Vice President of US Market Access

As the Director of Market Access Pricing & Analytics, you will play a pivotal role within our US Market Access team. This leadership position is essential for delivering impactful insights that shape our pricing, contracting, and reimbursement strategies. You will leverage advanced analytics, strategic acumen, and cross-functional collaboration to support ke…

Zenas BioPharma is a pioneering clinical-stage biopharmaceutical company dedicated to becoming a frontrunner in the development and commercialization of groundbreaking therapies aimed at treating autoimmune diseases. Our strategic approach combines the expertise of our seasoned leadership team with a focused product candidate acquisition strategy to identify, acquire, and develop globally impactful product candidates that can deliver exceptional clinical benefits to patients affected by autoimmune conditions. Currently, Zenas is advancing two late-stage molecules, obexelimab and orelabrutinib. Obexelimab, our leading candidate, is a bifunctional monoclonal antibody targeting CD19 and FcγRIIb, crucial components in the B cell lineage, designed to inhibit the activity of specific cells involved in autoimmune disorders without depleting them. We believe that obexelimab’s innovative mechanism and self-administered, subcutaneous injection method will effectively address the pathogenic role of B cells in chronic autoimmune diseases. Orelabrutinib is a highly selective, CNS-penetrant oral Bruton’s Tyrosine Kinase (BTK) inhibitor that shows promise in managing compartmentalized inflammation and disease progression in Multiple Sclerosis (MS). Our earlier-stage projects include a preclinical oral IL-17AA/AF inhibitor and a preclinical oral brain-penetrant TYK2 inhibitor.We are in search of exceptional talent who share our passion for patient care and possess a proven track record in acquiring, developing, and commercializing global products. Joining Zenas offers the opportunity to thrive in a dynamic learning environment and achieve personal and organizational success as we strive to become a leader in immunology and autoimmune disease treatment, while upholding our values of Transparency, Relationships, Urgency, Excellence, and Innovation—embracing TRUE Innovation!Position Summary:The Senior Director of Pricing and Contracting will spearhead the development and implementation of the U.S. pricing and contracting strategy to ensure optimal market access, reimbursement, and financial performance for Zenas BioPharma’s portfolio. This role includes crafting contracting strategies with national and regional payer organizations, pharmacy benefit managers (PBMs), and government payers. Reporting directly to the Vice President of U.S. Market Access, the individual will oversee pricing strategy formulation, gross-to-net modeling, and payer contracting strategies that will support both product launch initiatives and lifecycle management.

As the Associate Director of Access Strategy at Sobi, you will play a pivotal role in shaping the strategies that enhance patient access to our innovative therapies. This position requires a strategic thinker who is passionate about improving healthcare accessibility and is adept at navigating the complexities of the healthcare landscape. You will work closely with cross-functional teams to develop and implement access strategies that align with our organizational goals and promote patient-centric outcomes.

Xometry (NASDAQ: XMTR) is at the forefront of innovation, connecting visionary individuals with the manufacturers who can transform their concepts into reality. Our digital marketplace equips manufacturers with essential resources for growth while facilitating access to global manufacturing capabilities for Fortune 1000 companies.As the Director of Marketplace Marketing, you will play a pivotal role in shaping and executing go-to-market strategies for two vital segments of Xometry’s operations: enhancing growth within the U.S. Marketplace (Buyer-focused) and expanding our Global Partner network (Supplier-focused). This position requires a strategic thinker and hands-on leader who can set a compelling vision while actively participating in the execution of impactful marketing initiatives.Your role will center on grounding marketing activities in genuine market insights and maintaining a disciplined focus on return on investment (ROI). You will ensure that buyer acquisition strategies and partner engagement programs are informed by real-world feedback, optimized for measurable performance, and drive significant business results.

