Principal Healthcare AI Developer

The Data Platforms Health team at InterSystems is dedicated to creating innovative, healthcare-centric solutions that harness the power of artificial intelligence. As a Principal Healthcare AI Developer within our Database Platforms department, you will play a key role in enhancing AI-driven features and workflows across our flagship products, including Inte…

About SimpliSafeSimpliSafe is a pioneering leader in home security, dedicated to ensuring that every home is a safe haven. We design and develop user-focused hardware, software, and services that safeguard what matters most. Our workplace embraces a hybrid model, fostering a highly collaborative and low-ego culture.Our hybrid work strategy allows teams to alternate between office and home environments. We encourage our teams to gather at our state-of-the-art office at least two core days a week—typically Tuesday, Wednesday, or Thursday—while enjoying the flexibility to choose their work location for the remaining days. This approach enables us to leverage the best aspects of both remote and in-office work.

Acadian Asset Management is a pioneering global systematic investment manager, leading the way in data-driven investing since 1986. Our headquarters in Boston is complemented by offices in Singapore, London, and Sydney, where we manage over $170 billion for esteemed institutions worldwide, including pension funds, endowments, foundations, and sovereign wealth funds. Our mission is to leverage cutting-edge technology, extensive datasets, and multidisciplinary expertise to empower clients in navigating complex markets and uncovering insights often overlooked by traditional methods.What truly distinguishes Acadian is our people. We cultivate a collaborative and intellectually stimulating environment that encourages the testing of ideas, welcomes diverse viewpoints, and fosters innovation. Together, we share a commitment to achieving optimal client outcomes and providing support to one another in our challenging yet rewarding work. Our flexible hybrid work model, comprehensive benefits, and a relaxed yet focused office culture are all designed to support the meaningful and collaborative work that defines Acadian. Position Overview:The Principal AI Engineer serves as a senior technical leader, tasked with defining, designing, and delivering enterprise-level AI platforms and solutions throughout the organization. This role encompasses full ownership of the firm’s AI architecture, covering agentic systems, retrieval-augmented generation (RAG), model integration, evaluation, security, and operationalization. In this hands-on architectural role, the Principal AI Engineer collaborates closely with investment teams and leaders across engineering, data, security, risk, and the broader organization. This position aligns diverse requirements and perspectives into effective solutions that drive innovation and success.

The Principal Applications Developer serves as a senior technical leader, charged with the innovative design, effective delivery, and ongoing evolution of subsystem capabilities or cross-team initiatives. This pivotal role demands the ability to make informed technical decisions that integrate diverse perspectives while guiding teams toward robust, standards-compliant solutions. A strong focus is placed on maintaining architectural integrity, shaping technical strategies, and managing risks across multiple teams and functional areas.Key ResponsibilitiesSteer the end-to-end design and implementation of sophisticated subsystems or solution capabilities.Convert high-level objectives into actionable technical strategies that align with solution direction and business goals.Assess, select, and recommend appropriate technologies, tools, and frameworks, facilitating their integration.Analyze solution methodologies by weighing effort, risk, quality, operability, and sustainability.Independently or collaboratively deliver software projects of substantial scope and complexity.Proactively identify and manage cross-system dependencies and architectural risks.Provide expert technical leadership throughout planning, execution, and resolution of critical challenges.Mentor developers throughout the software delivery lifecycle, guiding thoughtful technical decisions.Articulate technical perspectives in discussions with senior stakeholders, both internal and external.Contribute independently to engagement with customers and industry-related initiatives.

DeepHealth is hiring a Principal Product Manager for the Operations Suite in Boston, Massachusetts. This role shapes the commercialization strategy for a portfolio that includes the Radiology Information System (RIS), Patient Engagement, and Referral Management. The position also leads AI productization efforts, emphasizing workflow automation and analytics across the platform. Key Responsibilities Develop and execute the Operations Suite portfolio strategy, covering RIS, Patient Engagement, Referral Management, and AI-driven solutions. Guide roadmap priorities, ensuring platform architecture matches business goals and market positioning. Formulate pricing and packaging strategies to support market adoption and revenue growth. Establish go-to-market frameworks and build strategic partnerships. Oversee the AI portfolio within the Operations Suite, including developing AI-native applications integrated into RIS workflows. Advance productization of intelligent automation and operational insights throughout the suite. Support innovation and portfolio expansion by driving cross-enterprise integrations and collaborating with industry partners such as RadNet to validate and scale solutions. Primary Duties Lead the multi-year strategy for the RIS and DeepHealth Operations Suite™, focusing on expanding market reach and driving growth in enterprise imaging operations. Align portfolio strategy with DeepHealth’s modernization and AI initiatives. Engage with strategic customers and industry stakeholders to validate product direction and identify emerging market needs. Drive innovation by advancing modular platform capabilities.

