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Experience Level
Senior Level Manager
About the job
The Engine supports Tough Tech entrepreneurs who are developing solutions for major global challenges. As a nonprofit, the organization connects founders with infrastructure, funding, and operational support to help turn breakthrough science and technology into real-world impact.
Role overview
The Chief Growth Officer (CGO) will lead The Engine through its next phase of growth. This executive shapes partnership strategies, drives revenue initiatives, and works to strengthen the organization’s market position. The CGO also serves as a strategic advisor to the CEO and leadership team, providing input on key organizational decisions.
Who should apply
Experienced leaders with a background in Tough Tech, either as entrepreneurs or commercial executives
Individuals with a track record of scaling organizations and launching first-of-a-kind (FOAK) projects
Candidates who have advocated for Tough Tech founders and engaged with the broader ecosystem
The Engine supports Tough Tech entrepreneurs who are developing solutions for major global challenges. As a nonprofit, the organization connects founders with infrastructure, funding, and operational support to help turn breakthrough science and technology into real-world impact. Role overview The Chief Growth Officer (CGO) will lead The Engine through its n…
Are you passionate about leveraging bioinformatics to drive innovation in genomics? Join us as a Bioinformatics Engineer at Genomics England. In this role, you will work at the forefront of genomic medicine, utilizing your skills in computational biology to analyze vast datasets and support the development of groundbreaking healthcare solutions.
Full-time|$120K/yr - $170K/yr|On-site|Cambridge, MA
Charles River Analytics, a proud member of the GRVTY family, is dedicated to developing innovative solutions and cutting-edge technology to address some of the world’s most pressing challenges. Our dynamic team of tech entrepreneurs collaborates to lead advancements in artificial intelligence, robotics, smart sensing, and human-centered computing. Our research and development initiatives not only enhance government programs but also unlock new opportunities within the commercial sector. As part of GRVTY, we are excited to expand our capabilities while maintaining our commitment to excellence in national security domains. Are you ready to join us in accelerating our mission-driven innovations? We would love to hear from you! We are currently seeking a motivated and experienced senior researcher who specializes in Human-Systems Integration, Human Factors, or Human-Computer Interaction. In this role, you will create groundbreaking tools and interfaces that enable users to effectively collaborate with technology in demanding work environments. As a leader, you will guide and expand teams of researchers, designers, and engineers to analyze work contexts and user requirements, develop innovative human-AI interaction concepts, and demonstrate and evaluate interactive prototypes. Your role will involve defining and directing technical projects, fostering strong partnerships with customers, sponsors, and collaborators. Additionally, you will share your expertise in Human Systems, working alongside cross-disciplinary teams to explore new research opportunities in exciting technical fields.
Location: Cambridge, UK | Employment Type: Full-time | Contract Type: Permanent | Work Arrangement: HybridSalary Range: £90,000 to £115,000 depending on experience + Bonus + BenefitsWe are open to considering part-time applications for this role. Please specify your preferred working hours in your cover letter.About UsAt Riverlane, we are on a mission to master quantum error correction (QEC), paving the way for breakthroughs in material science, climate science, and drug design. Quantum computers are set to tackle some of humanity's most pressing challenges, and we are proud to lead the industry in QEC technology. Our team thrives on a blend of expertise, innovation, and passion, which are essential to overcoming this complex problem. With over $125M in funding, we collaborate with top global quantum hardware providers and government agencies to make fault-tolerant quantum computing a reality.
Join Riverlane as a Senior Verification Engineer in our Cambridge office. This full-time, permanent position offers a hybrid work environment.Salary: £60,000 to £88,000 (depending on experience) + Bonus + BenefitsThe salary range for this role accommodates various levels of experience. Offers will reflect your expertise, including relevant industry experience, transferable skills, and notable achievements.We also welcome part-time applications. Please indicate your preferred working schedule in your cover letter.
Full-time|$170K/yr - $191K/yr|On-site|Cambridge, MA
Amylyx Pharmaceuticals is dedicated to revolutionizing the treatment of diseases with significant unmet needs. We embrace challenges as opportunities, driven by a sense of urgency, rigorous scientific methodology, and a steadfast commitment to the communities we serve. Our focus is on clinical-stage development for conditions such as post-bariatric hypoglycemia (PBH), Wolfram syndrome, and amyotrophic lateral sclerosis (ALS).Our mission thrives on our talented team, which embodies core values of audacity, curiosity, authenticity, engagement, and accountability — all of which foster a culture of care. Amylyx has curated a skilled workforce ready to act swiftly because the communities we support cannot afford to wait. If you are passionate about addressing some of the most challenging issues in medicine, we invite you to explore the opportunity below and apply.The OpportunityThe Associate Director of Computer System Validation (CSV) & Quality Compliance will provide enterprise-level leadership, strategic direction, and governance for the validation, lifecycle management, and continuous compliance of GxP-relevant computerized systems, particularly focusing on the Veeva Quality Suite. This position is pivotal in ensuring that our digital quality solutions and supporting systems comply with global regulatory standards (FDA, EMA, ICH, GAMP 5), safeguard data integrity, and maintain a sustainable, inspection-ready status across the organization.This role entails close collaboration with Quality, IT, Regulatory, Clinical, and business process owners to define system requirements, oversee new system implementations and significant enhancements, and promote harmonized, risk-based validation practices. Additionally, this position supervises quality compliance processes such as Change Control, Deviations, CAPA, and continuous improvement, ensuring timely resolutions, trend analysis, and effective governance through leadership of key forums, including Quality Management Review and cross-functional compliance meetings.