About Us:Oruka Therapeutics (Nasdaq: ORKA) is pioneering innovative biologic therapies aimed at transforming the treatment landscape for chronic skin conditions. Our mission is to empower individuals suffering from chronic skin diseases, such as plaque psoriasis, by providing unprecedented freedom from their ailments through treatments administered as infrequently as once or twice a year. We are advancing a proprietary portfolio of potentially best-in-class antibodies developed by Paragon Therapeutics, targeting the fundamental mechanisms of plaque psoriasis and other dermatological and inflammatory disorders. For more details, visit www.orukatx.comAs we fortify our core team, we are on the lookout for exceptional talent across various domains. We seek individuals who are not just looking for employment, but are eager to contribute to a larger purpose. If you are passionate about making a significant impact and are keen on fostering an engaged, inclusive, and positive workplace culture, we want to hear from you.Job Title: Associate Director/Director of Analytical Development and Validation - Tech Operations (Biologics)Location: Hybrid – Waltham, MA. Candidates are expected in the office 3 days a week. Remote considerations may apply.Role Overview:The Associate Director/Director of Analytical Development and Validation will provide scientific and strategic leadership for late-stage analytical activities that support the development, validation, and lifecycle management of biologic drug products, particularly monoclonal antibodies. This position will oversee method validation and comparability initiatives essential for BLA/MAA submissions, process modifications, and commercial readiness, collaborating closely with CMC, Quality, Regulatory Affairs, and external partners.The ideal candidate is a proactive leader with extensive experience in analytical method validation, device functional testing, and regulatory frameworks for late-stage biologics. You will guide teams through intricate technical and compliance milestones, making this a highly visible role within the CMC team. Join our expanding organization and play a crucial part in supporting multiple programs’ analytical activities, facilitating the release of supplies for clinical trials, and preparing for commercialization in the US, Canada, and EU.

Who We Are:Cogent Biosciences is a publicly traded biotechnology firm dedicated to pioneering innovative precision therapies aimed at addressing diverse patient needs in the medical field. Our flagship program, bezuclastinib, is engineered to selectively and effectively inhibit exon 17 mutations present in the KIT receptor tyrosine kinase, notably including KIT D816V. This mutation is a primary driver of Systemic Mastocytosis, a rare and serious disease, while exon 17 mutations are also implicated in gastrointestinal stromal tumors (GIST), a cancer type reliant on aberrant KIT signaling. Bezuclastinib has demonstrated promising outcomes in early trials: APEX in AdvSM, SUMMIT in NonAdvSM, and PEAK in GIST, showcasing a favorable safety profile across more than 600 patients in both standalone and combination therapies.Position Overview:The National Account Director (NAD) is tasked with securing profitable coverage access with national payer organizations, including GPOs, PBMs, and major regional account clients.This role is pivotal in executing our Market Access objectives and strategies directed at the payer audience.The NAD will collaborate with various internal teams such as Market Access, Marketing, Commercial Operations, Sales, and Medical to align strategies with our key clients, ensuring optimal experiences for both patients and providers.Key Responsibilities:Implement tailored customer strategies that align with our overall product and business objectives.Communicate the value of our offerings by managing relationships with all customer stakeholders.Design and execute corporate strategies tailored to the market access payer landscape, maximizing Cogent's access and profitability.Lead discussions with key strategic accounts, including clinical and contracting negotiations as necessary.Stay informed on developments among government and private insurers to inform Market Access strategies, enabling proactive responses to market changes.Establish, nurture, and expand relationships with senior executives at key accounts.