Role overview Aidence seeks a Principal Product Manager based in Boston, Massachusetts to lead its Operations Suite portfolio. The position focuses on shaping the commercialization strategy for products such as the Radiology Information System (RIS), Patient Engagement, and Referral Management. This role also guides AI initiatives within the suite. What you will do Develop and implement strategies for the Operations Suite, with attention to automation, analytics, and AI-driven features across RIS, Patient Engagement, and Referral Management. Refine commercialization plans, including pricing models and product packaging, to drive market adoption and form strategic partnerships. Oversee the AI portfolio by leading the development of AI-powered applications and integrating intelligent automation into operational workflows. Work closely with partners to support business growth and evaluate new market opportunities. Impact This leadership role plays a key part in positioning Aidence as a recognized provider in enterprise imaging operations across target markets.

Join our dynamic team as a Principal Software Engineer specializing in Program Analysis for AI! We are on the lookout for a highly skilled software engineer to spearhead the development of next-generation transpilation tools that leverage AI and advanced verification techniques. Your work will play a crucial role in bridging the gap between algorithm development and the deployment of these algorithms in embedded systems.In this pivotal position, you will lead the design and implementation of innovative code generation pipelines that integrate Generative AI, Static Analysis, and Formal Verification methods to facilitate the translation of code from one programming language to another.

Asimov builds tools for designing living systems, combining mammalian synthetic biology with software to support next-generation therapeutics. The Biologics Cell Line Development team in Boston, MA, is growing, and we're seeking a Principal Scientist to help lead our efforts in CHO-based cell line development for biologic therapeutics moving into clinical trials. Role Overview This Principal Scientist position calls for a scientific leader ready to manage a team and drive innovation in cell line development. The role involves designing and executing complex experiments, improving expression systems, and collaborating closely with teams across synthetic biology, modeling, process development, and analytics. The work directly supports Asimov’s mission to advance biological engineering in a startup environment. What You Will Do Oversee CHO cell line development, including transfection, cloning, characterization, and cell banking using advanced technologies. Develop new genetic components, engineer host cell lines, and refine development processes to improve biologics production. Stay current with emerging practices in biologics cell line development and manufacturing, applying new strategies to ongoing projects. Represent the cell line development group on cross-functional projects, making key decisions and communicating progress and plans. Contribute to the scientific community by presenting at conferences, filing patents, and publishing peer-reviewed research. Lead and mentor a team of at least three scientists, providing technical guidance and supporting their career growth. Qualifications At least 8 years of experience in CHO-based cell line development, with a focus on IgG and bispecific expression in an industrial setting. Demonstrated success in creating innovative solutions and experimental approaches in cell line development. Experience managing and developing scientific teams. Strong communication skills for effective work across multidisciplinary groups.

Asimov is seeking a highly skilled and experienced Senior Scientist/Principal Scientist in Biologics Cell Line Development to join our innovative team in Boston, MA. In this pivotal role, you will lead the development of high-yield mammalian cell lines for the production of biologics. You will collaborate closely with cross-functional teams to optimize production processes and ensure the successful translation of cell line development from research to clinical applications.

Join us in transforming how the Department of Defense (DoD) approaches multi-billion-dollar force design decisions. As a Senior Principal Software Engineer, you will integrate physics-based simulations, dynamic computing, and validated AI code generation to develop state-of-the-art wargaming platforms. We are looking for a proactive leader who can architect and develop a scalable, cloud-distributed simulation environment while motivating a small, dedicated team through hands-on leadership.Your ResponsibilitiesDesign & Implement: Create a robust, interactive physics simulation that operates efficiently across cloud and on-premises clusters.Own the Core Codebase: Manage the modern C++ codebase, focusing on multi-threaded performance optimization and continuous integration practices.Collaborate: Work closely with product and AI teams to incorporate verified, AI-generated algorithms directly into a developer SDK for platform enhancement.Prototype & Iterate: Deliver functional capabilities to government end-users in weeks, not months, through rapid prototyping.Set Engineering Standards: Uphold high coding standards, document processes thoroughly, and mentor team members through code reviews and pair programming.