Full-time|On-site|Cambridge, England, United Kingdom
Contract type: Full-time, permanent Location: Cambridge, UK Visa sponsorship available Application deadline: Wednesday 20 May 2026, 5pm (UK time) Nu Quantum draws on over ten years of research from the Cavendish Laboratory, focusing on quantum information systems. The team works where quantum computing meets advanced photonic technology, aiming to accelerate the deployment and capabilities of quantum systems. Partnerships with industry leaders and academic collaborators support the development of scalable quantum networking frameworks. Role overview This Optics Engineer role centers on designing, developing, optimizing, and automating advanced optical systems for Nu Quantum’s qubit-photon interface (QPI). The position combines hands-on work with optical setups, microcavity assembly, and system automation. Collaboration is key, with frequent interaction alongside experts in nanofabrication, electronics, mechanical engineering, and software development. Main responsibilities Design and automate optical setups for assembling and characterizing microcavities. Engineer advanced laser and imaging systems; provide optical design and support for AMO experiments. Lead the design and execution of advanced optical experiments and system builds. Develop and implement automation to improve efficiency and control in optical experiments. Align and optimize free-space and fiber-based optical setups to meet strict performance targets. Collect experimental data, analyze results, and draw practical conclusions. Document methodologies, outcomes, and insights to support reproducibility. Communicate complex technical ideas clearly in reports and presentations for both technical and non-technical audiences. Work closely with nanofabrication, electronics, mechanical, and software teams to develop and carry out integrated testing and development plans. Requirements Essential qualifications MSc or PhD in Physics, Optical Engineering, or a related field, or equivalent practical experience. Proven experience designing and implementing optical systems.
Full-time|On-site|Cambridge, England, United Kingdom
Contract Type: Full-time, PermanentLocation: Cambridge, UKClosing date for applications: Wednesday 20th May 2026 at 5pm (UK time)Join Nu Quantum - Pioneering the Future of Quantum TechnologyAt Nu Quantum, we are at the cutting edge of quantum computing and advanced technologies, fueled by innovation and a commitment to diversity and excellence. Our environment fosters collaboration among bright minds from various backgrounds to redefine the limits of technology.Founded to commercialize research developed over the last decade at the prestigious Cavendish Laboratory, Nu Quantum is dedicated to revolutionizing quantum information systems.We are engaged in groundbreaking technology that enhances the utility and expedites the availability of quantum computing systems. By integrating advanced quantum photonic technology, we are establishing a robust and scalable quantum networking infrastructure in collaboration with leading companies and academic institutions.About the RoleWe are seeking a talented Associate Mechanical Engineer or Mid-level Mechanical Engineer (based on experience) to become part of our collaborative team that is dedicated to advancing our innovative quantum networking hardware. The chosen candidate will work closely with multidisciplinary teams encompassing mechanical, electronic, optical, nanofabrication, software, and physics disciplines.ResponsibilitiesAssist in the manufacturing, inspection, and testing of prototypes.Design assembly, testing, and alignment fixtures incorporating electronic, optical, and mechanical elements.Integrate optical devices into opto-mechanical assemblies.Create precision components with tolerances in the micrometer range.Develop user-friendly designs and interfaces for team collaboration.Design systems suitable for ultra-high vacuum (UHV) and cryogenic environments.Provide technical solutions and expertise to support other teams within the company.
This Integration Software Engineer position is based in Cambridge, UK and offers a hybrid working arrangement. The role is full-time and permanent. Salary: £65,000 - £80,000, depending on experience. The final offer will reflect relevant experience, transferable skills, and previous achievements. Applicants are encouraged to mention their preferred working schedule in the cover letter. Role overview This role focuses on integrating software solutions that support the advancement of quantum error correction (QEC) technology. Riverlane works at the intersection of quantum computing and fields such as material science, climate research, and drug design. Integration Software Engineers play a key part in developing and connecting systems that help address the technical challenges of QEC. About Riverlane Riverlane is committed to developing quantum error correction technology, aiming to unlock the full potential of quantum computers. The company partners with quantum hardware providers and government agencies to drive progress toward fault-tolerant quantum computing. With over $125 million raised, Riverlane continues to expand its research and development efforts in this area.
Full-time|$170K/yr - $225K/yr|On-site|Cambridge, MA
Charles River Analytics, a proud member of the GRVTY family, is at the forefront of developing innovative solutions and advanced technologies designed to address some of the most challenging issues faced globally. Our dynamic team of tech entrepreneurs collaborates to enhance AI, robotics, intelligent sensing, and human-centered computing. The research and technology we develop not only propel government initiatives but also unveil new opportunities in the commercial sector. At Charles River, we take immense pride in cultivating a workplace that attracts and retains top-tier talent and creative problem-solvers in the industry. Join us as we strive to accelerate our mission-driven innovations!We are currently seeking a dedicated Senior/Principal Scientist with expertise in Human-Systems Integration, Human Factors, or Human-Computer Interaction. In this role, you will spearhead the development of cutting-edge tools and interfaces that empower users to effectively collaborate with technology in demanding environments.Your responsibilities will include leading and expanding teams of researchers, designers, and engineers to assess work domains and user needs, create novel human-AI interaction concepts, and evaluate interactive prototypes. You will also be responsible for defining and directing technical projects, while fostering robust relationships with clients, sponsors, and collaborators. As a subject matter expert in Human Systems, you will work alongside multidisciplinary teams to explore and pursue research opportunities across various technical domains.
