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Senior/Executive Medical Director, Clinical Development (New Indications)

Alumis Inc.South San Francisco
On-site Full-time $300K/yr - $400K/yr

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Experience Level

Senior Level Manager

Qualifications

Key ResponsibilitiesClinical Development Strategy & LeadershipDirect the design, planning, and execution of Phase 1 and Phase 2 clinical trials for A-005 and additional pipeline candidates in emerging therapeutic areas. Develop and enhance comprehensive clinical development plans, including study synopses, protocols, and integrated strategies for new indications. Provide clinical and scientific oversight to cross-functional study teams, ensuring alignment on objectives, timelines, and deliverables. Collaborate with Translational Medicine and Research teams to assess and prioritize new indication opportunities based on scientific merit, competitive landscape, and unmet medical needs. Study Execution & OversightAct as the Medical Monitor for assigned Phase 1 and 2 studies, guaranteeing patient safety and the scientific integrity of the trials. Oversee the medical components of study conduct, including safety monitoring, protocol amendments, and data analysis. Partner with Clinical Operations, Biostatistics, and Regulatory Affairs to ensure effective study execution and high-quality data outcomes. Lead interactions with Data Safety Monitoring Boards (DSMBs) and provide medical insights for safety evaluations. Regulatory & External EngagementContribute to regulatory submissions and interactions, ensuring alignment with scientific and clinical goals.

About the job

At Alumis Inc., we are dedicated to revolutionizing the treatment of autoimmune diseases through precision medicine. Despite advancements in treatment over the past two decades, many patients with immunologic conditions still experience significant challenges. Our mission is to fundamentally improve outcomes for these patients.

Position Summary

We are actively seeking a highly qualified Senior or Executive Medical Director to spearhead the clinical development strategy for Phase 1 and Phase 2 trials assessing envudeucitinib and A-005, targeting new indications for the expansion of our innovative pipeline. This pivotal role will not only shape our clinical development portfolio from indication selection to proof-of-concept studies but will also establish you as a vital scientific leader collaborating with internal teams, regulatory bodies, and the broader medical community.

About Alumis Inc.

Alumis Inc. is a pioneering precision medicine company committed to altering the landscape of autoimmune disease treatment. By focusing on innovative therapies, we aim to provide hope and improved health outcomes for patients who continue to face challenges despite existing treatment options.

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