About Us: At Cogent Biosciences, we are a pioneering biotechnology firm publicly traded and focused on creating precision therapies for genetically defined diseases. Utilizing validated biology and a strategic drug discovery approach, we strive to offer authentic solutions that tackle the core mechanisms of diseases, providing genuine hope to patients. Our flagship therapeutic candidate, bezuclastinib, is a highly selective tyrosine kinase inhibitor that effectively targets KIT D816V and other mutations found in KIT exon 17. These mutations are pivotal in the progression of systemic mastocytosis (SM) and advanced gastrointestinal stromal tumors (GIST), both critical conditions driven by oncogenic KIT signaling. Currently, bezuclastinib is undergoing evaluation in numerous clinical trials aimed at registration for Non-Advanced SM, Advanced SM, and GIST. In July 2025, we proudly announced the statistical significance of our registration-directed SUMMIT trial in NonAdvSM patients, with plans to submit our first New Drug Application for this demographic by the end of 2025. Furthermore, we anticipate releasing top-line results for our APEX trial concerning AdvSM and for our PEAK trial with GIST by the close of 2025. Our dedicated research team is also advancing a Phase 1 study of a novel FGFR2 inhibitor, while developing a portfolio of innovative therapies targeting other serious, genetically driven diseases, including mutations in ErbB2, PI3Kα, and KRAS. Committing to precision medicine and targeted innovation, Cogent Biosciences aims to revolutionize the treatment landscape for patients grappling with severe and underserved diseases. Our culture promotes inquisitiveness, fostering continuous learning and innovation, as we challenge norms, pose bold inquiries, and embrace a discovery mindset to unveil transformative insights. Your Role: This key position reports directly to the Vice President of Marketing and represents a unique opportunity for candidates eager to join a company on the cusp of its inaugural product launch, backed by compelling data in rare disease and oncology sectors. You will lead the groundbreaking launch of Bezuclastinib for the 2L Gastrointestinal Stromal Tumor (GIST) indication, marking the most significant advancement in GIST in the past two decades. The Senior Director of Marketing will be recognized as an internal authority on GIST disease, market dynamics, and promotional strategies.

Constant Contact is hiring a Director of Full Stack Growth Marketing. This leadership role guides the development and execution of marketing strategies aimed at driving company growth and improving customer experience. Role overview The Director will shape the overall marketing approach by integrating data analysis with creative planning. The focus is on optimizing the entire marketing stack to support business goals and customer needs. Key responsibilities Lead the design and implementation of innovative marketing strategies Use data-driven insights to inform decision-making and measure impact Enhance customer experience through targeted marketing initiatives Oversee optimization across all marketing channels and tools Location This position can be based in Waltham, MA or performed remotely.

Who We Are: Cogent Biosciences is a leading biotechnology company publicly traded and dedicated to developing innovative precision therapies to address significant medical needs. Our flagship program, bezuclastinib, effectively targets exon 17 mutations in the KIT receptor tyrosine kinase, including the KIT D816V variant, which is linked to Systemic Mastocytosis and gastrointestinal stromal tumors (GIST). With encouraging data from multiple clinical trials, including APEX, SUMMIT, and PEAK, bezuclastinib demonstrates a strong safety profile and potential for positive patient outcomes. The Role: We are looking for compassionate and driven Patient Access Navigators to pioneer our Patient Services team. As a Patient Access Navigator, you will be instrumental in providing a comprehensive, patient-centered access experience throughout the prescription fulfillment process. You will manage the entire patient journey in your designated geographic area and collaborate closely with patients, caregivers, healthcare providers (HCPs), specialty pharmacies, and internal and external partners to ensure timely access to therapies and continuity of care. Although this role is primarily home-based with occasional office visits at our Waltham Headquarters (two days a week), you will be expected to support complex access, reimbursement, or care coordination needs as required. We seek team members who are empathetic, detail-oriented, and committed to operational excellence as we prepare for the launch of bezuclastinib.

At Crescent Biopharma, we aspire to transform the landscape of oncology by developing cutting-edge therapies tailored for cancer patients. Our innovative pipeline includes a leading PD-1 x VEGF bispecific antibody, alongside state-of-the-art antibody-drug conjugates. By harnessing diverse therapeutic modalities and established targets, we aim to expedite the development of potentially groundbreaking treatments, whether as standalone interventions or in combination therapies targeting various solid tumors. For more insights into our mission and vision, visit our website and connect with us on LinkedIn and X.We are currently in search of an Associate Director or Director of Analytical & GMP Quality Assurance Operations. In this pivotal role, you will oversee and guide the QA functions related to analytical development, quality control operations, and GMP quality activities across our clinical-stage biologics and ADC programs. Collaboration with cross-functional teams, including CMC, Analytical Sciences, Quality Control, and Technical Operations, as well as external manufacturing and testing partners, will be key to ensuring compliance with phase-appropriate GMP standards, maintaining data integrity, and ensuring inspection readiness within a dynamic outsourced operational framework. Your strategic vision will be instrumental in shaping Crescent's analytical quality strategy and driving the disciplined execution of core quality systems that align with our aggressive development timelines.