About Graphcore At Graphcore, we are pioneering the next generation of AI computing technology. Our team comprises industry-leading experts in semiconductors, software, and artificial intelligence, dedicated to developing a comprehensive AI compute stack that spans from silicon innovations to extensive data center infrastructure. As a proud member of the SoftBank Group, we are supported by substantial long-term investments, enabling us to advance critical technologies within the rapidly evolving SoftBank AI ecosystem. To capitalize on the immense opportunities in AI, Graphcore is expanding its global workforce. We are uniting the brightest minds to tackle the most challenging problems in an environment where every individual can significantly influence the organization, our products, and the future of artificial intelligence.
Location: Cambridge, MA (Eastern Time / UTC -4) Relocation package available or Remote option for Out-Of-State applicantsStart date: ASAPLanguages: English (required)About the RoleJoin Pragmatike, a dynamic AI startup recognized as a Top 10 GenAI company by GTM Capital, founded by esteemed MIT CSAIL researchers. We are currently seeking a Senior Multicloud Engineer who possesses extensive, hands-on experience in architecting, deploying, and managing production infrastructure across AWS, GCP, and Azure. This pivotal role involves working directly on cloud and platform layers to support large-scale, distributed AI systems for Fortune 500 clients.What You'll DoDesign, deploy, and maintain production infrastructure across AWS, GCP, and Azure.Ensure consistent environments through Infrastructure as Code (Terraform preferred).Manage and operate Kubernetes clusters and containerized applications across multiple cloud environments.Architect and oversee cloud networking solutions (VPC/VNet design, peering, load balancing, and private connectivity).Implement robust monitoring, logging, alerting, and incident response protocols for multicloud systems.Enhance performance, reliability, and cost-efficiency across providers using autoscaling and capacity planning strategies.Support AI training and inference workloads in multicloud settings.Diagnose and resolve complex production issues across compute, networking, storage, and Kubernetes layers.Collaborate with AI, backend, and platform teams to ensure seamless integration with production systems.What We're Looking For5+ years of experience as a Cloud/Platform/Infrastructure Engineer.Proven production experience with AWS, GCP, and Azure (strong expertise in at least one).
Full-time|On-site|Cambridge, England, United Kingdom
Nu Quantum is hiring a Nanofabrication Engineer to join its team in Cambridge, UK. This is a full-time, permanent role with visa sponsorship available. Applications close on Wednesday 27th May 2026 at 5pm (UK time). Nu Quantum commercializes over ten years of research from the Cavendish Laboratory, focusing on quantum computing and advanced quantum photonic technology. The company partners with leading businesses and academic groups to build scalable quantum networking solutions, aiming to accelerate the development and adoption of quantum computing systems. Role overview This position will suit either a Nanofabrication Engineer or Senior Nanofabrication Engineer, depending on experience. The role sits within the hardware R&D group and centers on advancing quantum networking technology. Success in this work depends on achieving high levels of precision and fidelity, supporting multi-core quantum computing. The engineer will work closely with the Photonics Systems team, which brings together expertise in engineering design, optics, integrated photonics, and nanofabrication. The initial project will focus on developing and testing a custom MEMS actuator for Nu Quantum’s next-generation Qubit Photon Interface (QPI) device. What you will do Design, test, and optimize custom MEMS actuators and miniaturized optical cavity module devices for the upcoming Qubit Photon Interface. Develop and refine high-precision assembly processes for aligning and assembling miniaturized optical components. Work with external foundry suppliers and internal process engineers to define and improve microfabrication workflows. Manage design-test-build cycles, including parts inventory, test planning, database management, and technical reporting to ensure timelines and quality standards are met.
Full-time|$192K/yr - $272K/yr|On-site|Cambridge, MA USA
LILA Sciences is seeking a Staff DevOps Engineer to lead the design, deployment, and ongoing improvement of infrastructure and delivery systems. This role blends platform engineering, site reliability, and DevOps practices to build scalable, automated systems that support reliable software delivery in cloud and Kubernetes environments. Collaboration is central: work closely with software developers, laboratory scientists, and machine learning engineers to create the backbone for automated scientific analysis and experiment orchestration. Key Responsibilities Design and implement Kubernetes-based infrastructure to support scientific services, machine learning pipelines, and platform workloads. Ensure production hardening, RBAC, network policies, and compliance with Pod Security Standards. Set up and maintain CI/CD pipelines using GitHub Actions or GitLab CI. Apply best practices including build attestations, SBOM generation, dependency scanning, and container image hardening. Apply Infrastructure-as-Code principles with Terraform and Helm. Implement policy-as-code guardrails (using OPA, Kyverno, or Checkov) and enable drift detection. Manage AWS cloud infrastructure, including EKS clusters, IAM with least privilege, VPC/PrivateLink networking, KMS/Secrets Manager, ECR, S3, and centralized logging and monitoring systems. Develop platform tools to improve deployment, observability, and developer workflows, supporting self-service with secure defaults. Drive reliability engineering practices, focusing on SLOs/SLIs, incident response, capacity planning, and performance optimization across the technology stack. Implement software supply chain security, including artifact signing, registry governance, and vulnerability management. Build and maintain QA and testing infrastructure: static analysis, code quality gates in CI pipelines, automated end-to-end and browser-based regression testing, ephemeral environments for pull request validation, and pre-merge quality checks. Automate operational processes and develop tooling in Python or Go to streamline infrastructure operations and integrate telemetry with observability platforms. Requirements Significant experience in DevOps, Site Reliability Engineering, or Platform Engineering within large-scale cloud environments. Proficiency with cloud deployments (AWS, GCP, etc.) using Infrastructure-as-Code tools such as Terraform and Helm, and expertise in containerization. Strong background in CI/CD systems (GitHub Actions, GitLab CI, or Jenkins) and familiarity with GitOps workflows. Advanced scripting skills in Python or similar languages for automation and tool creation. Comprehensive understanding of Kubernetes operations, including deployments, networking, storage, observability, and troubleshooting. This position is based in Cambridge, MA, USA.
