Senior / Staff Software Engineer - Computational Chemistry & Molecular Dynamics

At Genesis Molecular AI, we are assembling an elite software engineering team dedicated to revolutionizing drug discovery using cutting-edge machine learning, biophysical simulations, and advanced computational chemistry. We seek passionate engineers eager to contribute to the development of innovative medicines while playing a pivotal role in enhancing our …

At Roblox, we empower millions of users to explore, create, play, and connect through immersive 3D digital experiences, all crafted by our vibrant community of developers and creators.Our mission is to redefine how people come together from any corner of the globe and on any device. We are committed to fostering a community that connects a billion people with optimism and civility, and we are on the lookout for exceptional talent to join us in this endeavor.A career at Roblox means you will be at the forefront of shaping human interaction, tackling unique technical challenges at scale, and contributing to the creation of safe, civil shared experiences for all.As a Senior Software Engineer on our Systems team, your contributions will directly impact the foundational elements of Roblox. You will develop robust software that supports our extensive community of over 2 million developers, enabling them to push the boundaries of interactive gaming. Your work will encompass various aspects of the engine, including threading, memory management, physics, and scripting. If you possess a passion for C++ and thrive in high-performance, real-time applications, you will find a welcoming environment within our Game Engine team.Your responsibilities will include:Crafting engine code in C++ for critical sub-systems within the Roblox game engine.Developing systems for data synchronization between server and client, implementing game-aware data streaming, and optimizing resource usage to ensure seamless gameplay across diverse devices.Contributing to every application developed by Roblox, from mobile clients to cloud-based servers.Your qualifications include:A minimum of 4 years of experience working on intricate challenges in extensive C++ codebases.Proficiency with system-level pointers, templates, and raw memory blocks.A strong understanding of game engine architecture or a desire to learn.Experience in building reliable, functioning systems.A curiosity and commitment to staying updated with technological advancements.

Join IXL Learning, a leader in personalized education technology serving millions worldwide, as a Front-End Software Engineer. In this role, you will be pivotal in shaping the user interface of our innovative IXL product.As a member of our Product Engineering team, you will develop user-centric features for our website and integrate back-end services that enhance our educational offerings. Your work will include maintaining our practice engine, crafting analytics tools for teachers, and creating personalized recommendations for students.Utilizing advanced technologies such as React, you will create engaging and dynamic components that resonate with users. We take pride in developing products that make a difference in education, and we are excited to welcome a passionate engineer to our team. At IXL, we value creativity and user experience as essential components of our mission to transform education through technology.

About the TeamBecome a part of a groundbreaking team at the intersection of artificial intelligence and biochemistry.At Genesis Molecular AI, we have assembled a close-knit team of distinguished deep learning researchers, software engineers, and pioneers in drug discovery. Our ambitious mission is to develop the next generation of AI foundation models that will enable innovative therapies for patients suffering from serious illnesses.We go beyond the application of machine learning in biology; we conduct pioneering research at the confluence of machine learning, physics, and computational chemistry, continuously pushing the limits of each discipline. You will collaborate with top-tier multidisciplinary researchers to design and implement scalable generative foundation models, backed by extensive computational resources and large-scale simulations.About the RoleThis exceptional opportunity is tailored for a scientist passionate about leveraging advanced AI to tackle real-world challenges in drug discovery. You will play a pivotal role in connecting our long-term research initiatives with our active drug discovery programs. Your objective will be to construct, assess, monitor, and refine our cutting-edge models, integrating them directly into ongoing drug programs and leading the efforts in model validation, deployment, and analysis to inform the discovery of new medications.As both a translator and strategist, you will ensure that our research targets the most pressing challenges and that our drug hunters can harness the full capabilities of our leading AI platform. This role necessitates an in-depth understanding of cheminformatics, computational chemistry, and experimental techniques, robust data science skills, and an aptitude for articulating complex concepts to a diverse, multidisciplinary team.Positions are available at multiple seniority levels: Senior, Staff, and Principal.