Zenas Bio is a pioneering clinical-stage global biopharmaceutical firm dedicated to advancing transformative therapies for individuals afflicted with autoimmune disorders. Our strategic approach blends experienced leadership with a meticulous product acquisition strategy, enabling us to identify, acquire, and develop promising product candidates worldwide that aim to deliver exceptional clinical benefits to patients battling autoimmune diseases. Currently, we are progressing two late-stage potential franchise molecules: obexelimab and orelabrutinib. Obexelimab, our flagship product, is a bifunctional monoclonal antibody designed to bind both CD19 and FcγRIIb, which are prevalent across B cell lineages, effectively inhibiting the activity of cells implicated in various autoimmune diseases while preserving them. We believe that obexelimab’s innovative mechanism of action and its self-administered subcutaneous injection regimen will significantly address the pathogenic role of B cell lineage in chronic autoimmune diseases. Orelabrutinib is a potentially best-in-class, highly selective CNS-penetrant oral small molecule Bruton’s Tyrosine Kinase (BTK) inhibitor that holds promise for addressing compartmentalized inflammation and disease progression in Multiple Sclerosis (MS). Additionally, our earlier-stage programs include a preclinical, potentially best-in-class oral IL-17AA/AF inhibitor and a preclinical oral brain-penetrant TYK2 inhibitor.We are in search of exceptional talent who shares our dedication to patients and possesses a proven track record in acquiring, developing, and commercializing products on a global scale. Our team enjoys the opportunity to thrive in a dynamic learning environment, achieving both personal and organizational success as we strive to become a global leader in immunology and autoimmune diseases, guided by our core values of Transparency, Relationships, Urgency, Excellence, and Innovation – TRUE Innovation!Position Summary:Zenas is on the lookout for a seasoned and dynamic commercial leader with extensive experience in Immunology and Inflammation (I&I) and a deep understanding of the US market to spearhead the HCP Brand Marketing strategy and initiatives. Reporting directly to the VP Head of Marketing, the Senior Director, HCP Marketing Lead will be responsible for driving the HCP marketing strategy for Obexelimab, with a focus on the launch of its first indication in IgG4-Related Disease. This role will involve establishing a customer-centric vision and achieving high performance standards. The leader will oversee all aspects of brand positioning, messaging, and resource prioritization while ensuring alignment with cross-functional partners. This pivotal role will be crucial to the company's ongoing success.

About Vita Global SciencesAt Softworld's Vita Global Sciences, we excel in providing professional services tailored to the life sciences sector. Our expertise includes clinical data analytics solutions and functional outsourcing services. Our dedicated team is skilled in Clinical Data Management, Regulatory Submissions, Biostatistics, Statistical Programming, Data Analytics, and PK/PD analysis. We pride ourselves on our steadfast commitment to delivering outstanding results in a safe, compliant, and efficient manner.Our Ideal Candidate:We are looking for a dynamic Director of Business Development to lead the growth of our Life Sciences division from a remote setting. The successful candidate will adeptly manage geographic territories, identify and cultivate promising leads, craft persuasive proposals, and deliver influential presentations. Our primary focus is to provide exceptional consulting services to our esteemed clients. This role demands a high degree of professionalism and expertise, and we are excited to find an individual who can significantly contribute to achieving our objectives.

As the Director of Brand Leadership at Deciphera Pharmaceuticals, you will play a pivotal role in shaping the marketing strategies within our Hematology portfolio. Reporting directly to the VP of Marketing, Sales, and Commercial Training, you will spearhead a dynamic Marketing Team focused on crafting and executing innovative brand strategies.Key ResponsibilitiesFormulating a Comprehensive Strategic Brand Plan (50%)Collaborate with cross-functional teams to design an all-encompassing pre-launch and launch strategy.Create robust brand strategies and promotional plans targeting both healthcare professionals (HCPs) and patients across various platforms.Lead the Launch Readiness initiatives in a cross-functional capacity.Inspire and mobilize the entire commercial team and cross-functional partners to ensure alignment with our commercial strategy and to execute impactful customer outreach aligned with brand objectives.Manage the Product Marketing Team (40%)Ensure cohesive marketing strategies across all marketing colleagues to meet brand objectives effectively.Supervise one direct report to drive commercial success for the product while providing coaching and mentorship to develop our future talent in the Hematology Franchise.Serve as the Commercial Representative for Product Life Cycle Management (10%)Work in tandem with product program teams and Medical Affairs to contribute insights on studies, publications, and the identification and engagement of Key Opinion Leaders (KOLs).Additional duties and responsibilities as assigned