Senior Embedded Software Engineer (Firmware)Location: Cambridge, UK | Employment Type: Full-time | Job Type: Permanent | Work Arrangement: HybridSalary: £70,000 to £90,000 based on experience.The salary range is flexible, as we welcome candidates with varying levels of experience. Offers will be tailored to reflect individual experience, industry background, transferable skills, and notable achievements.Candidates are encouraged to specify their preferred working schedule in their cover letter.
Join the Future of AI at GraphcoreAt Graphcore, we are pioneering the next generation of AI computing technology.Our team comprises seasoned professionals from semiconductor, software, and AI sectors, with extensive expertise in developing a comprehensive AI compute infrastructure—from silicon and software to large-scale data center solutions.As a proud member of the SoftBank Group, we benefit from substantial long-term investment, enabling us to contribute pivotal technology to the rapidly evolving SoftBank AI ecosystem.In response to the immense opportunities within the AI landscape, Graphcore is expanding its global teams, uniting brilliant minds to tackle the most challenging problems in an environment where each member can significantly influence our company, products, and the future of artificial intelligence.
Location: Cambridge, UK (hybrid work arrangement) Type: Full-time, permanent. Part-time applications are also welcome. Please mention your preferred schedule in your cover letter. Salary: £65,000 to £90,000, depending on experience. This range covers a variety of experience levels. Riverlane considers industry background, transferable skills, and notable achievements when making offers. Company mission Riverlane is dedicated to mastering quantum error correction (QEC) to help unlock new possibilities in science and technology. The team works to overcome the technical hurdles that stand between today’s quantum computers and their potential to solve complex problems in material science, climate research, and drug discovery. What sets Riverlane apart With more than $125 million raised, Riverlane is pushing forward in quantum error correction research and development. The company partners with leading quantum hardware firms and government organizations to make fault-tolerant quantum computing a reality. The team brings together a wide range of skills and backgrounds to meet this ambitious goal.
Full-time|$125K/yr - $185K/yr|On-site|Cambridge, Massachusetts, United States
HyperLight, located in Cambridge, Massachusetts, develops thin-film lithium niobate (TFLN) integrated photonics for scalable optical components. Since 2018, the company has supported sectors such as AI and datacom infrastructure, hyperscale computing, quantum computing, and sensing. HyperLight’s TFLN Chiplet™ platform enables modular, integrated system design and supports manufacturability for complex applications. Role overview The Senior Photonics Process Development Engineer leads efforts to develop, refine, and scale fabrication processes for the TFLN platform. This position involves working directly with customers, especially in quantum computing and other emerging areas, to turn technical requirements into robust, scalable manufacturing processes. The role also manages advanced process node development and coordinates process variations to improve device performance. What you will do Define and optimize next-generation and custom fabrication processes for high-performance TFLN photonic integrated circuits (PICs). Collaborate with customers and suppliers to develop processes that meet immediate and future performance needs. Coordinate with internal teams in design, testing, and production to manage development tapeouts, oversee production, and support wafer-level testing. Collaboration and impact This role involves cross-functional work within HyperLight, including direct interaction with customers and suppliers. The Senior Photonics Process Development Engineer helps shape fabrication strategies for new applications and ensures timely delivery of solutions.
Join Riverlane as a Senior Digital Design Engineer in Cambridge, UK. This full-time, permanent position offers a hybrid working model.Salary Range: £70,000 to £90,000 DOE + Bonus + BenefitsWe are flexible and will consider part-time applications. Please specify your preferred working hours in your cover letter.
Location: Cambridge, MA (Eastern Time / UTC -4) Relocation package available or Remote option for Out-Of-State applicantsStart date: ASAPLanguages: English (required)About the RoleJoin Pragmatike, a rapidly expanding AI startup recognized among the Top 10 GenAI companies by GTM Capital and founded by MIT CSAIL researchers.We are on the lookout for a Senior Cloud Engineer (Multicloud) who possesses extensive hands-on expertise in constructing, managing, and scaling production infrastructures across AWS, GCP, and Azure. Your contributions will directly support large-scale, distributed AI systems utilized by Fortune 500 clients.Ideal candidates will have experience in operating genuine multicloud environments, not just limited to a single provider. You will play a pivotal role in creating reliable, scalable systems while effectively managing the complexities of various cloud architectures, networking models, and operational trade-offs.What You'll DoBuild, deploy, and manage production infrastructures across AWS, GCP, and Azure.Ensure consistency across environments using Infrastructure as Code (preferably Terraform).Deploy and manage Kubernetes clusters and containerized applications across multiple cloud platforms.Design and oversee cloud networking (VPC/VNet architecture, peering, load balancing, private connectivity).Implement comprehensive monitoring, logging, alerting, and incident response strategies for multicloud environments.Enhance performance, reliability, and cost-effectiveness across providers through autoscaling and capacity planning.Support AI training and inference workloads in multicloud settings.Troubleshoot intricate production challenges across compute, networking, storage, and Kubernetes layers.Work collaboratively with AI, backend, and platform teams to optimize production systems.What We're Looking For5+ years of experience as a Cloud / Platform / Infrastructure Engineer.Proven production experience with AWS, GCP, and Azure (deep knowledge in at least one).