Join IXL Learning, a leader in personalized education technology, as a Senior Software Engineer. We are dedicated to developing innovative learning solutions that positively influence the lives of millions. If you have a fervor for technology and education, we want you on our team to enhance our award-winning educational products and create new offerings that inspire learners worldwide.This full-time role is based at our San Mateo, CA headquarters. Enjoy a Monday-Friday work schedule with the flexibility to work from home one day a week.

At Genesis Molecular AI, we are assembling a premier software engineering team dedicated to revolutionizing drug discovery through advanced machine learning, biophysical simulations, and computational chemistry. We seek passionate engineers eager to contribute to groundbreaking medicine development and play an integral role in enhancing our software platform.Your ResponsibilitiesDevelop and enhance tools for visualizing molecular structures and proteins, analyzing machine learning models, and managing intricate chemical workflows.Collaborate closely with machine learning engineers and medicinal chemists to innovate and implement new computational methods for predicting molecular properties.Assist in scaling our core infrastructure to efficiently process billions of data points and thousands of concurrent deep learning and molecular dynamics tasks.Your ProfileA proficient software engineer capable of writing high-quality code promptly while adhering to our coding standards.A critical thinker who approaches problems from first principles rather than relying solely on established patterns.Eager to expand knowledge about biochemistry and the drug development lifecycle.What We ProvideAn opportunity to contribute to impactful tools and products that are actively utilized to expedite the discovery of novel medicines.A team of highly skilled professionals in AI, software engineering, and chemistry, characterized by intellectual curiosity and humility. Our team engages in weekly discussions of 1-2 research papers in machine learning or chemistry to stay updated and inspire innovative ideas.Application & Hiring TimelineApplication Deadline: April 24, 2026Resume Review Begins: May 4, 2026Interviews Commence: May 11, 2026About Genesis Molecular AIGenesis Molecular AI is at the forefront of creating foundational models for molecular AI, ushering in a new era in drug design and development. Our innovative generative and predictive AI platform, GEMS (Genesis Exploration of Molecular Space), combines AI with physics to produce and optimize drug development models.

Join Our Innovative TeamAt Genesis Molecular AI, we are a dedicated group of skilled deep learning researchers, software engineers, and pioneers in drug discovery. Our collective mission is to develop pioneering AI foundation models that will enable revolutionary therapies for patients suffering from severe conditions.We don't merely implement machine learning in biology; we engage in groundbreaking research at the convergence of machine learning, physics, and computational chemistry, challenging the limits of each discipline. As part of the Genesis AI team, you will collaborate with top-tier multidisciplinary researchers to design and construct generative and discriminative foundation models from an extensive range of molecular data, utilizing state-of-the-art computing resources and large-scale simulations.Your RoleThis position provides a unique platform for a scientific innovator to contribute to the future of generative AI in drug discovery. As an integral member of the Genesis AI team, you will guide and propel our research initiatives focusing on foundation models. You will spearhead significant research projects in areas such as reinforcement learning, innovative model architectures, and advanced pretraining and post-training techniques. Your primary goal will be to develop groundbreaking models and insights crucial for discovering new medications.This role demands a profound curiosity and a collaborative mindset. You will be an essential team player, working closely with our exceptional engineers and drug discovery specialists to transform complex concepts into reality. Additionally, we encourage you to be an influential voice in the scientific community, and we will actively support your efforts to publish research breakthroughs at premier ML conferences such as NeurIPS, ICML, and ICLR.Positions are available at several levels of seniority: Senior, Staff, and Principal.Key ResponsibilitiesLead transformative research projects from initiation to execution, addressing core challenges in generative modeling for molecular systems.Design and develop innovative models and algorithms, leveraging the latest advancements in diffusion models, flow matching, reinforcement learning, large language models, and other cutting-edge fields.

About the Role Roblox is hiring a Principal Software Engineer focused on Compute Provisioning at our San Mateo, CA office. This role centers on building and improving the systems that power Roblox’s cloud infrastructure. Work closely with engineers and other teams to create and support scalable solutions for compute provisioning across the platform.