At InterSystems, we're at the forefront of transforming healthcare operations through our innovative cloud-based technology solutions. Our Cloud Development team specializes in integrating state-of-the-art InterSystems technologies with leading public cloud services to tackle complex, high-stakes challenges faced by healthcare organizations.In a fast-paced atmosphere that champions continuous innovation, we excel through creative problem-solving, collaboration, and a steadfast commitment to excellence. Every member of our team is vital to our customers’ success, fostering an environment of mutual trust and accountability. We view change and challenges as opportunities for growth.As a Principal Healthcare Cloud Engineer, you will merge in-depth technical skills with strategic vision and leadership. You will take charge of the architecture, automation, and operational excellence of large-scale, mission-critical healthcare workloads—leading cross-functional teams and mentoring engineers while working closely with product, security, and executive stakeholders.

Rebuild Manufacturing is building an AI-powered platform to improve hardware product development. The platform connects with tools that hardware teams already use, helping them track change requests and share important context. By coordinating across different disciplines, it keeps projects moving smoothly as requirements shift. Supported by a parent company with deep roots in engineering and manufacturing, the team is focused on closing communication gaps in hardware development. The goal: make sure every update and decision reaches the right people at the right time. Role overview The Senior AI Engineer will design and build the core AI agents that drive the platform. This work involves developing systems that can spot potential issues in hardware workflows, offer timely assistance, and help teams stay aligned as projects evolve. What you will do Create AI systems that integrate with existing engineering tools Develop features to coordinate change requests and share critical information Build solutions that help engineering teams anticipate and resolve workflow challenges Locations Greater Boston, MA Los Angeles, CA United States (other locations considered)

Sales Development RepresentativeLocation: Boston, MAHybrid (2 days in-office per week)About ClaspClasp is an innovative, venture-backed startup dedicated to redefining access to education and career opportunities. We are committed to transforming the way employers attract and retain essential talent while addressing the pressing issue of student debt. Our cutting-edge platform effectively links employers, educational institutions, and diverse talent, fostering a mutually beneficial ecosystem through accessible education financing. More than just a fintech, we are a transformative force for economic mobility.Recognized as a Forbes Fintech 50 company and a portfolio entity of the Society of Human Resource Management (SHRM), Clasp has garnered accolades such as “43 Start Ups to Bet Your Career On in 2025” from Business Insider. We are driven by a passion for social impact and innovation, striving to reshape the workforce of tomorrow, one opportunity at a time. Join us in empowering learners and unlocking fulfilling careers that catalyze positive change in their communities and beyond.What We NeedWe are seeking a motivated, creative, and skilled Sales Development Representative (SDR) to join our Clasp Talent Sales Team. This role is pivotal in generating a robust sales pipeline by identifying and engaging with key decision-makers in the healthcare sector who could benefit from Clasp Talent’s innovative offerings.As an SDR, you will be at the forefront of our market strategy, sparking interest, initiating conversations, and qualifying leads for our employer-facing sales team. You will utilize various outreach methods (including email, phone, LinkedIn, and other innovative channels), participate in industry events and conferences, and collaborate closely with our sales team to cultivate high-quality opportunities.This position is ideal for individuals who thrive in dynamic, mission-driven environments, have a strong desire to learn, enjoy building connections, and are not deterred by cold outreach.Key ResponsibilitiesIdentify and engage decision-makers at hospital systems and healthcare employers to generate qualified leads.Conduct high-volume outreach through various communication channels to create interest in our services.Collaborate with the sales team to ensure smooth transition of leads and optimize sales strategies.Attend and represent Clasp at industry conferences and networking events.Continuously learn and adapt to the evolving landscape of healthcare and education financing.