The Engine supports Tough Tech entrepreneurs who are developing solutions for major global challenges. As a nonprofit, the organization connects founders with infrastructure, funding, and operational support to help turn breakthrough science and technology into real-world impact. Role overview The Chief Growth Officer (CGO) will lead The Engine through its n…
Are you passionate about leveraging bioinformatics to drive innovation in genomics? Join us as a Bioinformatics Engineer at Genomics England. In this role, you will work at the forefront of genomic medicine, utilizing your skills in computational biology to analyze vast datasets and support the development of groundbreaking healthcare solutions.
Full-time|$120K/yr - $170K/yr|On-site|Cambridge, MA
Charles River Analytics, a proud member of the GRVTY family, is dedicated to developing innovative solutions and cutting-edge technology to address some of the world’s most pressing challenges. Our dynamic team of tech entrepreneurs collaborates to lead advancements in artificial intelligence, robotics, smart sensing, and human-centered computing. Our research and development initiatives not only enhance government programs but also unlock new opportunities within the commercial sector. As part of GRVTY, we are excited to expand our capabilities while maintaining our commitment to excellence in national security domains. Are you ready to join us in accelerating our mission-driven innovations? We would love to hear from you! We are currently seeking a motivated and experienced senior researcher who specializes in Human-Systems Integration, Human Factors, or Human-Computer Interaction. In this role, you will create groundbreaking tools and interfaces that enable users to effectively collaborate with technology in demanding work environments. As a leader, you will guide and expand teams of researchers, designers, and engineers to analyze work contexts and user requirements, develop innovative human-AI interaction concepts, and demonstrate and evaluate interactive prototypes. Your role will involve defining and directing technical projects, fostering strong partnerships with customers, sponsors, and collaborators. Additionally, you will share your expertise in Human Systems, working alongside cross-disciplinary teams to explore new research opportunities in exciting technical fields.
Location: Cambridge, UK | Employment Type: Full-time | Contract Type: Permanent | Work Arrangement: HybridSalary Range: £90,000 to £115,000 depending on experience + Bonus + BenefitsWe are open to considering part-time applications for this role. Please specify your preferred working hours in your cover letter.About UsAt Riverlane, we are on a mission to master quantum error correction (QEC), paving the way for breakthroughs in material science, climate science, and drug design. Quantum computers are set to tackle some of humanity's most pressing challenges, and we are proud to lead the industry in QEC technology. Our team thrives on a blend of expertise, innovation, and passion, which are essential to overcoming this complex problem. With over $125M in funding, we collaborate with top global quantum hardware providers and government agencies to make fault-tolerant quantum computing a reality.
Join Riverlane as a Senior Verification Engineer in our Cambridge office. This full-time, permanent position offers a hybrid work environment.Salary: £60,000 to £88,000 (depending on experience) + Bonus + BenefitsThe salary range for this role accommodates various levels of experience. Offers will reflect your expertise, including relevant industry experience, transferable skills, and notable achievements.We also welcome part-time applications. Please indicate your preferred working schedule in your cover letter.
Full-time|$170K/yr - $191K/yr|On-site|Cambridge, MA
Amylyx Pharmaceuticals is dedicated to revolutionizing the treatment of diseases with significant unmet needs. We embrace challenges as opportunities, driven by a sense of urgency, rigorous scientific methodology, and a steadfast commitment to the communities we serve. Our focus is on clinical-stage development for conditions such as post-bariatric hypoglycemia (PBH), Wolfram syndrome, and amyotrophic lateral sclerosis (ALS).Our mission thrives on our talented team, which embodies core values of audacity, curiosity, authenticity, engagement, and accountability — all of which foster a culture of care. Amylyx has curated a skilled workforce ready to act swiftly because the communities we support cannot afford to wait. If you are passionate about addressing some of the most challenging issues in medicine, we invite you to explore the opportunity below and apply.The OpportunityThe Associate Director of Computer System Validation (CSV) & Quality Compliance will provide enterprise-level leadership, strategic direction, and governance for the validation, lifecycle management, and continuous compliance of GxP-relevant computerized systems, particularly focusing on the Veeva Quality Suite. This position is pivotal in ensuring that our digital quality solutions and supporting systems comply with global regulatory standards (FDA, EMA, ICH, GAMP 5), safeguard data integrity, and maintain a sustainable, inspection-ready status across the organization.This role entails close collaboration with Quality, IT, Regulatory, Clinical, and business process owners to define system requirements, oversee new system implementations and significant enhancements, and promote harmonized, risk-based validation practices. Additionally, this position supervises quality compliance processes such as Change Control, Deviations, CAPA, and continuous improvement, ensuring timely resolutions, trend analysis, and effective governance through leadership of key forums, including Quality Management Review and cross-functional compliance meetings.