Join IXL Learning, a premier innovator in personalized education solutions utilized by millions globally, as a Senior Software Engineer on our Unification Team. This impactful team is dedicated to enhancing technical excellence across IXL and our affiliated brands.In this pivotal role, you will spearhead large-scale, cross-functional engineering projects aimed at unifying our infrastructure, standardizing tools and processes, and developing reusable, scalable, and reliable systems. Your contributions will foster enhanced collaboration, expedite development cycles, and bolster product performance company-wide.We seek engineers who are passionate about tackling intricate technical challenges, excel in collaborative settings, and are driven by the mission to improve systems that empower millions of learners.

About the TeamBecome a part of a pioneering team at the intersection of artificial intelligence and biochemistry.At Genesis Molecular AI, we are a dynamic collective of distinguished deep learning researchers, software engineers, and innovators in drug discovery. Our ambitious mission is to develop the next frontier of AI foundation models to unlock revolutionary treatments for patients battling serious diseases.We are not merely applying machine learning to biological problems; we are engaged in groundbreaking research that bridges machine learning, physics, and computational chemistry, challenging the limits of each discipline. The Genesis AI team is constructing the engine for this transformation. You will collaborate closely with leading multidisciplinary researchers to design and implement generative and discriminative foundation models at scale, utilizing extensive computational resources and large-scale simulations.About the RoleThis is a unique opportunity for a scientific innovator to influence the future landscape of generative AI in drug discovery. As a pivotal member of the Genesis AI team, you will direct our research strategy for foundation models. You will spearhead critical research initiatives in areas such as reinforcement learning, innovative model architectures, and advanced pretraining and post-training techniques. Your primary goal will be to develop transformative models and insights that play a crucial role in the discovery of new medications.This position demands a profound curiosity and a commitment to collaboration. You will be an integral team player, partnering closely with our exceptional engineers and drug discovery specialists to realize complex concepts. Additionally, we encourage you to engage with the scientific community, and we will actively support your endeavors to publish significant research findings in prestigious ML conferences such as NeurIPS, ICML, and ICLR.We are hiring for various levels of seniority: Senior, Staff, and Principal.Your ResponsibilitiesLead innovative research projects from inception to execution, addressing fundamental challenges in generative modeling for molecular systems.Design and develop advanced models and algorithms, leveraging the latest advancements in diffusion models, flow matching, reinforcement learning, and large language models.Conduct large-scale experiments utilizing our premier computational resources to validate your research.

Join IXL Learning, a leading developer of personalized educational products impacting millions worldwide. We are on the lookout for passionate Software Engineers who are excited about integrating technology with education. As part of our innovative team, you will contribute to enhancing our existing educational products and creating new ones that positively influence learners' lives.This is a full-time opportunity based in our San Mateo, CA headquarters, with a Monday to Friday in-office schedule, and the flexibility to work from home one day each week.Key ResponsibilitiesCollaborate with a talented team of engineers to initiate fresh projects and enhance our current codebase.Develop back-end architecture, application logic, and user interfaces for educational products.Lead your team through the development cycle, including design, coding, documentation, testing, debugging, and optimization.Provide accurate project estimates, evaluate feasibility, and explore new platforms and technologies for implementation.Engage in clear communication and collaboration across multiple teams to design and launch exceptional products.

Skydio stands at the forefront of the drone industry, pioneering autonomous flight technology that is shaping the future of aerial mobility. Our team excels in the realms of artificial intelligence, cutting-edge hardware and software development, and a relentless focus on customer satisfaction. We aim to broaden the accessibility of drone technology to a diverse range of users, from utility inspectors to first responders and military personnel.Our mission is to harness transformative AI to create unparalleled flying machines for both enterprise and governmental use. Central to our autonomy system is the ability to understand the world through semantic and geometric insights derived from visual data. We are continually pushing the limits of real-time deep learning networks to enhance the capabilities of intelligent mobile robots.About the Role:If you’re passionate about utilizing extensive structured video data to tackle challenges in Computer Vision (CV)—including object detection, tracking, optical flow estimation, and segmentation—we would be thrilled to connect with you.How You’ll Make an Impact:Develop high-performance deep learning inference solutions for CV tasks, ensuring high throughput and minimal latency across various hardware platforms.Profile and analyze CV and Vision Language Models (VLMs) to identify performance bottlenecks, optimization opportunities, and enhance power efficiency in deep learning inference workloads.Design and implement comprehensive MLOps workflows for model deployment, monitoring, and re-training.Apply advanced Machine Learning expertise to leverage training/runtime frameworks or model efficiency tools to elevate system performance.Create innovative approaches to enhance training efficiency.Implement GPU kernels for custom architectures and optimized inference.Design and develop SDKs that empower customers and external developers to create autonomous workflows using machine learning.Leverage your expertise to uphold and enhance Skydio’s engineering standards.

