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Associate Director of Program Leadership & Management

Deciphera Pharmaceuticals, Inc.

Full-time|On-site|Waltham

Deciphera Pharmaceuticals is excited to invite applications for the role of Associate Director of Program Leadership & Management. In this pivotal position, you will provide exceptional leadership and strategic direction to our Development and Commercial Program Teams. Collaborating closely with the Program Lead, you will be instrumental in advancing program…

Nov 17, 2025

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Director of Brand Leadership

Deciphera Pharmaceuticals

Full-time|On-site|Waltham

As the Director of Brand Leadership at Deciphera Pharmaceuticals, you will play a pivotal role in shaping the marketing strategies within our Hematology portfolio. Reporting directly to the VP of Marketing, Sales, and Commercial Training, you will spearhead a dynamic Marketing Team focused on crafting and executing innovative brand strategies.Key ResponsibilitiesFormulating a Comprehensive Strategic Brand Plan (50%)Collaborate with cross-functional teams to design an all-encompassing pre-launch and launch strategy.Create robust brand strategies and promotional plans targeting both healthcare professionals (HCPs) and patients across various platforms.Lead the Launch Readiness initiatives in a cross-functional capacity.Inspire and mobilize the entire commercial team and cross-functional partners to ensure alignment with our commercial strategy and to execute impactful customer outreach aligned with brand objectives.Manage the Product Marketing Team (40%)Ensure cohesive marketing strategies across all marketing colleagues to meet brand objectives effectively.Supervise one direct report to drive commercial success for the product while providing coaching and mentorship to develop our future talent in the Hematology Franchise.Serve as the Commercial Representative for Product Life Cycle Management (10%)Work in tandem with product program teams and Medical Affairs to contribute insights on studies, publications, and the identification and engagement of Key Opinion Leaders (KOLs).Additional duties and responsibilities as assigned

Feb 24, 2026

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Associate Director of Statistical Programming - Permanent Hybrid Role

ClinChoice

Full-time|Hybrid|United States

Are you looking for an opportunity to work closely with a single sponsor while benefiting from the stability and growth opportunities provided by a global CRO? Join our team at ClinChoice, where we believe it's the best of both worlds. ClinChoice is actively seeking an Associate Director of Statistical Programming for a permanent position in a hybrid work model. This role offers a unique chance to lead crucial statistical strategies within a vibrant and fast-paced environment. This position is hybrid, preferably requiring candidates to travel to our client’s location in Waltham, MA. We are looking for a seasoned Associate Director of Programming to spearhead programming initiatives, develop scalable processes, and guarantee the delivery of high-quality outputs for regulatory submissions.

Feb 5, 2026

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Program Manager

Integrated Resources, Inc.

Full-time|On-site|Waltham

We are seeking a dedicated and dynamic Program Manager to join our team at Integrated Resources, Inc. in Waltham, Massachusetts. As a Program Manager, you will play a crucial role in leading and coordinating various projects, ensuring they are executed efficiently and effectively. Your expertise will help drive our initiatives forward, fostering collaboration across teams and stakeholders.

Feb 22, 2017

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Director of Partner Programs

Xometry

Full-time|$150K/yr - $196K/yr|On-site|Waltham, MA

At Xometry (NASDAQ: XMTR), we bridge the gap between visionary creators and the manufacturing powerhouses that turn their concepts into reality. Our dynamic digital marketplace equips manufacturers with essential resources to scale their businesses while enabling Fortune 1000 buyers to access unparalleled global manufacturing capabilities.As the Director of Partner Programs, you will play a pivotal role in orchestrating the synergy between Product, Operations, Finance, Marketing, Partner Success, and Leadership. Your mission will be to craft the strategy for expanding and refining Xometry's supplier network, overseeing key phases from acquisition and onboarding to engagement and retention.You will establish the vision, formulate the strategy, and manage initiatives designed to enhance our supplier base. Leading a focused team, you will collaborate closely with cross-functional partners to achieve tangible business results.

Feb 2, 2026

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Director of Strategic Programs