Full-time|On-site|Cambridge, England, United Kingdom
Contract type: Full-time, permanent Location: Cambridge, UK Visa sponsorship available Application deadline: Wednesday 20 May 2026, 5pm (UK time) Nu Quantum draws on over ten years of research from the Cavendish Laboratory, focusing on quantum information systems. The team works where quantum computing meets advanced photonic technology, aiming to accelerate the deployment and capabilities of quantum systems. Partnerships with industry leaders and academic collaborators support the development of scalable quantum networking frameworks. Role overview This Optics Engineer role centers on designing, developing, optimizing, and automating advanced optical systems for Nu Quantum’s qubit-photon interface (QPI). The position combines hands-on work with optical setups, microcavity assembly, and system automation. Collaboration is key, with frequent interaction alongside experts in nanofabrication, electronics, mechanical engineering, and software development. Main responsibilities Design and automate optical setups for assembling and characterizing microcavities. Engineer advanced laser and imaging systems; provide optical design and support for AMO experiments. Lead the design and execution of advanced optical experiments and system builds. Develop and implement automation to improve efficiency and control in optical experiments. Align and optimize free-space and fiber-based optical setups to meet strict performance targets. Collect experimental data, analyze results, and draw practical conclusions. Document methodologies, outcomes, and insights to support reproducibility. Communicate complex technical ideas clearly in reports and presentations for both technical and non-technical audiences. Work closely with nanofabrication, electronics, mechanical, and software teams to develop and carry out integrated testing and development plans. Requirements Essential qualifications MSc or PhD in Physics, Optical Engineering, or a related field, or equivalent practical experience. Proven experience designing and implementing optical systems.
Full-time|On-site|Cambridge, England, United Kingdom
Contract Type: Full-time, PermanentLocation: Cambridge, UKClosing date for applications: Wednesday 20th May 2026 at 5pm (UK time)Join Nu Quantum - Pioneering the Future of Quantum TechnologyAt Nu Quantum, we are at the cutting edge of quantum computing and advanced technologies, fueled by innovation and a commitment to diversity and excellence. Our environment fosters collaboration among bright minds from various backgrounds to redefine the limits of technology.Founded to commercialize research developed over the last decade at the prestigious Cavendish Laboratory, Nu Quantum is dedicated to revolutionizing quantum information systems.We are engaged in groundbreaking technology that enhances the utility and expedites the availability of quantum computing systems. By integrating advanced quantum photonic technology, we are establishing a robust and scalable quantum networking infrastructure in collaboration with leading companies and academic institutions.About the RoleWe are seeking a talented Associate Mechanical Engineer or Mid-level Mechanical Engineer (based on experience) to become part of our collaborative team that is dedicated to advancing our innovative quantum networking hardware. The chosen candidate will work closely with multidisciplinary teams encompassing mechanical, electronic, optical, nanofabrication, software, and physics disciplines.ResponsibilitiesAssist in the manufacturing, inspection, and testing of prototypes.Design assembly, testing, and alignment fixtures incorporating electronic, optical, and mechanical elements.Integrate optical devices into opto-mechanical assemblies.Create precision components with tolerances in the micrometer range.Develop user-friendly designs and interfaces for team collaboration.Design systems suitable for ultra-high vacuum (UHV) and cryogenic environments.Provide technical solutions and expertise to support other teams within the company.
This Integration Software Engineer position is based in Cambridge, UK and offers a hybrid working arrangement. The role is full-time and permanent. Salary: £65,000 - £80,000, depending on experience. The final offer will reflect relevant experience, transferable skills, and previous achievements. Applicants are encouraged to mention their preferred working schedule in the cover letter. Role overview This role focuses on integrating software solutions that support the advancement of quantum error correction (QEC) technology. Riverlane works at the intersection of quantum computing and fields such as material science, climate research, and drug design. Integration Software Engineers play a key part in developing and connecting systems that help address the technical challenges of QEC. About Riverlane Riverlane is committed to developing quantum error correction technology, aiming to unlock the full potential of quantum computers. The company partners with quantum hardware providers and government agencies to drive progress toward fault-tolerant quantum computing. With over $125 million raised, Riverlane continues to expand its research and development efforts in this area.
Full-time|$170K/yr - $225K/yr|On-site|Cambridge, MA
Charles River Analytics, a proud member of the GRVTY family, is at the forefront of developing innovative solutions and advanced technologies designed to address some of the most challenging issues faced globally. Our dynamic team of tech entrepreneurs collaborates to enhance AI, robotics, intelligent sensing, and human-centered computing. The research and technology we develop not only propel government initiatives but also unveil new opportunities in the commercial sector. At Charles River, we take immense pride in cultivating a workplace that attracts and retains top-tier talent and creative problem-solvers in the industry. Join us as we strive to accelerate our mission-driven innovations!We are currently seeking a dedicated Senior/Principal Scientist with expertise in Human-Systems Integration, Human Factors, or Human-Computer Interaction. In this role, you will spearhead the development of cutting-edge tools and interfaces that empower users to effectively collaborate with technology in demanding environments.Your responsibilities will include leading and expanding teams of researchers, designers, and engineers to assess work domains and user needs, create novel human-AI interaction concepts, and evaluate interactive prototypes. You will also be responsible for defining and directing technical projects, while fostering robust relationships with clients, sponsors, and collaborators. As a subject matter expert in Human Systems, you will work alongside multidisciplinary teams to explore and pursue research opportunities across various technical domains.