The Medical Excellence Manager will play a pivotal role in overseeing Investigator Sponsored Studies (ISS), Managed Access Programs (MAP), and Post Trial Access (PTA) Programs. The successful candidate will be tasked with:Managing the ISS review and approval process, ensuring thorough proposal validation, coordination of reviews, and effective communication of decisions to stakeholders.Oversight of the MAP/PTA review and approval process, which includes coordinating case reviews, documenting decisions, and engaging with relevant parties.Acting as the global point of contact for ISS and MAP management concerning specified products, collaborating with cross-functional internal and external stakeholders.Maintaining detailed databases for ISS and MAP/PTA, meticulously tracking proposals, studies, and decisions along with necessary documentation.Facilitating contract development and negotiations between sponsors/requestors and Sobi, working closely with legal and other departments as necessary.Supporting supply chain setup in partnership with Affiliate teams and Sobi Supply Chain for both ISS and MAP/PTA programs.Providing regular status updates on ISS and MAP/PTA programs to relevant teams and leadership.Monitoring milestone payments and reporting the ISS budget to budget owners.Coordinating with vendors for the setup and management of MAP and PTA programs as needed.

About Us: Cogent Biosciences is a publicly traded biotechnology firm dedicated to pioneering innovative precision therapies aimed at addressing significant medical needs across diverse patient populations. Our flagship product, bezuclastinib, is engineered to effectively inhibit exon 17 mutations in the KIT receptor tyrosine kinase, particularly the KIT D816V mutation, which is implicated in Systemic Mastocytosis and gastrointestinal stromal tumors (GIST). We have observed promising initial results from our clinical trials (APEX, SUMMIT, PEAK), showcasing a favorable safety profile across over 600 patients receiving both monotherapy and combination treatments. The Opportunity: We are seeking a dynamic individual for the pivotal role of Senior Manager/Associate Director of Marketing Operations. This position will oversee the execution of strategic marketing operations to facilitate the launch of bezuclastinib, ensuring efficient, compliant, and impactful delivery of promotional materials and omnichannel campaigns. You will work closely with brand leaders to create a unified promotional strategy that enhances customer experience, drives brand performance, and supports commercial growth. Key Responsibilities: Omnichannel Campaign Management: Collaborate with the marketing team to develop and implement complex customer engagement strategies across healthcare professionals, patients, and caregivers. Partner with analytics teams to incorporate insights into campaign design and continuous improvement. Ensure readiness of systems and platforms for tracking key performance metrics and campaign effectiveness. Utilize data and segmentation strategies to ensure personalized outreach to target audiences. Promotional Review and Content Approval: Oversee the internal promotional review process (MLR) and navigate the content approval path for key commercial materials.

About Constant Contact Constant Contact supports business owners, entrepreneurs, non-profits, and individuals as they build and grow their online presence. The team values integrity, initiative, and the entrepreneurial mindset. Every project aims to make a real difference for people working to achieve their goals. Role Overview The Senior Marketing Manager - Growth Lifecycle Marketing will take the lead in designing automated marketing workflows and applying AI-powered personalization. The goal: deliver tailored messages to the right audiences at the right moments. This role emphasizes rapid experimentation with new product offerings and revenue streams, testing ideas quickly before rolling out larger programs. What You Will Do Design and optimize automated marketing workflows across the customer lifecycle Use AI-driven personalization to increase engagement and conversion Test new product offerings and revenue opportunities through fast, iterative experimentation Scale successful initiatives to reach broader audiences Integrate new marketing technologies to support growth goals Who Thrives Here This position suits someone who enjoys strategic thinking, hands-on experimentation, and scaling what works. Curiosity about new marketing tools and a drive to make measurable impact are key. Location Waltham, MA or remote.

