Scientist, Genome Editing Technologies - Hsu Lab

Arc InstitutePalo Alto, CA

On-site Full-time $121.3K/yr - $159.5K/yr

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Experience Level

Experience

Qualifications

We are seeking candidates with a strong background in molecular biology, genetics, or a related field. A PhD is preferred, along with hands-on experience in genome editing technologies. Candidates should demonstrate a passion for scientific inquiry, collaboration, and the ability to thrive in a dynamic research environment.

About the job

About Arc Institute

The Arc Institute is a pioneering scientific organization dedicated to curiosity-driven research and technological advancements aimed at understanding and treating complex human diseases. Based in Palo Alto, California, Arc operates as an independent research entity, collaborating with prestigious partners such as Stanford University, UCSF, and UC Berkeley.

At Arc, we believe in the power of innovative institutional models to advance critical research initiatives. Our approach emphasizes:

Funding: We provide comprehensive funding to our Core Investigators, allowing them to focus on groundbreaking research without the constraints of traditional project-based external grants.
Technology: As biomedical research increasingly relies on sophisticated tools, our Technology Centers collaborate with Core Investigators to develop, optimize, and implement cutting-edge experimental and computational technologies.
Support: We strive to offer exceptional operational, financial, and scientific support, empowering researchers to embark on high-risk, high-reward projects that aim to make significant strides in curing diseases such as neurodegeneration, cancer, and immune dysfunction.
Culture: We prioritize creating a culture of scientific curiosity, unwavering commitment to truth, broad ambition, and selfless collaboration, which we believe are essential for sustaining excellence in research.

With a thriving community of over 350 staff members and more than $650 million in committed funding, our state-of-the-art laboratory in Palo Alto positions Arc for rapid growth in the years ahead.

About the Position

The Hsu Lab invites applications for a Scientist role focused on the development and application of innovative genome editing technologies. Our recent discovery of Bridge Recombinases, naturally occurring RNA-guided DNA recombinases that can programmatically insert, excise, and invert DNA, marks a significant advancement in the field (Nature, 2024 and Science, 2025). The selected candidate will lead the next phase of Bridge Recombinase evolution, building on our progress with IS110 and ISCro4 as programmable tools.

About Arc Institute

The Arc Institute is revolutionizing scientific research by fostering collaboration and innovation in the pursuit of understanding and treating complex human diseases. With strong partnerships and a commitment to supporting cutting-edge research, Arc is setting a new standard for research institutions.

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