About Graphcore At Graphcore, we are pioneering the next generation of AI computing technology. Our team comprises industry-leading experts in semiconductors, software, and artificial intelligence, dedicated to developing a comprehensive AI compute stack that spans from silicon innovations to extensive data center infrastructure. As a proud member of the SoftBank Group, we are supported by substantial long-term investments, enabling us to advance critical technologies within the rapidly evolving SoftBank AI ecosystem. To capitalize on the immense opportunities in AI, Graphcore is expanding its global workforce. We are uniting the brightest minds to tackle the most challenging problems in an environment where every individual can significantly influence the organization, our products, and the future of artificial intelligence.
Location: Cambridge, MA (Eastern Time / UTC -4) Relocation package available or Remote option for Out-Of-State applicantsStart date: ASAPLanguages: English (required)About the RoleJoin Pragmatike, a dynamic AI startup recognized as a Top 10 GenAI company by GTM Capital, founded by esteemed MIT CSAIL researchers. We are currently seeking a Senior Multicloud Engineer who possesses extensive, hands-on experience in architecting, deploying, and managing production infrastructure across AWS, GCP, and Azure. This pivotal role involves working directly on cloud and platform layers to support large-scale, distributed AI systems for Fortune 500 clients.What You'll DoDesign, deploy, and maintain production infrastructure across AWS, GCP, and Azure.Ensure consistent environments through Infrastructure as Code (Terraform preferred).Manage and operate Kubernetes clusters and containerized applications across multiple cloud environments.Architect and oversee cloud networking solutions (VPC/VNet design, peering, load balancing, and private connectivity).Implement robust monitoring, logging, alerting, and incident response protocols for multicloud systems.Enhance performance, reliability, and cost-efficiency across providers using autoscaling and capacity planning strategies.Support AI training and inference workloads in multicloud settings.Diagnose and resolve complex production issues across compute, networking, storage, and Kubernetes layers.Collaborate with AI, backend, and platform teams to ensure seamless integration with production systems.What We're Looking For5+ years of experience as a Cloud/Platform/Infrastructure Engineer.Proven production experience with AWS, GCP, and Azure (strong expertise in at least one).
Full-time|On-site|Cambridge, England, United Kingdom
Nu Quantum is hiring a Nanofabrication Engineer to join its team in Cambridge, UK. This is a full-time, permanent role with visa sponsorship available. Applications close on Wednesday 27th May 2026 at 5pm (UK time). Nu Quantum commercializes over ten years of research from the Cavendish Laboratory, focusing on quantum computing and advanced quantum photonic technology. The company partners with leading businesses and academic groups to build scalable quantum networking solutions, aiming to accelerate the development and adoption of quantum computing systems. Role overview This position will suit either a Nanofabrication Engineer or Senior Nanofabrication Engineer, depending on experience. The role sits within the hardware R&D group and centers on advancing quantum networking technology. Success in this work depends on achieving high levels of precision and fidelity, supporting multi-core quantum computing. The engineer will work closely with the Photonics Systems team, which brings together expertise in engineering design, optics, integrated photonics, and nanofabrication. The initial project will focus on developing and testing a custom MEMS actuator for Nu Quantum’s next-generation Qubit Photon Interface (QPI) device. What you will do Design, test, and optimize custom MEMS actuators and miniaturized optical cavity module devices for the upcoming Qubit Photon Interface. Develop and refine high-precision assembly processes for aligning and assembling miniaturized optical components. Work with external foundry suppliers and internal process engineers to define and improve microfabrication workflows. Manage design-test-build cycles, including parts inventory, test planning, database management, and technical reporting to ensure timelines and quality standards are met.
Full-time|$192K/yr - $272K/yr|On-site|Cambridge, MA USA
LILA Sciences is seeking a Staff DevOps Engineer to lead the design, deployment, and ongoing improvement of infrastructure and delivery systems. This role blends platform engineering, site reliability, and DevOps practices to build scalable, automated systems that support reliable software delivery in cloud and Kubernetes environments. Collaboration is central: work closely with software developers, laboratory scientists, and machine learning engineers to create the backbone for automated scientific analysis and experiment orchestration. Key Responsibilities Design and implement Kubernetes-based infrastructure to support scientific services, machine learning pipelines, and platform workloads. Ensure production hardening, RBAC, network policies, and compliance with Pod Security Standards. Set up and maintain CI/CD pipelines using GitHub Actions or GitLab CI. Apply best practices including build attestations, SBOM generation, dependency scanning, and container image hardening. Apply Infrastructure-as-Code principles with Terraform and Helm. Implement policy-as-code guardrails (using OPA, Kyverno, or Checkov) and enable drift detection. Manage AWS cloud infrastructure, including EKS clusters, IAM with least privilege, VPC/PrivateLink networking, KMS/Secrets Manager, ECR, S3, and centralized logging and monitoring systems. Develop platform tools to improve deployment, observability, and developer workflows, supporting self-service with secure defaults. Drive reliability engineering practices, focusing on SLOs/SLIs, incident response, capacity planning, and performance optimization across the technology stack. Implement software supply chain security, including artifact signing, registry governance, and vulnerability management. Build and maintain QA and testing infrastructure: static analysis, code quality gates in CI pipelines, automated end-to-end and browser-based regression testing, ephemeral environments for pull request validation, and pre-merge quality checks. Automate operational processes and develop tooling in Python or Go to streamline infrastructure operations and integrate telemetry with observability platforms. Requirements Significant experience in DevOps, Site Reliability Engineering, or Platform Engineering within large-scale cloud environments. Proficiency with cloud deployments (AWS, GCP, etc.) using Infrastructure-as-Code tools such as Terraform and Helm, and expertise in containerization. Strong background in CI/CD systems (GitHub Actions, GitLab CI, or Jenkins) and familiarity with GitOps workflows. Advanced scripting skills in Python or similar languages for automation and tool creation. Comprehensive understanding of Kubernetes operations, including deployments, networking, storage, observability, and troubleshooting. This position is based in Cambridge, MA, USA.
