ready to embrace a wide range of challenges as our company expands.

About Us:Calico Life Sciences LLC, founded by Alphabet, is a pioneering research and development entity dedicated to advancing our understanding of human aging through cutting-edge technologies and model systems. Our mission is to leverage this knowledge to develop interventions that promote longer, healthier lives. At Calico, we foster a culture of curiosity-driven science, supported by a robust drug-development pipeline in collaboration with leading academic and industry partners, making us a dynamic environment for medical innovation.Position Overview:We are on the lookout for a seasoned Scientist to join our mass spectrometry proteomics team. The ideal candidate will exhibit enthusiasm, attention to detail, and exceptional organizational skills while tackling complex scientific challenges. This role focuses on employing chemoproteomics techniques via mass spectrometry to facilitate drug discovery, involving extensive sample handling and optimization of proteomics methodologies to propel our drug discovery initiatives forward.