Evolv Technology

Full-time|$138K/yr - $222K/yr|On-site|Waltham, Massachusetts, United States

Elevator PitchThe Director of Strategic Programs serves as a vital strategic ally to the CFO, overseeing comprehensive project management that includes M&A sourcing through integration, implementing change management for system upgrades, prioritizing budgets, and leading an enterprise PMO that facilitates transformative initiatives across the organization. In this role, you will be instrumental in managing the CFO’s operational framework, spearheading critical company-wide programs, and conducting business reviews focused on ROI that align with C-Suite objectives.Success in the Role (First 6–12 Months)In the first 30 days, you will:Establish strong connections with key stakeholders and partners, including the Executive Leadership Team, Finance, and other senior leaders.Align with CFO priorities, business rhythms, and the operational calendar (planning, forecasts, ELT/Board cycles, etc.).Implement functional reviews for strategic initiatives and budget planning.Within 90 days, you will:Initiate the organic investment review (ROIC model, tiered scorecards) to inform start/stop/continue decisions.Set up the Enterprise PMO cadence across IT projects, Contract Manufacturing change management, M&A funnel, and targeted value projects (e.g., software subscription expenditure reduction, indirect procurement, off-shoring).By the end of 12 months, you will:Deliver quantifiable ROI productivity (portfolio rebalanced; ROIC enhancement; cycle time reduction).Advance at least one M&A transaction through the stage gate process with a comprehensive Post Merger Integration plan.Achieve key transformation milestones with KPI improvements aligned with company objectives.Ensure service SLAs are met; maintain CFO time alignment above 85% on top priorities.The Work (What You’ll Do):Strategy & Internal Capital InvestmentLead the annual and long-range planning process alongside the CFO and CEO; translate strategic objectives into OKRs and decision memos.Manage internal operations and organic investment reviews utilizing ROIC/NPV scorecards; recommend rebalancing actions and ensure follow-through with the ELT.Collaborate with the ELT and junior staff across all functions to achieve related company goals.M&A / Corporate DevelopmentDevelop theses and maintain a target pipeline with the ELT; ensure consistent deal cadence and reporting.

Jan 15, 2026

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Associate Director/Director of Analytical & GMP Quality Assurance Operations

Crescent Biopharma

Full-time|On-site|Waltham, MA

At Crescent Biopharma, we aspire to transform the landscape of oncology by developing cutting-edge therapies tailored for cancer patients. Our innovative pipeline includes a leading PD-1 x VEGF bispecific antibody, alongside state-of-the-art antibody-drug conjugates. By harnessing diverse therapeutic modalities and established targets, we aim to expedite the development of potentially groundbreaking treatments, whether as standalone interventions or in combination therapies targeting various solid tumors. For more insights into our mission and vision, visit our website and connect with us on LinkedIn and X.We are currently in search of an Associate Director or Director of Analytical & GMP Quality Assurance Operations. In this pivotal role, you will oversee and guide the QA functions related to analytical development, quality control operations, and GMP quality activities across our clinical-stage biologics and ADC programs. Collaboration with cross-functional teams, including CMC, Analytical Sciences, Quality Control, and Technical Operations, as well as external manufacturing and testing partners, will be key to ensuring compliance with phase-appropriate GMP standards, maintaining data integrity, and ensuring inspection readiness within a dynamic outsourced operational framework. Your strategic vision will be instrumental in shaping Crescent's analytical quality strategy and driving the disciplined execution of core quality systems that align with our aggressive development timelines.

Mar 10, 2026

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Associate Director, Pharmacovigilance Scientist

Deciphera Pharmaceuticals, Inc.

Full-time|On-site|Waltham

As the Associate Director of Pharmacovigilance, you will play a crucial role in ensuring the safety and efficacy of our pharmaceutical products. You will lead a team dedicated to monitoring and evaluating adverse drug reactions, while also collaborating closely with regulatory bodies to uphold our commitment to patient safety. Your expertise will contribute significantly to our ongoing efforts in drug development and post-marketing surveillance. Join us in making a difference in the lives of patients around the world.

Apr 6, 2026

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Associate Director of Access Strategy

Sobi

Full-time|On-site|Waltham

As the Associate Director of Access Strategy at Sobi, you will play a pivotal role in shaping the strategies that enhance patient access to our innovative therapies. This position requires a strategic thinker who is passionate about improving healthcare accessibility and is adept at navigating the complexities of the healthcare landscape. You will work closely with cross-functional teams to develop and implement access strategies that align with our organizational goals and promote patient-centric outcomes.

Apr 30, 2026

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Associate Director, Regulatory Affairs CMC

AbbVie Inc.

Full-time|On-site|Waltham

Join AbbVie as an Associate Director in Regulatory Affairs with a focus on Chemistry, Manufacturing, and Controls (CMC). In this pivotal role, you will lead cross-functional teams to ensure compliance with regulatory requirements while advancing our innovative therapies. As a leader, you will drive the development of CMC submission strategies, collaborate with internal and external stakeholders, and support the overall regulatory strategy for our product pipeline.

Apr 30, 2026

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Associate Director of Sales Operations

Deciphera Pharmaceuticals, Inc.