Senior Embedded Software Engineer (Firmware)Location: Cambridge, UK | Employment Type: Full-time | Job Type: Permanent | Work Arrangement: HybridSalary: £70,000 to £90,000 based on experience.The salary range is flexible, as we welcome candidates with varying levels of experience. Offers will be tailored to reflect individual experience, industry background, transferable skills, and notable achievements.Candidates are encouraged to specify their preferred working schedule in their cover letter.
Join the Future of AI at GraphcoreAt Graphcore, we are pioneering the next generation of AI computing technology.Our team comprises seasoned professionals from semiconductor, software, and AI sectors, with extensive expertise in developing a comprehensive AI compute infrastructure—from silicon and software to large-scale data center solutions.As a proud member of the SoftBank Group, we benefit from substantial long-term investment, enabling us to contribute pivotal technology to the rapidly evolving SoftBank AI ecosystem.In response to the immense opportunities within the AI landscape, Graphcore is expanding its global teams, uniting brilliant minds to tackle the most challenging problems in an environment where each member can significantly influence our company, products, and the future of artificial intelligence.
Location: Cambridge, UK (hybrid work arrangement) Type: Full-time, permanent. Part-time applications are also welcome. Please mention your preferred schedule in your cover letter. Salary: £65,000 to £90,000, depending on experience. This range covers a variety of experience levels. Riverlane considers industry background, transferable skills, and notable achievements when making offers. Company mission Riverlane is dedicated to mastering quantum error correction (QEC) to help unlock new possibilities in science and technology. The team works to overcome the technical hurdles that stand between today’s quantum computers and their potential to solve complex problems in material science, climate research, and drug discovery. What sets Riverlane apart With more than $125 million raised, Riverlane is pushing forward in quantum error correction research and development. The company partners with leading quantum hardware firms and government organizations to make fault-tolerant quantum computing a reality. The team brings together a wide range of skills and backgrounds to meet this ambitious goal.
Full-time|$125K/yr - $185K/yr|On-site|Cambridge, Massachusetts, United States
HyperLight, located in Cambridge, Massachusetts, develops thin-film lithium niobate (TFLN) integrated photonics for scalable optical components. Since 2018, the company has supported sectors such as AI and datacom infrastructure, hyperscale computing, quantum computing, and sensing. HyperLight’s TFLN Chiplet™ platform enables modular, integrated system design and supports manufacturability for complex applications. Role overview The Senior Photonics Process Development Engineer leads efforts to develop, refine, and scale fabrication processes for the TFLN platform. This position involves working directly with customers, especially in quantum computing and other emerging areas, to turn technical requirements into robust, scalable manufacturing processes. The role also manages advanced process node development and coordinates process variations to improve device performance. What you will do Define and optimize next-generation and custom fabrication processes for high-performance TFLN photonic integrated circuits (PICs). Collaborate with customers and suppliers to develop processes that meet immediate and future performance needs. Coordinate with internal teams in design, testing, and production to manage development tapeouts, oversee production, and support wafer-level testing. Collaboration and impact This role involves cross-functional work within HyperLight, including direct interaction with customers and suppliers. The Senior Photonics Process Development Engineer helps shape fabrication strategies for new applications and ensures timely delivery of solutions.
Join Riverlane as a Senior Digital Design Engineer in Cambridge, UK. This full-time, permanent position offers a hybrid working model.Salary Range: £70,000 to £90,000 DOE + Bonus + BenefitsWe are flexible and will consider part-time applications. Please specify your preferred working hours in your cover letter.
Location: Cambridge, MA (Eastern Time / UTC -4) Relocation package available or Remote option for Out-Of-State applicantsStart date: ASAPLanguages: English (required)About the RoleJoin Pragmatike, a rapidly expanding AI startup recognized among the Top 10 GenAI companies by GTM Capital and founded by MIT CSAIL researchers.We are on the lookout for a Senior Cloud Engineer (Multicloud) who possesses extensive hands-on expertise in constructing, managing, and scaling production infrastructures across AWS, GCP, and Azure. Your contributions will directly support large-scale, distributed AI systems utilized by Fortune 500 clients.Ideal candidates will have experience in operating genuine multicloud environments, not just limited to a single provider. You will play a pivotal role in creating reliable, scalable systems while effectively managing the complexities of various cloud architectures, networking models, and operational trade-offs.What You'll DoBuild, deploy, and manage production infrastructures across AWS, GCP, and Azure.Ensure consistency across environments using Infrastructure as Code (preferably Terraform).Deploy and manage Kubernetes clusters and containerized applications across multiple cloud platforms.Design and oversee cloud networking (VPC/VNet architecture, peering, load balancing, private connectivity).Implement comprehensive monitoring, logging, alerting, and incident response strategies for multicloud environments.Enhance performance, reliability, and cost-effectiveness across providers through autoscaling and capacity planning.Support AI training and inference workloads in multicloud settings.Troubleshoot intricate production challenges across compute, networking, storage, and Kubernetes layers.Work collaboratively with AI, backend, and platform teams to optimize production systems.What We're Looking For5+ years of experience as a Cloud / Platform / Infrastructure Engineer.Proven production experience with AWS, GCP, and Azure (deep knowledge in at least one).