About Oruka Therapeutics Oruka Therapeutics (Nasdaq: ORKA) develops biologic therapies for chronic skin diseases, with a focus on achieving complete disease clearance for patients with conditions like plaque psoriasis. The company’s antibody portfolio, created in partnership with Paragon Therapeutics, targets the underlying mechanisms of dermatologic and inflammatory diseases. Oruka’s goal is to offer patients long-lasting relief, potentially with just one or two treatments per year. Learn more at www.orukatx.com. Position Details Title: Director/Senior Medical Director, Clinical Development (Multiple openings) Location: Remote or hybrid. For those near Waltham, MA or Menlo Park, CA, hybrid work is available (3 days per week in office). Role Overview The Director or Senior Medical Director, Clinical Development, leads and supports clinical trials across Oruka’s pipeline. This role shapes clinical study design, oversees trial execution, and interprets data to validate product safety and efficacy. Collaboration with internal teams and external partners is central, ensuring clinical activities align with regulatory, scientific, and business goals. Main Responsibilities Clinical Trial Design and Oversight: Help develop clinical trial protocols, including patient selection, study endpoints, and data collection plans. Oversee the conduct of clinical trials at study sites, ensuring adherence to protocols and Good Clinical Practice (GCP) standards. Review and interpret trial data to evaluate the safety and efficacy of investigational products.

Join Our Mission:Oruka Therapeutics (Nasdaq: ORKA) is at the forefront of developing cutting-edge biologics aimed at revolutionizing the treatment of chronic skin diseases. Our commitment is to provide patients afflicted by conditions such as plaque psoriasis with unprecedented freedom by achieving significant disease clearance with infrequent dosing—sometimes as little as once or twice a year. We are advancing a proprietary pipeline of potentially best-in-class antibodies that target the fundamental mechanisms of plaque psoriasis and other dermatological and inflammatory ailments. Discover more about us at www.orukatx.com.As we expand our core team, we are looking for exceptional individuals who are not just seeking employment but are passionate about contributing to a broader cause. We value candidates who are eager to foster an inclusive and dynamic company culture.Position Overview:We are in search of a seasoned and motivated leader in regulatory CMC to shape our strategy and execution across various stages of biologics programs. In this role, you will be responsible for the development of high-quality regulatory CMC submissions and will provide guidance to cross-functional teams on global regulatory expectations appropriate for different phases. Ideal candidates will bring extensive expertise in biologics development and manufacturing, particularly in drug substance and product CMC submissions. You will play a crucial role in influencing program strategies, facilitating collaboration across CMC, QA, RA, Supply Chain, and external partners, and driving pivotal decisions that support our expanding biologics pipeline. This highly visible role involves ensuring compliance with FDA, EMA, ICH, and WHO guidelines while meeting corporate and program-level objectives.

Join Xometry (NASDAQ: XMTR), a pioneering digital marketplace that bridges innovative thinkers with manufacturers, enabling the industrial growth of today and tomorrow. Our platform empowers manufacturers with essential resources to expand their businesses while facilitating access to global manufacturing capabilities for buyers from Fortune 1000 companies.We are in search of a Content Marketing & Strategy Manager to spearhead a team of content strategists and act as a key editorial authority for mission-critical accounts. This role will involve shaping the future of marketing through the application of AI and the development of scalable content products and processes within our marketing division.This position is perfect for a leader who thrives on building high-performing teams while being actively involved in execution. You should be passionate about enhancing craft and exploring the potential of AI-driven strategies.Key Responsibilities:Leadership & Team DevelopmentYour primary objective: Build and empower a dynamic content team while providing senior-level oversight for high-stakes situations.Lead, mentor, and nurture a diverse team of content strategists and editors across various manufacturing and industrial sectors.Establish clear standards for content excellence, strategic insights, and client relationships.Act as the senior point of contact for content-related issues, addressing delivery challenges and risks.