Join IXL Learning, a leader in developing personalized educational products utilized by millions worldwide. We are looking for an experienced Technical Lead to oversee a dynamic team of engineers and deliver both technical and project leadership. This full-time position is based at our headquarters in San Mateo, CA, with the flexibility to work from home one day per week.Key ResponsibilitiesBuild and lead a high-performing engineering team.Mentor engineers and project leads to foster job satisfaction and support their professional growth.Clearly communicate the company's mission, goals, and values to the team.Collaborate with project managers, designers, and QA teams to exceed product usability and quality standards.

Join IXL Learning, a pioneering developer of personalized learning products that enrich the educational experiences of millions worldwide. We are on the lookout for enthusiastic new graduates with a strong passion for technology and education. As a Software Engineer, you will immerse yourself in our codebase and make immediate contributions to our impactful educational products while also innovating new solutions. You will enhance your current skills and acquire new ones, working within diverse teams including our Core Technology group focused on back-end engineering, our front-end engineers utilizing cutting-edge technologies like React, our Mobile team creating iOS and Android applications, or our Full-stack units eager for versatile engineers.We take immense pride in crafting products that transform the lives of learners around the globe, and we are excited to welcome you to our dynamic team.This position is based in our San Mateo, CA headquarters, and we do offer H1B visa sponsorship for qualified candidates.

Join IXL Learning, a leader in personalized educational solutions that enhance the learning experience for millions worldwide. We are on the lookout for a passionate Software Engineering Manager who will guide a talented team of engineers in delivering innovative software solutions. This role involves not only overseeing projects but also diving into the intricacies of software design and engineering. As a mentor, you will play a crucial role in fostering the growth of your team while establishing effective processes that drive productivity and excellence. At IXL, we take pride in our impactful products, and we are excited to welcome you aboard to help shape the future of education.This is a full-time role based in our San Mateo, CA headquarters, with a work schedule from Monday to Friday and the opportunity to work from home one day each week.

About Wisdom AIAt Wisdom AI, we are on a transformative journey to simplify data interactions for businesses. Our mission is to make data insights accessible, enabling swift and informed decision-making. We prioritize simplicity and clarity, guided by core values that shape our culture:Default to Action: We thrive on speed and value progress.Customer-Obsessed: Our goal is to maximize customer value.One Team: We communicate openly and challenge ideas respectfully.Role OverviewWe are seeking a talented Backend/Infrastructure Engineer to join our founding team. You will play a pivotal role in developing machine learning and data pipelines designed for efficiency, security, and scalability. As a Platforms Engineer, you will focus on deployments, observability, and enhancing the production environment to better serve our customers.Key ResponsibilitiesOversee the observability and deployment processes within the Wisdom stack.Collaborate with software and sales engineers to establish effective production change management processes and tools.Utilize modern cloud infrastructure to create cost-effective and scalable systems.Engage with customers and founders to shape the engineering roadmap.Contribute to the development of the engineering culture and technology stack.

About UsAt Dyneti, we are committed to revolutionizing digital payments by ensuring they are both seamless and secure. Our flagship product, DyScan, empowers digital merchants to combat fraud and enhance conversion rates through innovative technology that captures credit card images.Founded by a seasoned fraud prevention expert from Uber, Dyneti has successfully attracted investment from notable backers, including Y Combinator. With hundreds of millions of credit card scans processed globally, our clientele consists of Fortune 100 companies and some of the most promising tech unicorns.Job OverviewWe invite you to join Dyneti as a member of our pioneering engineering team. This role offers you the unique opportunity to collaborate closely with the CEO in developing new features and launching innovative products, particularly in the exciting realm of deep learning.