Full-time|On-site|Waltham

Deciphera Pharmaceuticals, Inc. is on the lookout for a seasoned Associate Director of Sales Operations to spearhead and enhance our field-facing operational strategies. This pivotal role will support the establishment of a high-performing Commercial field team, particularly focused on facilitating a successful brand launch. The successful candidate will ensure compliance, efficiency, and data-driven insights within field operations across our Hematology Franchise, playing a crucial role in ensuring operational readiness for product launches and ongoing excellence initiatives in the field.Key ResponsibilitiesFormulate and implement field operations strategies that align with both commercial and medical objectives.Manage field technology platforms including CRM systems, roster management, and reporting tools in collaboration with the IT department.Oversee territory design, roster management, and alignment processes to ensure compliance with coverage models.Coordinate onboarding operations with Training, HR, and Compliance teams.Direct the creation of field reports, dashboards, KPI tracking, and business insights.Ensure all field operations processes adhere to FDA, OIG, and corporate compliance standards.Lead continuous improvement initiatives aimed at enhancing scalability, efficiency, and quality.Collaborate effectively across functions including Sales, Marketing, Medical, Compliance, IT, HR, Legal, and Finance.

Feb 25, 2026

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Associate Director of Clinical Operations

Oruka Therapeutics

Full-time|$182K/yr - $208K/yr|Hybrid|Waltham, Massachusetts, United States

Oruka Therapeutics is developing biologics designed to change the treatment landscape for chronic skin conditions such as plaque psoriasis. The company focuses on long-lasting relief for patients, aiming for outcomes like disease clearance with infrequent dosing. Their pipeline includes proprietary antibodies created by Paragon Therapeutics, targeting the underlying causes of dermatologic and inflammatory diseases. More details about their work can be found at www.orukatx.com. Role overview The Associate Director of Clinical Operations will manage the setup and execution of clinical trials, supporting the Director of Clinical Operations within a specific therapeutic area. This position oversees multiple studies, combining strategic planning with day-to-day operational involvement to keep clinical programs on track and within budget. Responsibilities include handling operational details, anticipating challenges, and implementing solutions to ensure trial progress. The role requires someone who can move between leadership and hands-on work, maintaining a player/coach mindset throughout. What you will do Oversee all phases of clinical trial setup and execution across several studies Support the Director of Clinical Operations in a designated therapeutic area Balance strategic planning with direct, hands-on involvement in daily operations Identify and resolve operational challenges to maintain study timelines and budgets Requirements Demonstrated integrity and sound judgment in clinical operations Ability to shift between high-level oversight and direct involvement as needed Strong commitment to study goals and a collaborative approach Adaptability and resourcefulness in a biotech setting This hybrid role is based in Waltham, Massachusetts, with an expectation of three days onsite each week. The team values learning, growth, and a positive, inclusive culture.

Apr 22, 2026

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Human Resources Program Manager

Xometry

Full-time|On-site|Waltham, MA

Xometry is seeking a dynamic and experienced Human Resources Program Manager to join our team in Waltham, MA. In this role, you will be responsible for driving HR initiatives that support our business objectives, enhance employee engagement, and foster a high-performance culture.Your expertise in managing HR programs will be essential in developing strategies to attract, retain, and develop top talent. You will collaborate with various departments to implement best practices in talent management, performance evaluation, and employee development.

Feb 26, 2026

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Associate Director, CMC-Pharma Product Group

AbbVie Inc.

Full-time|On-site|Waltham

Join AbbVie as an Associate Director in our CMC-Pharma Product Group, where you will play a pivotal role in leading cross-functional teams to drive the development and manufacturing of high-quality pharmaceutical products. Your expertise will be crucial in ensuring compliance with regulatory standards and enhancing our product portfolio.

May 1, 2026

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Associate Director, Downstream, Manufacturing Sciences and Technology (Biologics)

Oruka Therapeutics

Full-time|$175K/yr - $200K/yr|Hybrid|Waltham, Massachusetts, United States

About Us:Oruka Therapeutics (Nasdaq: ORKA) is at the forefront of developing innovative biologics aimed at revolutionizing the treatment of chronic skin disorders. Our mission is to empower patients suffering from conditions such as plaque psoriasis by providing opportunities for significant disease clearance with minimal dosing frequency, potentially just once or twice a year. Leveraging a unique portfolio of advanced antibodies engineered by Paragon Therapeutics, we target the fundamental mechanisms contributing to plaque psoriasis and other dermatologic and inflammatory conditions. Learn more about our vision at www.orukatx.com.As we expand our core team, we are seeking passionate professionals who aspire to be part of a transformative journey, not just a job. If you are eager to make a positive impact and contribute to a vibrant, inclusive company culture, we want to hear from you.Job Title: Associate Director, Downstream, Manufacturing Sciences and Technology (Biologics)Location: Hybrid – Waltham, MA, with a requirement to be in-office 3 days a week.Position Overview:We are looking for a dynamic and skilled leader in Manufacturing Science and Technology (MSAT) to spearhead downstream late-stage and pivotal optimization, scale-up, and transfer of manufacturing processes. In this role, you will be responsible for process development, troubleshooting production challenges, data analysis, and ensuring adherence to regulatory standards to uphold product quality. The successful candidate will play a critical role in late-stage drug substance manufacturing and process validation activities to support BLA submissions. This position requires adaptability in a fast-paced environment, along with the ability to draft high-quality reports, finalize source documents, and actively participate in regulatory submissions. Join us as a vital member of a growing team dedicated to advancing best-in-class biotherapeutics.

