About the job
Attention recruitment agencies: All agency inquiries are vetted through 4DMT’s internal Talent Acquisition team. No unsolicited resumes will be accepted. The 4DMT Talent Acquisition team must expressly engage agencies on any requisition. Agencies contacting hiring managers directly will not be tolerated, and doing so may impact your ability to work with 4DMT in the future.
4D Molecular Therapeutics (4DMT) stands at the forefront of late-stage biotechnology, pioneering durable and disease-targeted therapeutics aimed at revolutionizing treatment paradigms and delivering unparalleled benefits to patients. Our flagship product candidate, 4D-150, is engineered to serve as a foundational therapy for blinding retinal vascular diseases, offering multi-year sustained release of anti-VEGF (aflibercept and anti-VEGF-C) through a single, safe intravitreal injection. This innovative approach dramatically alleviates the treatment burden associated with current bolus injections. Currently, the lead indication for 4D-150 is wet age-related macular degeneration, which is advancing through Phase 3 development, while the second indication focuses on diabetic macular edema. We are also excited about our second product candidate, 4D-710, which represents the first successful genetic medicine for delivering and expressing the CFTR transgene in the lungs of cystic fibrosis patients via aerosol delivery.
GENERAL SUMMARY:
The Senior Manager of Data Management plays a pivotal role in overseeing the comprehensive clinical data management activities for assigned studies, providing operational oversight to both internal teams and external vendors. This position is integral to cross-functional study teams, contributing to the strategic planning, execution, and delivery of high-quality clinical trial data throughout all phases. The Senior Manager brings extensive knowledge of clinical data management processes, executing tasks independently while offering valuable guidance to other Data Managers and vendor partners.
Data management is a crucial function within the Clinical Development organization at 4DMT. Alongside Biostatistics and Statistical Programming within the Data Science group, we provide essential support for the company's clinical development programs focused on gene therapies for retinal diseases and other therapeutic areas.
MAJOR DUTIES & RESPONSIBILITIES:
- Lead end-to-end Data Management activities for one or more clinical studies with moderate guidance from the line manager.
- Supervise daily study-level data management operations, ensuring compliance with timelines and data integrity.