At Hi Marley, we believe that insurance plays a crucial role in people's lives during their most challenging moments. Our mission is to revolutionize communication in the property and casualty (P&C) industry, ensuring that these critical interactions are faster, simpler, and more empathetic for both carriers and their clients. We develop AI-driven software that keeps the claims conversation seamless and connected. If you are passionate about blending operational excellence and automation with a personal touch, we’d love to hear from you.As we continue to grow our enterprise presence, we are in search of a Principal Solutions Consultant to collaborate on our most strategic and intricate opportunities. In this highly autonomous and revenue-critical position, you will partner with Sales leadership to define solution strategies for leading P&C insurers, conducting discovery sessions, translating business challenges into compelling solution narratives, and helping executives envision what’s achievable.This role is ideal for a proactive individual who enjoys solving complex problems and influencing high-stakes agreements. You will be deeply involved in enterprise opportunities, engaging with senior stakeholders, guiding solution strategies, and ensuring alignment between technology, business value, and customer outcomes.

Motional is on the lookout for a highly skilled Principal Engineer to join our Planning team. In this pivotal role, you will be responsible for designing innovative motion planning and control systems that ensure the safe, efficient, and comfortable operation of our autonomous fleet in intricate environments. We seek an individual with a strong background in advanced algorithm development and robust software engineering, committed to shaping production-ready autonomous vehicles. If you are passionate about autonomous driving and enjoy tackling real-world challenges in a dynamic field, we welcome your application.Key Responsibilities:Lead the research and development of groundbreaking algorithms and subsystems for motion planning within autonomous driving, enhancing the Operational Design Domain. This encompasses advanced search-based and geometry-driven methods, alongside decision-making under uncertainty, with a focus on probabilistic techniques.Oversee cross-functional initiatives to create or enhance interfaces aimed at solving complex problems.Continuously monitor system performance to pinpoint areas for enhancement and formulate technical strategies to address shortcomings.Guide cross-functional project teams to deliver comprehensive solutions, showcasing the ability to think beyond the planning system's limitations.Architect and integrate sophisticated motion planning and prediction algorithms, leading their assessment and optimization for real-world applications.Design and develop a resilient, scalable, and high-performance codebase that enables rapid exploration, prototyping, and thorough evaluation of new motion planning methodologies and algorithms.Facilitate technical collaboration and ensure seamless integration with upstream perception and prediction components, as well as downstream trajectory optimization, tracking, and control systems, guaranteeing optimal end-to-end system performance.Utilize your extensive software development and research expertise to mentor others in best software practices, fostering a culture of technical excellence.Mentor junior and senior team members, promoting a culture of product-focused engineering, rigorous research, and advanced development.

Join a dynamic team at Recorded Future, the world's leading and largest intelligence company, with over 1,000 intelligence professionals serving more than 1,900 clients globally!We are on the lookout for a Principal Software Engineer who will be instrumental in enhancing our Engineering team. You will be responsible for designing and scaling the data pipelines that fuel our Security Intelligence Graph. As a Principal Software Engineer, your role will involve working on both application code and infrastructure to efficiently collect, transform, and deliver structured threat data, which includes tracking malware infrastructure, phishing campaigns, spam networks, command-and-control systems, and more. You will be a key contributor in driving architectural improvements and ensuring our platform's scalability as it evolves.

At Klaviyo, we embrace the diverse experiences and perspectives that each Klaviyo (our affectionate term for team members) brings to our dynamic workplace. We believe that everyone deserves a chance to succeed and appreciate unique backgrounds beyond traditional qualifications. If you feel you align closely with this role, we encourage you to apply. To explore more about life at Klaviyo and how we empower creators to take charge of their destinies, please visit our careers page. As a hands-on Principal Engineer specializing in compute, networking, storage, runtimes (e.g., Kubernetes), CI/CD, and observability, you will be instrumental in architecting a robust service platform that facilitates rapid and secure deployments. This is an individual contributor role without direct reports; you will lead through exemplary design, coding practices, and incident management, establishing technical standards and service level objectives (SLOs) for our platform services.

About the RoleJoin Parallel Fluidics as we innovate the infrastructure powering the future of life science tools. As the Principal Mechanical Engineer, you will spearhead our most vital engineering initiatives, establish benchmarks for technical excellence, and influence the processes that guide our product development and manufacturing. We seek an experienced engineering leader with extensive knowledge in electromechanical system design, design for manufacturing, and automation. If you are passionate about making a significant impact by transforming groundbreaking products from concept to production in a fast-paced startup environment, we encourage you to apply.Key ResponsibilitiesEngineering LeadershipAct as the principal architect of the engineering processes at Parallel Fluidics.Lead critical engineering projects that align with our mission.Serve as a technical expert for various internal projects.Identify and implement improvements to our engineering systems and tools.Mentor junior and senior engineers across various disciplines.Provide progress reports and insights to company leadership.Product DevelopmentOversee the transition of Parallel’s next-generation hardware products from concept to scalable production.Identify and evaluate potential high-volume manufacturing partners.Facilitate the transfer of high-volume products from in-house production to third-party manufacturers.Manufacturing SystemsIdentify opportunities to enhance our in-house designed manufacturing equipment.Design experiments and testing methods to optimize manufacturing processes.Collaborate with the manufacturing team to pinpoint gaps and explore improvement opportunities.