Skydio stands as the preeminent drone company in the United States and a global leader in autonomous flight technology, which is vital for the future of drones and aerial mobility. Our team is comprised of experts in artificial intelligence, cutting-edge hardware and software development, operational excellence, and a relentless focus on customer satisfaction. We aim to empower a diverse range of drone users, from utility inspectors to first responders and military personnel in various scenarios.About the Role:At the heart of our autonomy system is the ability to learn a semantic and geometric understanding of the world through visual data. We are at the forefront of real-time deep learning networks, striving to enhance intelligent aerial robots capable of navigating unknown environments and delivering substantial operational value. If you are passionate about applying deep learning to real-world challenges in computer vision and autonomy, we encourage you to apply.As a Deep Learning Engineer, your primary responsibility will be to train and deploy optimized models for our products. You will tackle complex challenges including optical flow estimation, stereo depth estimation, object detection, segmentation and tracking, visual place recognition, localization and mapping, few-shot learning, occupancy networks, and automated path planning.Your Impact:Design, implement, and deploy computer vision and multimodal deep learning models for Skydio’s autonomy system.Utilize vast amounts of real-world video and sensor data for data mining, curation, labeling, training, and evaluation.Employ large-scale diverse synthetic data to enhance deep learning algorithms.Utilize state-of-the-art foundation models for knowledge distillation and efficient learning.Refine and optimize models for low-latency performance on embedded hardware.Develop evaluation benchmarks and metrics to assess the performance of autonomous systems.Contribute broadly to various aspects of the software as required.Your Qualifications:A Master’s or Ph.D. in Computer Science, Electrical Engineering, or a related field.Proven hands-on experience in designing, training, and deploying deep learning models.Strong ability to produce high-quality, well-architected code (preferably in Python/PyTorch).

About Us:At Fireworks AI, we are pioneering the future of generative AI infrastructure. Our cutting-edge platform provides unparalleled model quality with the fastest and most scalable inference capabilities in the industry. We have been independently recognized as the leader in LLM inference speed and are at the forefront of innovative projects like our proprietary function calling and multimodal models. As a Series C company valued at $4 billion, we are backed by premier investors including Benchmark, Sequoia, Lightspeed, Index, and Evantic. Our dynamic team of builders includes veterans from Meta PyTorch and Google Vertex AI, and we are driven by ambition and collaboration.The Role: We are seeking a talented Software Engineer specializing in Performance Optimization to enhance the speed and efficiency of our AI infrastructure. This role demands ownership of performance optimization across all system layers, from low-level GPU kernels to large-scale distributed systems. Your primary focus will be on maximizing the efficiency of our most demanding workloads, which encompass large language models (LLMs), vision-language models (VLMs), and next-generation video models.You will collaborate closely with teams in research, infrastructure, and systems to identify performance bottlenecks, implement innovative optimizations, and scale our AI systems to meet the real-world demands of production use cases. Your contributions will significantly influence the speed, scalability, and cost-effectiveness of some of the most advanced generative AI models globally.

Join the innovative team at IXL Learning, the leader in educational technology with a mission to enhance language learning through our renowned Rosetta Stone products. We are on the lookout for Senior Software Engineers who are not just skilled in technology but also passionate about language education. You will play a crucial role in developing and enhancing features for our successful platforms that support immersive learning in 25 languages.This full-time position is based in our San Mateo, CA headquarters, with a Monday to Friday in-office schedule and the flexibility to work from home one day each week.Key ResponsibilitiesCollaborate with a dynamic team of engineers to initiate new projects and improve existing codebases.Design and implement back-end infrastructure, application logic, and user interfaces for our products.Provide accurate project estimates, assess feasibility, and explore new technologies for implementation.Engage in clear communication and collaboration across multiple teams to deliver exceptional products.Mentor fellow engineers and share your expertise and insights.Qualifications6+ years of software engineering experience.Bachelor's degree or higher in Computer Science or a related field.Proficient in programming languages such as Ruby, Go, or Java.Excellent communication, analytical thinking, and problem-solving abilities.Familiarity with modern best practices in JavaScript, HTML, and CSS.Knowledge of AWS, MySQL, MongoDB, GraphQL/Node, and React is advantageous.A strong passion for leveraging technology to enhance language learning.