Mar 30, 2026

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Associate Director of Financial Planning & Analysis

Crescent Biopharma

Full-time|On-site|Waltham, MA

The Associate Director of Financial Planning & Analysis at Crescent Biopharma is based in Waltham, MA. This role plays a key part in shaping financial planning at both the corporate and program levels, with a focus on budgeting and forecasting. Role overview This position partners with teams across the company, including R&D and Program Management. The Associate Director helps guide financial decisions that support Crescent Biopharma’s strategic goals and ongoing projects. What you will do Lead corporate and program-level budgeting and forecasting processes Collaborate with cross-functional teams to provide financial insight and analysis Support strategic planning by delivering accurate financial data and recommendations Location This role is located in Waltham, MA.

Apr 21, 2026

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Senior Engineering Program Manager

Boston Engineering Corporation

Full-time|On-site|Waltham

Role overview The Senior Engineering Program Manager at Boston Engineering Corporation oversees projects from early concept stages to final delivery. Based in Waltham, this position manages the full project lifecycle, ensuring that engineering teams stay aligned with client needs and expectations. Success in this role depends on strong coordination with cross-functional groups. The Senior Engineering Program Manager works closely with colleagues across disciplines to keep projects on track and deliver solutions that meet specific client requirements. Key responsibilities Lead engineering projects from concept through completion Coordinate with teams across functions to ensure effective project execution Focus on delivering solutions that address each client’s requirements Location This role is based in Waltham.

Apr 21, 2026

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Associate Scientific Director, Translational Precision Medicine - Neuroscience

AbbVie

Full-time|On-site|Waltham

Purpose:As an Associate Scientific Director in Translational Precision Medicine within Neuroscience, you will play a pivotal role in bridging fundamental research on the brain and nervous system with clinical applications. Your focus will be on advancing insights into biological mechanisms and disease processes related to neurological and psychiatric disorders.Responsibilities:In this role, you will uncover neurobiological mechanisms associated with disease, elucidate patient subtypes, and advance the development of innovative interventions. Your key responsibilities include:Formulating testable hypotheses concerning neurobiological pathways, neuronal circuitry, cognitive or behavioral aspects, and functional markers of disease or patient groups to propel pipeline and disease area objectives. Collaborate seamlessly with PMed DAS leads and other functional leaders to create and implement operationally robust strategies that yield actionable results.Enhancing human neuroscience initiatives by fostering research synergies across R&D sectors, aligned with strategic disease area objectives. This includes:Driving the scientific strategy for developing translational biomarkers and validating discovery targets through mechanism of action (MOA) projects.Leading the design of clinically translational experiments in partnership with PMED, clinical leads, or discovery research translational teams to meet strategic goals in the disease area.Forging external collaborations to supplement internal translational efforts and broaden experimental design possibilities.Ensuring the quality and effectiveness of major project plans within precision medicine via sound design and proactive risk assessment.Advancing clinical translational initiatives through alignment with stakeholders and leadership while navigating current and future business challenges to achieve objectives.Sharing scientific expertise and insights by proactively advising and engaging with team members, peers, and upper management.Identifying and leveraging emerging scientific trends from both within and outside the organization to stay ahead and enhance standards in the field of translational neuroscience.

May 4, 2026

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Director of HOVA

Sobi

Full-time|On-site|Waltham

Role Overview Sobi is hiring a Director of HOVA to guide the strategic and operational direction of HOVA projects in Waltham. This leader will shape priorities, manage execution, and ensure projects support Sobi’s mission to improve healthcare outcomes. Key Responsibilities Oversee HOVA project strategy and daily operations Align initiatives with company goals and mission Promote collaboration across teams and departments Support growth and strengthen Sobi’s position in the market

Apr 19, 2026

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Program Manager, Operations at Xometry | Waltham, MA

Xometry

Full-time|$103K/yr - $134K/yr|On-site|Waltham, MA

Xometry (NASDAQ: XMTR) is at the forefront of empowering the industries of today and tomorrow by connecting visionary thinkers with manufacturers capable of turning their ideas into reality. Our digital marketplace equips manufacturers with essential resources for business growth while facilitating effortless access to global manufacturing capabilities for buyers at Fortune 1000 companies.We are on the lookout for a highly motivated and experienced Program Manager, Operations to become a vital part of our dynamic and innovative team. This role is pivotal in managing cross-functional initiatives aimed at improving operational efficiency, enhancing scalability, and propelling our growth in advanced manufacturing. Candidates with a background in the automotive or manufacturing industry will be given priority.

Feb 2, 2026

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