Join Mendix, a Leader in Low-Code Application Development:Low-code is revolutionizing software development with its visual approach, allowing the automation of every step in the application lifecycle. Gartner forecasts that by 2024, low-code will account for over 65% of application development activities. As the global leader in enterprise low-code, Mendix is transforming how applications are created. Our platform fosters collaboration between Business and IT teams, empowering organizations to engage in the application development process. Many industry pioneers, including Ford, Zurich Insurance, Freshfields, and Red Bull, utilize Mendix to rapidly realize their innovative ideas. Mendix has consistently been recognized as a Leader in reports from Gartner and Forrester, securing the top position in the 2021 Gartner® Magic Quadrant for Multiexperience Development Platforms. About Mendix, A Siemens Business: Siemens is among the Top 10 Global Software Companies and recognized by Fast Company as one of the Most Innovative Companies in the World! Since Siemens acquired Mendix in 2018, Siemens Digital Industries Software has been at the forefront of digital transformation, enhancing the digital enterprise where engineering, manufacturing, and electronics converge to shape the future of innovation. Mendix employees thrive in a fast-paced environment backed by Siemens’ extensive resources and legacy. Position Overview: Principal Presales Consultant – Digital, Data, Analytics & AI Siemens is reshaping how businesses leverage data for actionable insights. By integrating Mendix low-code applications with advanced data, analytics, and AI platforms, we empower organizations to transition from insights to AI-driven operational impact on a large scale.With the recent acquisition of Altair Graph Studio, Siemens now provides a Knowledge Graph platform that models and interprets intricate data, facilitating the development of Generative AI, Agentic AI, and autonomous systems.We are looking for a dynamic Principal Presales Consultant to guide clients through their enterprise AI transformation journeys, aligning business challenges with Siemens’ comprehensive digital, data, and AI solutions.

Ellevation Education is expanding its Product Design team to drive a pivotal transformation from a series of isolated solutions to a cohesive English Language Development (ELD) platform. Central to this transformation is the design process. As we integrate compliance, instruction, and assessment into streamlined workflows, we are in search of adept designers capable of not just envisioning the user experience but also crafting solutions that present a unified system rather than disparate tools. We are seeking a highly skilled Principal Product Designer to spearhead our UX strategy and advance our design systems. This role requires a blend of systems thinking, leadership in cross-research and development (R&D) design, and the establishment of benchmarks for AI-enhanced design workflows within the team. As a hands-on contributor, you will collaborate with senior Product and Engineering colleagues to shape the strategy and enhance our design system, known as Backpack. Our Product Culture Our organization is structured into small, resilient product teams that create specialized solutions. These teams operate cross-functionally, enabling product, design, and engineering to work in tandem—what we refer to as DevPro—minimizing functional silos. We emphasize outcomes over output, prioritizing early user engagement, validating hypotheses through research and prototyping, and rapidly iterating towards solutions that inspire high confidence. While we operate within distinct teams, we maintain a strong focus on the integration and consistency of our solutions. Consistency is a fundamental aspect of our overarching goals, rather than a mere preference. Designers are expected to leverage AI tools as on-demand collaborators to explore concepts swiftly—whether generating variations, stress-testing ideas, or accelerating the transition from problem identification to prototyping. This approach is not intended to replace craftsmanship but to enhance what can be achieved within time constraints. Your performance will be assessed based on your output using these tools, rather than solely on manual efforts. We value Product Designers who possess strategic thinking capabilities and can approach challenges from various perspectives, balance trade-offs, and express how solutions fulfill both user and business needs. We celebrate accountability for results: conducting experiments, adjusting strategies based on insights, and delivering products that drive meaningful change. This is a hybrid role based out of our headquarters in Boston, MA.